tup

　

WordNet

1. in a stupid manner; "he had stupidly bought a one way ticket" (同)doltishly
2. having eight units or components (同)eightfold, eight-fold

PrepTutorEJDIC

1. 雄羊
2. 愚かに[も]
3. 目立ちたがる人,(人の注意を引くために)いたずらをする人
4. (物の)作り,体裁 / 身なり;(特に)いっぷう変わった服装

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/10/30 21:15:42」(JST)

wiki en

[Wiki en表示]

Tup or TUP may refer to:

• Tup, an uncastrated male sheep
• Tupping, copulation in sheep, or the sheep mating season
• Twopence (disambiguation), two pence
• Tupac Shakur (1971–1996), American rapper and actor
• Technological University of the Philippines
• Telephone User Part, a telephone system protocol used in some parts of the world
• The Urantia Papers, a spiritual and philosophical book
• Tupelo Regional Airport, Tupelo, Mississippi, United States

English Journal

• Urinary excretion of porphyrins, porphobilinogen and δ-aminolaevulinic acid following an attack of acute intermittent porphyria.

• Marsden JT1, Rees DC.Author information 1Department of Clinical Biochemistry, King's College Hospital, , London, UK.AbstractBACKGROUND AND OBJECTIVES: The porphyrias are a group of rare, mainly inherited, diseases caused by a deficiency of one of the enzymes of the haem biosynthesis pathway. The biochemical hallmark of an acute attack is an increase in urine porphobilinogen (PBG), together with an increase in urinary excretion of δ-aminolaevulinic acid (ALA) and total urine porphyrins (TUP). In patients with acute intermittent porphyria (AIP) the concentrations of the porphyrin precursors are thought to remain elevated for many years following an acute attack, although this has not been well documented.
• Journal of clinical pathology.J Clin Pathol.2014 Jan;67(1):60-5. doi: 10.1136/jclinpath-2012-201367. Epub 2013 Aug 1.
• BACKGROUND AND OBJECTIVES: The porphyrias are a group of rare, mainly inherited, diseases caused by a deficiency of one of the enzymes of the haem biosynthesis pathway. The biochemical hallmark of an acute attack is an increase in urine porphobilinogen (PBG), together with an increase in urinary exc
• PMID 23908454

• High concentrations of a urinary biomarker of polyphenol intake are associated with decreased mortality in older adults.

• Zamora-Ros R1, Rabassa M, Cherubini A, Urpí-Sardà M, Bandinelli S, Ferrucci L, Andres-Lacueva C.Author information 1Nutrition and Food Science Department, XaRTA INSA, INGENIO-CONSOLIDER Program, Fun-C-food CSD2007-063, Pharmacy School, University of Barcelona, Barcelona, Spain.AbstractPolyphenols might have a role in the prevention of several chronic diseases, but evaluating total dietary polyphenol (TDP) intake from self-reported questionnaires is inaccurate and unreliable. A promising alternative is to use total urinary polyphenol (TUP) concentration as a proxy measure of intake. The current study evaluated the relationship between TUPs and TDPs and all-cause mortality during a 12-y period among older adult participants. The study population included 807 men and women aged 65 y and older from the Invecchiare in Chianti study, a population-based cohort study of older adults living in the Chianti region of Tuscany, Italy. TUP concentrations were measured at enrolment (1998-2000) using the Folin-Ciocalteau assay after a solid-phase extraction. TDPs were also estimated at baseline throughout a validated food frequency questionnaire and using our database based on USDA and Phenol-Explorer databases. We modeled associations using Kaplan-Meier survival and Cox proportional hazards models, with adjustment for potential confounders. During the 12-y follow-up, 274 participants (34%) died. At enrollment, TUP excretion adjusted for age and sex tended to be greater in participants who survived [163 ± 62 mg gallic acid equivalents (GAE)/d)] than in those who died (143 ± 63 mg GAE/d) (P = 0.07). However, no significant differences were observed for TDPs. In the multivariable Cox model, participants in the highest tertile of TUP at enrolment had a lower mortality rate than those in the lowest tertile [HR = 0.70 (95% CI: 0.49-0.99); P-trend = 0.045], whereas no significant associations were found between TDP and overall mortality. TUP is an independent risk factor for mortality among community-dwelling older adults, suggesting that high dietary intake of polyphenols may be associated with longevity.
• The Journal of nutrition.J Nutr.2013 Sep;143(9):1445-50. doi: 10.3945/jn.113.177121. Epub 2013 Jun 26.
• Polyphenols might have a role in the prevention of several chronic diseases, but evaluating total dietary polyphenol (TDP) intake from self-reported questionnaires is inaccurate and unreliable. A promising alternative is to use total urinary polyphenol (TUP) concentration as a proxy measure of intak
• PMID 23803472

