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English Journal

Norn S, Kruse PR, Kruse E.
Dansk medicinhistorisk årbog.Dan Medicinhist Arbog.2005;33:171-84.
Opium has been known for millennia to relieve pain and its use for surgical analgesia has been recorded for several centuries. The Sumerian clay tablet (about 2100 BC) is considered to be the world's oldest recorded list of medical prescriptions. It is believed by some scholars that the opium poppy
PMID 17152761

[Methadone treatment during pregnancy and its effect on the child. Better than continuing drug abuse, should be monitored by a specialized antenatal care center].

Sarman I1.
Läkartidningen.Lakartidningen.2000 May 3;97(18):2182-4, 2187-8, 2190.
Observations concerning methadone treatment in 21 pregnancies of drug addicted women in Stockholm between 1982 and 1997 are presented. Fourteen per cent of new-born infants were small for gestational age, with head circumference less than--2 SD. None had congenital malformations, but neonatal abstin
PMID 10850047

[Treatment with clonidine in a case of the short bowel syndrome with therapy-refractory diarrhea].

Scholz J1, Bause H, Reymann A, Dürig M.
Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS.Anasthesiol Intensivmed Notfallmed Schmerzther.1991 Aug;26(5):265-9.
A patient with refractory diarrhoea (up to 10 l/d) following colectomy and ileostomy was treated with clonidine, after loperamide, tinctura opii, cholestyramine and somatostatin had failed to reduce stool volume to less than 6 l/d. Under combined treatment with clonidine (1200 micrograms/d) and soma
PMID 1681951