adj.

視床の

関: thalami、thalamo、thalamus

WordNet

large egg-shaped structures of grey matter that form the dorsal subdivision of the diencephalon
of or relating to the cortex and the hypothalamus

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/04/03 10:10:49」(JST)

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The thalamus (from Greek θάλαμος, "chamber")^[1] is a midline symmetrical structure of two halves, within the vertebrate brain, situated between the cerebral cortex and the midbrain. Some of its functions are the relaying of sensory and motor signals to the cerebral cortex,^[2]^[3] and the regulation of consciousness, sleep, and alertness. The two parts of the thalamus surround the third ventricle. It is the main product of the embryonic diencephalon.

1 Anatomy
- 1.1 Morphology
- 1.2 Blood supply
- 1.3 Thalamic nuclei
- 1.4 Connections
2 Function
3 Development
- 3.1 Early brain development
- 3.2 The formation of the mid-diencephalic organiser (MDO)
- 3.3 Maturation and parcellation of the thalamus
4 Clinical significance
5 Additional images
6 See also
7 References
8 External links

Anatomy

The thalamus in a 360° rotation

The thalamus is located in the forebrain superior to the midbrain, near the center of the brain, with nerve fibers projecting out to the cerebral cortex in all directions. The medial surface of the thalamus constitutes the upper part of the lateral wall of the third ventricle, and is connected to the corresponding surface of the opposite thalamus by a flattened gray band, the interthalamic adhesion.

Morphology

The two halves of the thalamus are prominent bulb-shaped masses, about 5.7 cm in length, located obliquely (about 30°) and symmetrically on each side of the third ventricle^{[clarification needed]}. Both parts of the thalamus, in the human, are about the size and shape of a walnut.^[2] These are about three centimetres in length, at the widest part 2.5 centimetres across and about 2 centimetres in height (comparable to an unshelled walnut, with the nut-shell joining in the horizontal plane).

Blood supply

The thalamus derives its blood supply from a number of arteries: the polar artery (posterior communicating artery), paramedian thalamic-subthalamic arteries, inferolateral (thalamogeniculate) arteries, and posterior (medial and lateral) choroidal arteries.^[4] These are all branches of the posterior cerebral artery.^[5]

Some people have the artery of Percheron, which is a rare anatomic variation in which a single arterial trunk arises from the posterior cerebral artery to supply both parts of the thalamus.

Thalamic nuclei

Nuclei of the thalamus

The thalamus is part of a nuclear complex structured of four parts, the hypothalamus, epithalamus, prethalamus (formerly called ventral thalamus), and dorsal thalamus.^[6]

Derivatives of the diencephalon also include the dorsally-located epithalamus (essentially the habenula and annexes) and the perithalamus (prethalamus) containing the zona incerta and the thalamic reticular nucleus. Due to their different ontogenetic origins, the epithalamus and the perithalamus are formally distinguished from the thalamus proper.

The thalamus comprises a system of lamellae (made up of myelinated fibers) separating different thalamic subparts. Other areas are defined by distinct clusters of neurons, such as the periventricular nucleus, the intralaminar elements, the "nucleus limitans", and others.^[7] These latter structures, different in structure from the major part of the thalamus, have been grouped together into the allothalamus as opposed to the isothalamus.^[8] This distinction simplifies the global description of the thalamus.

Connections

The thalamus is connected to the spinal cord via the spinothalamic tract.

The thalamus is manifoldly connected to the hippocampus via the mammillo-thalamic tract, this tract comprises the mammilary body and fornix.^[9]

The thalamus is connected to the cerebral cortex via the thalamocortical radiations.^[10]

The spinothalamic tract is a sensory pathway originating in the spinal cord. It transmits information to the thalamus about pain, temperature, itch and crude touch. There are two main parts: the lateral spinothalamic tract, which transmits pain and temperature, and the anterior (or ventral) spinothalamic tract, which transmits crude touch and pressure.

Function

The thalamus has multiple functions. It may be thought of as a kind of hub of information. It is generally believed to act as a relay between different subcortical areas and the cerebral cortex. In particular, every sensory system (with the exception of the olfactory system) includes a thalamic nucleus that receives sensory signals and sends them to the associated primary cortical area. For the visual system, for example, inputs from the retina are sent to the lateral geniculate nucleus of the thalamus, which in turn projects to the visual cortex in the occipital lobe. The thalamus is believed to both process sensory information as well as relay it—each of the primary sensory relay areas receives strong feedback connections from the cerebral cortex. Similarly the medial geniculate nucleus acts as a key auditory relay between the inferior colliculus of the midbrain and the primary auditory cortex, and the ventral posterior nucleus is a key somatosensory relay, which sends touch and proprioceptive information to the primary somatosensory cortex.

