trepibutone

トレピブトン


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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2013/02/13 00:17:24」(JST)

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English Journal

  • pH-independent controlled-release microspheres using polyglycerol esters of fatty acids.
  • Akiyama Y, Yoshioka M, Horibe H, Hirai S, Kitamori N, Toguchi H.SourceDDS Research Laboratories, Takeda Chemical Industries, Ltd., Osaka, Japan.
  • Journal of pharmaceutical sciences.J Pharm Sci.1994 Nov;83(11):1600-7.
  • The release of a drug having low solubility in a certain pH range from controlled-release microspheres using tetraglycerol pentastearate and tetraglycerol monostearate in combination as the matrix base showed pH dependence. Trepibutone, an acidic drug having lower solubility in an acidic medium, was
  • PMID 7891282

Japanese Journal

  • ROLE OF AN INTRACELLULAR Ca STORE IN TREPIBUTONE (AA-149)-INDUCED RELAXATION OF THE DEPOLARIZED SMOOTH MUSCLE OF THE GUINEA-PIG TAENIA COLI
  • SATOH Hiroshi,INADA Ikuko,MAKI Yoshitaka
  • The Japanese Journal of Pharmacology 31(4), 593-599, 1981
  • Trepibutone, a newly synthesized smooth muscle relaxant, given before CaCl<SUB>2</SUB> … The CCh contraction was enhanced after inhibition of the Ca contracture by trepibutone. … The inhibitory effect of trepibutone on the Ca contracture was markedly reduced in the presence of CCh, whereas that of D-600 was not affected. …
  • NAID 130000835649
  • RELAXING ACTION OF TREPIBUTONE (AA-149) ON THE ISOLATED SPHINCTER OF ODDI AND SMALL INTESTINE OF RABBITS
  • SATOH Hiroshi,INADA Ikuko,MAKI Yoshitaka
  • The Japanese Journal of Pharmacology 31(4), 587-592, 1981
  • … We investigated the smooth muscle relaxing action of trepibutone [3-(2, 4, 5-triethoxybenzoyl)pro pi onic acid: AA-149] using assays of the isolated preparations of sphincter of Oddi, duodenum, jejunum and ileum of rabbits. … Trepibutone (10<SUP>-6</SUP>-10<SUP>-3</SUP> … The actions of trepibutone were not altered by pretreatment with tetrodotoxin, phentolamine or propranolol. …
  • NAID 130000835648
  • 慢性再発性膵炎に対するAA-149(trepibutone)の臨床的検討

Related Links

Trepibutone. From Wikipedia, the free encyclopedia. Jump to: navigation, search. Trepibutone. Systematic (IUPAC) name ... Trepibutone is a drug used for functional gastrointestinal disorders. v · t · e. Drugs for functional gastrointestinal ...


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