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- 耐えられない,がまんできない
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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/03/12 04:38:33」(JST)
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Look up unbearable in Wiktionary, the free dictionary. |
Unbearable may refer to:
- "Unbearable" (CSI), an episode of the American crime drama CSI: Crime Scene Investigation
- Unbearable (book), the fifth in a series of collections of short stories by Australian author Paul Jennings
UpToDate Contents
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English Journal
- Aggression-impulsivity, mental pain, and communication difficulties in medically serious and medically non-serious suicide attempters.
- Gvion Y, Horresh N, Levi-Belz Y, Fischel T, Treves I, Weiser M, David HS, Stein-Reizer O, Apter A.Author information Department of Clinical Psychology, Bar Ilan University, Ramat Gan, Israel; Department of Clinical Psychology, Tel Aviv-Jaffa Academic Center, Tel Aviv, Israel. Electronic address: yari@kadi.co.il.AbstractBACKGROUND: Unbearable mental pain, depression, and hopelessness have been associated with suicidal behavior in general, while difficulties with social communication and loneliness have been associated with highly lethal suicide attempts in particular. The literature also links aggression and impulsivity with suicidal behavior but raises questions about their influence on the lethality and outcome of the suicide attempt.
- Comprehensive psychiatry.Compr Psychiatry.2014 Jan;55(1):40-50. doi: 10.1016/j.comppsych.2013.09.003. Epub 2013 Oct 8.
- BACKGROUND: Unbearable mental pain, depression, and hopelessness have been associated with suicidal behavior in general, while difficulties with social communication and loneliness have been associated with highly lethal suicide attempts in particular. The literature also links aggression and impuls
- PMID 24209607
- Mental Pain, Communication Difficultiesand Medically Serious Suicide Attempts: A Case-Control Study.
- Levi-Belz Y, Gvion Y, Horesh N, Fischel T, Treves I, Or E, Stein-Reisner O, Weiser M, David HS, Apter A.Author information a Department of Behavioral Sciences , Ruppin Academic Center , Emek Hefer , Israel.AbstractBackground Medical severe suicide attempts (MSSA) are epidemiologically very similar to individuals who complete suicide. Thus the investigation of individuals who have made medically serious attempts (MSSA) may aid to our understanding of the risk factors for completed suicide. The aim of this study was to assess the role of mental pain and communicationdifficulties in MSSA. Method 336 subjects were divided into 4 groups: 78 meeting criteria for MSSA compared with116 subjects who made a medically non-serious suicide attempt (MNSSA); 47psychiatric controls with no history of suicidal behavior and 95 healthy controls. Mental pain variants (e.g., hopelessness), facets of communicationdifficulties (e.g., self-disclosure) as well as socio-demographic and clinical characteristics were assessed. Results The MSSA had significantly higher communication difficulties than the other three groups. Moreover, the interaction between mental pain and communication difficulties explained some of the variance in suicide lethality, above and beyond the contribution of each component alone. Conclusions This report underlines the importance of mental pain for suicide attempts in general while difficulties in communicationabilities play a critical role in differentiating MSSA from MNSSA. The co-existence of unbearable mental pain with difficulties in communication significantly enhances the risk for more lethal forms of suicidal behavior.
- Archives of suicide research : official journal of the International Academy for Suicide Research.Arch Suicide Res.2013 Dec 18. [Epub ahead of print]
- Background Medical severe suicide attempts (MSSA) are epidemiologically very similar to individuals who complete suicide. Thus the investigation of individuals who have made medically serious attempts (MSSA) may aid to our understanding of the risk factors for completed suicide. The aim of this stud
- PMID 24350568
- Angiotensin-II induces phosphorylation of ERK1/2 and promotes aortic adventitial fibroblasts differentiating into myofibroblasts during aortic dissection formation.
- Wang Z, Ren Z, Hu Z, Hu X, Zhang H, Wu H, Zhang M.Author information Department of Cardiothoracic Surgery, Renmin Hospital of Wuhan University, #99 Ziyang Road, Wuhan, 430060, Hubei, China, wangzhiwp@gmail.com.AbstractThe development of acute aortic dissection (AD) is attributed to unbearable wall tension superimposed on disordered of cells and extracellular matrix (ECM) in the aortic wall. Adventitial fibroblasts (AFs) phenotypic differentiation response to stress exhibits essential function to regulate the remolding of vascular. Little is known about the AFs phenotypic differentiation and its possible mechanism in patients with AD. In this study, we examined their roles in AD. Surgical specimens of the aorta from AD patients (n = 10) and controls (n = 10) were tested for α-smooth muscle actin (α-SMA), extracellular signal-regulated kinase 1,2 (ERK1/2) and phospho-ERK1/2 expression, respectively by western blot. When compared with controls, protein levels of α-SMA was significantly decreased and levels of phospho-ERK1/2 was increased significantly in the aortic wall from patients with AD. Immunohistochemistry results showed elevated staining of both α-SMA and phospho-ERK1/2 in the adventitia of the aortic wall from patients with AD, on the contrary, staining of α-SMA in the media was decreased compared with controls. In vitro, the Raf/MEK/ERK pathway was involved in Ang-II-induced phenotypic differentiation and matrix metalloproteinase-2 (MMP-2) mRNA expression in AFs. This study provides a new insight into the biological action of AFs and phospho-ERK1/2 promoting phenotypic differentiation and MMP-2 expression, suggesting an important role of AFs in leading to disorder the delicate balance of ECM metabolism in the aortic wall, so that AFs may be an essential participant during AD formation.
- Journal of molecular histology.J Mol Histol.2013 Dec 17. [Epub ahead of print]
- The development of acute aortic dissection (AD) is attributed to unbearable wall tension superimposed on disordered of cells and extracellular matrix (ECM) in the aortic wall. Adventitial fibroblasts (AFs) phenotypic differentiation response to stress exhibits essential function to regulate the remo
- PMID 24343777
Japanese Journal
- ワーズワスの『序曲』における「悲しみ」について : "Waiting for the Horses"エピソードからの考察(中国四国英文学研究)
- 両側腎多発結節状腫瘤と多発脊椎転移病変を認めた前駆B細胞性リンパ芽球性リンパ腫の1例
- タペンタドール誘発性過活動型せん妄にオピオイドスイッチングが有効だった1例
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