トランスフォーミング増殖因子β
- 同
- TGF-β
WordNet
- cultivate by growing, often involving improvements by means of agricultural techniques; "The Bordeaux region produces great red wines"; "They produce good ham in Parma"; "We grow wheat here"; "We raise hogs here" (同)raise, farm, produce
- come to have or undergo a change of (physical features and attributes); "He grew a beard"; "The patient developed abdominal pains"; "I got funny spots all over my body"; "Well-developed breasts" (同)develop, produce, get, acquire
- become attached by or as if by the process of growth; "The tree trunks had grown together"
- become larger, greater, or bigger; expand or gain; "The problem grew too large for me"; "Her business grew fast"
- cause to grow or develop; "He grows vegetables in his backyard"
- increase in size by natural process; "Corn doesnt grow here"; "In these forests, mushrooms grow under the trees"; "her hair doesnt grow much anymore"
- (biology) the process of an individual organism growing organically; a purely biological unfolding of events involved in an organism changing gradually from a simple to a more complex level; "he proposed an indicator of osseous development in children" (同)growing, maturation, development, ontogeny, ontogenesis
- (pathology) an abnormal proliferation of tissue (as in a tumor)
- a progression from simpler to more complex forms; "the growth of culture"
- something grown or growing; "a growth of hair"
- vegetation that has grown; "a growth of trees"; "the only growth was some salt grass"
- be a contributing factor; "make things factor into a companys profitability"
- any of the numbers (or symbols) that form a product when multiplied together
- an independent variable in statistics
- anything that contributes causally to a result; "a number of factors determined the outcome"
- consider as relevant when making a decision; "You must factor in the recent developments" (同)factor in, factor out
- resolve into factors; "a quantum computer can factor the number 15" (同)factor in, factor out
- an event known to have happened or something known to have existed; "your fears have no basis in fact"; "how much of the story is fact and how much fiction is hard to tell"
- a concept whose truth can be proved; "scientific hypotheses are not facts"
- a piece of information about circumstances that exist or events that have occurred; "first you must collect all the facts of the case"
- a statement or assertion of verified information about something that is the case or has happened; "he supported his argument with an impressive array of facts"
PrepTutorEJDIC
- 『成長する』,育つ,〈植物が〉生える,茂る / (類・量・程などにおいて)『増大する』,大きくなる / 『しだいになる』 / …‘を'成長させる,大きくする,育てる / …から生じる(起こる)
- 〈U〉(…の)『成長』,発育;『発達』,発展《+『of』+『名』》 / 〈U〉(数・量,重要性・力などの)『増加』,増大,拡張《+『of』+『名』》 / 〈U〉《修飾語[句]を伴って》栽培,生産,…産 / 〈C〉成育した物,(草,木,髪,ひげなどの)生えたもの / 〈C〉腫瘍(しゅよう)
- (…の)『要因』,(…を生み出す)要素《+『in』+『名』(do『ing』)》 / 囲数,約数 / 代理人,《おもに英》仲買人 / =factorize
- 〈C〉『事実』,実際にある(あった)事 / 〈U〉真相,真実(truth) / 《the~》(法律用語で)犯行
UpToDate Contents
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Japanese Journal
- In Vivo Hair Growth-Promoting Effect of Rice Bran Extract Prepared by Supercritical Carbon Dioxide Fluid
- Choi Jae-Suk,Jeon Min-Hee,Moon Woi-Sook [他],Moon Jin-Nam,Cheon Eun Jin,Kim Joo-Wan,Jung Sung Kyu,Ji Yi-Hwa,Son Sang Wook,Kim Mi-Ryung
- Biological and Pharmaceutical Bulletin 37(1), 44-53, 2014
- … The potential hair growth-promoting activity of rice bran supercritical CO2 extract (RB-SCE) and major components of RB-SCE, linoleic acid, policosanol, γ-oryzanol, and γ-tocotrienol, were evaluated with the histological morphology and mRNA expression levels of cell growth factors using real-time reverse transcriptase-polymerase chain reaction (PCR) in C57BL/6 mice. …
- NAID 130003382096
- Loss of SMAD4 From Colorectal Cancer Cells Promotes CCL15 Expression to Recruit CCR1(+) Myeloid Cells and Facilitate Liver Metastasis.
- Itatani Yoshiro,Kawada Kenji,Fujishita Teruaki,Kakizaki Fumihiko,Hirai Hideyo,Matsumoto Takuya,Iwamoto Masayoshi,Inamoto Susumu,Hatano Etsuro,Hasegawa Suguru,Maekawa Taira,Uemoto Shinji,Sakai Yoshiharu,Taketo Makoto Mark
- Gastroenterology 145(5), 1064-1075.e11, 2013-11
- … transforming growth factor-β increased binding of SMAD4 to the CCL15 promoter and transcriptional repression. …
- NAID 120005348333
- 肺線維症治療薬開発の向かうべき方向 (特集 肺線維症治療薬の現況)
Related Links
- トランスフォーミング増殖因子-β1(Transforming Growth Factor-β1:TGF-β1) トランスフォーミング増殖因子-β(TGF-β)は、当初、線維芽細胞の形質転換を促進する因子として見出され命名されたが、現在では多くの細胞に対してむしろ強力な ...
- Fibrillin-1 also has motifs with homology to latent transforming growth factor-β–binding proteins. Fibrillin-1 proteins aggregate and associate to form microfibrils, which are important structural components of elastic In addition to 5 ...
Related Pictures
★リンクテーブル★
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- 英
- transforming growth factor β, transforming growth factor-β、TGFβ, TGF-β
- 同
- トランスフォーミング成長因子
- 関
- TGF
- stimulatory: cells of mesenchymal origin
- inhibitory: cells of epithelial or neuroectodermal origin
- important mediator of the formation of extracellular matrix
- 細胞内のシグナル系にSmadが関与。セリン・スレオニンキナーゼ連結受容体型の受容体
- EGF, IFN-γ, TNF-αの細胞内情報伝達経路とクロストークする
産生細胞
機能
- 細胞の成長阻害、抗炎症作用、IgAへのクラススイッチ
受容体
- TGFβR
- type I受容体とtype II受容体が一つのサブユニットを作り、このサブユニットがホモ二量体を形成してTGFβの受容体を形成している
- TGFβ毛結合した受容体は活性化してSmad2/Smad3をリン酸化する
- リン酸化されたSmad2/Smad3はSmad4と結合して核移行しDNAに結合して転写を促進する
[★]
- (過去: grew-過去分詞: grown)
- 関
- extend、growth、outgrow、outgrowth、stretch
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- 関
- actual、actually、in fact、in practice、indeed、practically
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- 関
- element、elementary、factorial、parameter
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- 関
- transform、transformation、transgenic
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