The thalamus also plays an important role in regulating states of sleep and wakefulness.^[11] Thalamic nuclei have strong reciprocal connections with the cerebral cortex, forming thalamo-cortico-thalamic circuits that are believed to be involved with consciousness. The thalamus plays a major role in regulating arousal, the level of awareness, and activity. Damage to the thalamus can lead to permanent coma.

The role of the thalamus in the more anterior pallidal and nigral territories in the basal ganglia system disturbances is recognized but still poorly understood. The contribution of the thalamus to vestibular or to tectal functions is almost ignored. The thalamus has been thought of as a "relay" that simply forwards signals to the cerebral cortex. Newer research suggests that thalamic function is more selective.^[12] Many different functions are linked to various regions of the thalamus. This is the case for many of the sensory systems (except for the olfactory system), such as the auditory, somatic, visceral, gustatory and visual systems where localized lesions provoke specific sensory deficits. A major role of the thalamus is devoted to "motor" systems. The thalamus is functionally connected to the hippocampus^[13] as part of the extended hippocampal system at the thalamic anterior nuclei^[14] with respect to spatial memory and spatial sensory datum they are crucial for human episodic memory and rodent event memory.^[15]^[16] There is support for the hypothesis that thalamic regions connection to particular parts of the mesio-temporal lobe provide differentiation of the functioning of recollective and familiarity memory.^[9]

The neuronal information processes necessary for motor control were proposed as a network involving the thalamus as a subcortical motor centre.^[17] Through investigations of the anatomy of the brains of primates^[18] the nature of the interconnected tissues of the cerebellum to the multiple motor cortices suggested that the thalamus fulfills a key function in providing the specific channels from the basal ganglia and cerebellum to the cortical motor areas.^[19]^[20] In an investigation of the saccade and antisaccade^[21] motor response in three monkeys, the thalamic regions were found to be involved in the generation of antisaccade eye-movement.^[22]

Development

The thalamic complex is composed of the perithalamus (or prethalamus, previously also known as ventral thalamus), the mid-diencephalic organiser (which forms later the zona limitans intrathalamica (ZLI) ) and the thalamus (dorsal thalamus).^[23]^[24] The development of the thalamus can be subdivide into three steps^[25] The thalamus is the largest structure deriving from the embryonic diencephalon, the posterior part of the forebrain situated between the midbrain and the cerebrum.

Early brain development

After neurulation the anlage of the prethalamus and the thalamus is induced within the neural tube. Data from different vertebrate model organisms support a model in which the interaction between two transcription factors, Fez and Otx, are of decisive importance. Fez is expressed in the prethalamus, and functional experiments show that Fez is required for prethalamus formation.^[26]^[27] Posteriorly, Otx1 and Otx2 abut the expression domain of Fez and are required for proper development of the thalamus.^[28]^[29]

The formation of the mid-diencephalic organiser (MDO)

At the interface between the expression domains of Fez and Otx, the mid-diencephalic organizer (MDO, also called the ZLI organiser) is induced within the thalamic anlage. The MDO is the central signalling organizer in the thalamus. A lack of the organizer leads to the absence of the thalamus. The MDO matures from ventral to dorsal during development. Members of the SHH family and of the Wnt family are the main principal signals emitted by the MDO.

Besides its importance as signalling center, the organizer matures into the morphological structure of the zona limitans intrathalamica (ZLI).

Maturation and parcellation of the thalamus

After its induction, the MDO starts to orchestrate the development of the thalamic anlage by release of signalling molecules such as SHH.^[30] In mice, the function of signaling at the MDO has not been addressed directly due to a complete absence of the diencephalon in SHH mutants.^[31]

Studies in chicks have shown that SHH is both necessary and sufficient for thalamic gene induction.^[32] In zebrafish, it was shown that the expression of two SHH genes, SHH-a and SHH-b (formerly described as twhh) mark the MDO territory, and that SHH signaling is sufficient for the molecular differentiation of both the prethalamus and the thalamus but is not required for their maintenance and SHH signaling from the MDO/alar plate is sufficient for the maturation of prethalamic and thalamic territory while ventral Shh signals are dispensable.^[33]

The exposure to SHH leads to differentiation of thalamic neurons. SHH signaling from the MDO induces a posterior-to-anterior wave of expression the proneural gene Neurogenin1 in the major (caudal) part of the thalamus, and Ascl1 (formerly Mash1) in the remaining narrow stripe of rostral thalamic cells immediately adjacent to the MDO, and in the prethalamus.^[34]^[35]

