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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/03/24 17:46:10」(JST)
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A tuberculoma is a clinical manifestation of tuberculosis which conglomerates tubercles into a firm lump, and so can mimic cancer tumors of many types in medical imaging studies.[1][2][3] Since these are evolutions of primary complex, the tuberculomas may contain within caseum or calcifications.
General
With the passage of time Mycobacterium tuberculosis (also called Bacillus Koch) can transform into crystals of calcium. These can affect any organ such as the brain,[4][5] intestine,[6] ovaries,[7][8] breast,[9][10][11] lungs,[12][13][14] esophagus,[15] intestine,[16][17] liver,[18] pancreas,[citation needed] bones,[19][20] and many others.
As the histologic and clinical indications, as well as tumor markers such as the CA-125, are similar, it is often difficult to differentiate tuberculoma from cancer. For these reasons, tuberculosis should always be considered in the differential diagnosis of cancer.
References
- ^ Pitlik SD, Fainstein V, Bodey GP; Fainstein; Bodey (May 1984). "Tuberculosis mimicking cancer--a reminder". The American Journal of Medicine 76 (5): 822–5. doi:10.1016/0002-9343(84)90993-8. PMID 6720729.
- ^ Vento S, Lanzafame M; Lanzafame (June 2011). "Tuberculosis and cancer: a complex and dangerous liaison". The Lancet Oncology 12 (6): 520–2. doi:10.1016/S1470-2045(11)70105-X. PMID 21624773.
- ^ Broxmeyer L (2004). "Is cancer just an incurable infectious disease?". Medical Hypotheses 63 (6): 986–96. doi:10.1016/j.mehy.2004.05.008. PMID 15504566.
- ^ Dennison P, Rajakaruna G; Rajakaruna (October 2006). "Cerebral tuberculoma". Thorax 61 (10): 922. doi:10.1136/thx.2005.054932. PMC 2104774. PMID 17008487.
- ^ Chatterjee S (October 2011). "Brain tuberculomas, tubercular meningitis, and post-tubercular hydrocephalus in children". Journal of Pediatric Neurosciences 6 (Suppl 1): S96–S100. doi:10.4103/1817-1745.85725. PMC 3208909. PMID 22069437.
- ^ Herrick FC (April 1925). "Tuberculoma of the Caecum: Hyperplastic Tuberculosis". Annals of Surgery 81 (4): 801–20. doi:10.1097/00000658-192504000-00009. PMC 1399989. PMID 17865239.
- ^ Elmore RG, Li AJ; Li (December 2007). "Peritoneal tuberculosis mimicking advanced-stage epithelial ovarian cancer". Obstetrics and Gynecology 110 (6): 1417–9. doi:10.1097/01.AOG.0000295653.32975.4a. PMID 18055741.
- ^ Rabesalama S, Mandeville K, Raherison R, Rakoto-Ratsimba H; Mandeville; Raherison; Rakoto-Ratsimba (2011). "Isolated ovarian tuberculosis mimicking ovarian carcinoma: case report and literature review". African Journal of Infectious Diseases 5 (1): 7–10. doi:10.4314/ajid.v5i1.66508. PMC 3497843. PMID 23878702.
- ^ Baharoon S (July 2008). "Tuberculosis of the breast". Annals of Thoracic Medicine 3 (3): 110–4. doi:10.4103/1817-1737.41918. PMC 2700437. PMID 19561892.
- ^ Sen M, Gorpelioglu C, Bozer M; Gorpelioglu; Bozer (2009). "Isolated primary breast tuberculosis: report of three cases and review of the literature". Clinics 64 (6): 607–10. doi:10.1590/S1807-59322009000600019. PMC 2705158. PMID 19578668.
- ^ Akçay MN, Sağlam L, Polat P, Erdoğan F, Albayrak Y, Povoski SP; Sağlam; Polat; Erdoğan; Albayrak; Povoski (2007). "Mammary tuberculosis -- importance of recognition and differentiation from that of a breast malignancy: report of three cases and review of the literature". World Journal of Surgical Oncology 5: 67. doi:10.1186/1477-7819-5-67. PMC 1910599. PMID 17577397.
- ^ Liang HY, Li XL, Yu XS et al. (December 2009). "Facts and fiction of the relationship between preexisting tuberculosis and lung cancer risk: a systematic review". International Journal of Cancer 125 (12): 2936–44. doi:10.1002/ijc.24636. PMID 19521963.
- ^ Liang HY, Li XL, Yu XS et al. (December 2009). "Facts and fiction of the relationship between preexisting tuberculosis and lung cancer risk: a systematic review". International Journal of Cancer 125 (12): 2936–44. doi:10.1002/ijc.24636. PMID 19521963.
- ^ Khan AN, Al-Jahdali HH, Allen CM, Irion KL, Al Ghanem S, Koteyar SS; Al-Jahdali; Allen; Irion; Al Ghanem; Koteyar (April 2010). "The calcified lung nodule: What does it mean?". Annals of Thoracic Medicine 5 (2): 67–79. doi:10.4103/1817-1737.62469. PMC 2883201. PMID 20582171.