• Total synthesis of tubulysin U and its C-4 epimer.

• Yang XD1, Dong CM, Chen J, Ding YH, Liu Q, Ma XY, Zhang Q, Chen Y.Author information 1The State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Nankai University, 300071, Tianjin, PR China.AbstractThe Tup fragments of tubulysins were synthesized with a tandem reaction as the key step, and unexpected diastereoselectivity was observed in the first Grignard addition stage. The coupling of the enolate of a thiazolyl ketone with chiral sulfinimines furnished the backbone of the Tuv fragment with over 100:1 d.r. and high yield. Thus, tubulysin U and C-4 epi-tubulysin U were prepared in a highly selective and efficient manner. The results of the MTT assay furthermore indicated that C-4 epi-tubulysin U maintained significant growth inhibition activities against several cancer cell lines.
• Chemistry, an Asian journal.Chem Asian J.2013 Jun;8(6):1213-22. doi: 10.1002/asia.201300051. Epub 2013 Apr 10.
• The Tup fragments of tubulysins were synthesized with a tandem reaction as the key step, and unexpected diastereoselectivity was observed in the first Grignard addition stage. The coupling of the enolate of a thiazolyl ketone with chiral sulfinimines furnished the backbone of the Tuv fragment with o
• PMID 23576385

Japanese Journal

• GTS1 Induction Causes Derepression of Tup1-Cyc8-Repressing Genes and Chromatin Remodeling through the Interaction of Gts1p with Cyc8p

• SANADA Mitsuaki,KURODA Kouichi,UEDA Mitsuyoshi
• Bioscience, biotechnology, and biochemistry 75(4), 740-747, 2011-04-23
• … A genome-wide transcriptional analysis identified genes upregulated in response to GTS1 induction, most of which were found to be regulated by the Tup1-Cyc8 co-repressor. … These results suggest that inhibition of the Tup1-Cyc8 complex and subsequent SWI/SNF-dependent chromatin remodeling result in Gts1p-mediated gene derepression. …
• NAID 10028271704

• W-03 CST-NU COLLABORATES FOREIGN UNIVERSITIES FOR THE GLOBAL INTEGRATION OF MECHANICAL ENGINEERING EDUCATION(International Session)

• Basario Kristian Gunayan,TAKEI Masahiro
• JSEE annual conference international session proceedings 2010, 24-28, 2010-08-21
• … The international relationship initiated by the College of Science and Technology of Nihon University (CST-NU) between two big Universities from different countries, the Technological University of the Philippines (TUP) and Xi'an University of Technology (XUT) as examples of successfully free trade of learning was historically reviewed in this paper. …
• NAID 110007811816

Related Links

• 車買い取りT-UPはトヨタ以外の車種も買取・査定｜TOYOTAの ...

「車売るならT-UP」でお馴染みのトヨタの車買い取りネットワーク、ティーアップの公式サイト。トヨタ以外のメーカーの自動車も買取・査定いたします。TOYOTAは中古車販売の自社ルートがあるため中古車買取り価格にも自信があります。

• トヨタ T-UP（車買取） | トヨタ自動車WEBサイト

トヨタの買取りネットワークT-UPの紹介ページです。T-UPはトヨタ以外の全メーカー買取り・査定が可能。独自の販売ルートがあるため買取価格にも自信あり。是非一度、T-UPのサイトをご覧下さい。

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