- ^ Patnayak R, Reddy MK, Parthasarathy S, Yootla M, Reddy V, Jena A; Reddy; Parthasarathy; Yootla; Reddy; Jena (April 2008). "Unusual presentation of esophageal tuberculosis mimicking malignancy". Saudi Journal of Gastroenterology 14 (2): 103–4. doi:10.4103/1319-3767.39632. PMC 2702907. PMID 19568514.
- ^ Chakravartty S, Chattopadhyay G, Ray D, Choudhury CR, Mandal S; Chattopadhyay; Ray; Choudhury; Mandal (2010). "Concomitant tuberculosis and carcinoma colon: coincidence or causal nexus?". Saudi Journal of Gastroenterology 16 (4): 292–4. doi:10.4103/1319-3767.70619. PMC 2995101. PMID 20871197.
- ^ Kushwaha JK, Sonkar AA, Saraf A, Singh D, Gupta R; Sonkar; Saraf; Singh; Gupta (September 2011). "Jejunal adenocarcinoma: an elusive diagnosis". Indian Journal of Surgical Oncology 2 (3): 197–201. doi:10.1007/s13193-011-0101-7. PMC 3272177. PMID 22942611.
- ^ Hafezi Ahmadi M, Teimouri H, Alizadeh S; Teimouri; Alizadeh (May 2013). "The liver Metastatic Adenocarcinoma of Colorectal Cancer With Synchronous Isolated Hepatic Tuberculosis". Hepatitis Monthly 13 (5): e9844. doi:10.5812/hepatmon.9844. PMC 3741692. PMID 23967026.
- ^ Herzog A (September 2009). "Dangerous errors in the diagnosis and treatment of bony tuberculosis". Deutsches Ärzteblatt International 106 (36): 573–7. doi:10.3238/arztebl.2009.0573 (inactive 2015-02-01). PMC 2770211. PMID 19890413.
- ^ Dhillon MS, Aggarwal S, Prabhakar S, Bachhal V; Aggarwal; Prabhakar; Bachhal (March 2012). "Tuberculosis of the foot: An osteolytic variety". Indian Journal of Orthopaedics 46 (2): 206–11. doi:10.4103/0019-5413.93683. PMC 3308663. PMID 22448060.
UpToDate Contents
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- 1. 中枢神経系結核 central nervous system tuberculosis
- 2. 肺結核の臨床症状および評価 clinical manifestations and evaluation of pulmonary tuberculosis
- 3. 肺外結核および粟粒結核の臨床症状、診断、および治療 clinical manifestations diagnosis and treatment of extrapulmonary and miliary tuberculosis
- 4. 嚢虫症の臨床症状および診断 clinical manifestations and diagnosis of cysticercosis
- 5. HIV感染患者における肺結核の治療 treatment of pulmonary tuberculosis in the hiv infected patient
English Journal
- Concurrent Intramedullary and Intracerebral Tuberculoma.
- Goel A1, Sharma S2, Jain P3, Kumar A4, Aneja S5.
- Indian journal of pediatrics.Indian J Pediatr.2016 Feb;83(2):187-8. doi: 10.1007/s12098-015-1820-5. Epub 2015 Jul 5.
- PMID 26141548
- Cerebral tuberculoma with pulmonary tuberculosis in a patient with psoriasis treated with adalimumab, an anti-tumor necrosis factor-α agent.
- Selvarajah L1, Choon SE2, Tarekh NA3, Chhetri AD4.
- International journal of dermatology.Int J Dermatol.2016 Feb;55(2):e115-7. doi: 10.1111/ijd.13047. Epub 2015 Nov 13.
- PMID 26566776
- Intramedullary tuberculoma combined with abscess: a case report and literature review.
- Liu J, Zhang H, He B, Wang B, Niu X, Hao D.
- World neurosurgery.World Neurosurg.2016 Jan 21. pii: S1878-8750(16)00101-7. doi: 10.1016/j.wneu.2016.01.021. [Epub ahead of print]
- BACKGROUND: Intramedullary spinal tuberculoma combined with abscess has low incidence and could easily be misdiagnosed. Given the rarity of spinal intramedullary tuberculoma, there is no standardized treatment protocol for this condition. We reported a case of a 28-year-old male who was diagnosed wi
- PMID 26805697
Japanese Journal
- 研究・症例 抗結核薬による溶血性貧血を背景とする肺結核腫が再燃した1例
- 日本胸部臨床 = The Japanese journal of chest diseases 75(12), 1372-1376, 2016-12
- NAID 40021019420
- 結核性ぶどう膜炎 (特集 見逃してはいけない ぶどう膜炎の診療ガイド)
Related Links
- tuberculoma [too-ber″ku-lo´mah] a tumorlike mass resulting from aggregation or enlargement of caseated tubercles. tu·ber·cu·lo·ma (tū-ber'kyū-lō'mă), A rounded tumorlike but nonneoplastic mass, usually in the lungs or brain, due to ...
- Tuberculomas or tuberculous granulomas are a well defined focal mass that results from Mycobacterium tuberculosis infection, and is one of several morphological forms of tuberculous disease. Tuberculomas occur most commonly in ...
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