This zonation of proneural gene expression leads to the differentiation of glutamatergic relay neurons from the Neurogenin1+ precursors and of GABAergic inhibitory neurons from the Ascl1+ precursors. In fish, selection of these alternative neurotransmitter fates is controlled by the dynamic expression of Her6 the homolog of HES1. Expression of this hairy-like bHLH transcription factor, which represses Neurogenin but is required for Ascl1, is progressively lost from the caudal thalamus but maintained in the prethalamus and in the stripe of rostral thalamic cells. In addition, studies on chick and mice have shown that blocking the Shh pathway leads to absence of the rostral thalamus and substantial decrease of the caudal thalamus. The rostral thalamus will give rise to the reticular nucleus mainly whereby the caudal thalamus will form the relay thalamus and will be further subdivided in the thalamic nuclei.^[25]

In humans, a common genetic variation in the promotor region of the serotonin transporter (the SERT-long and -short allele: 5-HTTLPR) has been shown to affect the development of several regions of the thalamus in adults. People who inherit two short alleles (SERT-ss) have more neurons and a larger volume in the pulvinar and possibly the limbic regions of the thalamus. Enlargement of the thalamus provides an anatomical basis for why people who inherit two SERT-ss alleles are more vulnerable to major depression, posttraumatic stress disorder, and suicide.^[36]

Clinical significance

A cerebrovascular accident (stroke) can lead to the thalamic syndrome,^[37] which involves a one-sided burning or aching sensation often accompanied by mood swings. Bilateral ischemia of the area supplied by the paramedian artery can cause serious problems including akinetic mutism, and be accompanied by oculomotor problems. A related concept is thalamocortical dysrhythmia. The occlusion of the artery of Percheron can lead to a bilateral thalamus infarction.

Korsakoff's syndrome stems from damage to the mammillary body, the mammillothalamic fasciculus or the thalamus.

Fatal familial insomnia is a hereditary prion disease in which degeneration of the thalamus occurs, causing the patient to gradually lose his ability to sleep and progressing to a state of total insomnia, which invariably leads to death. In contrast, damage to the thalamus can result in coma.

Additional images

Images are circa 1858.^[38]

The left optic nerve and the optic tracts.
Coronal section of lateral and 3rd ventricles.
Dissection showing the ventricles of the brain.
Section of brain showing upper surface of temporal lobe.
Horizontal section of right cerebral hemisphere.
Mesal aspect of a brain sectioned in the median sagittal plane.
Schematic representation of the chief ganglionic categories (I to V).
Scheme showing the course of the fibers of the lemniscus; medial lemniscus in blue, lateral in red.
Deep dissection of brain-stem. Lateral view.
Deep dissection of brain-stem. Ventral view.
Coronal section of brain immediately in front of pons.
Coronal section of brain through intermediate mass of third ventricle.
Human brain frontal (coronal) section
Thalamus
Ventricles of brain and basal ganglia. Superior view. Horizontal section. Deep dissection
Ventricles of brain and basal ganglia. Superior view. Horizontal section. Deep dissection

References

^ Harper - index & University of Washington Faculty Web Server & Search engine search page + Perseus Project tufts.edu Retrieved 2012-02-09
^ ^a ^b Sherman, S. (2006). "Thalamus". Scholarpedia 1 (9): 1583. doi:10.4249/scholarpedia.1583.
^ Sherman, S. Murray; Guillery, R. W. (2000). Exploring the Thalamus. Academic Press. ISBN 978-0-12-305460-9. ^{[page needed]}
^ Percheron, G. (1982). "The arterial supply of the thalamus". In Schaltenbrand; Walker, A. E. Stereotaxy of the human brain. Stuttgart: Thieme. pp. 218–32.
^ Knipe, H Jones, J et al. Thalamus http://radiopaedia.org/articles/thalamus
^ Herrero, María-Trinidad; Barcia, Carlos; Navarro, Juana (2002). "Functional anatomy of thalamus and basal ganglia". Child's Nervous System 18 (8): 386. doi:10.1007/s00381-002-0604-1.
^ Jones Edward G.(2007) "The Thalamus" Cambridge Uni. Press^{[page needed]}
^ Percheron, G. (2003). "Thalamus". In Paxinos, G.; May, J. The human nervous system (2nd ed.). Amsterdam: Elsevier. pp. 592–675.
^ ^a ^b Carlesimo, GA; Lombardi, MG; Caltagirone, C (2011). "Vascular thalamic amnesia: A reappraisal". Neuropsychologia 49 (5): 777–89. doi:10.1016/j.neuropsychologia.2011.01.026. PMID 21255590.
^ University of Washington (1991). "Thalamocortical radiations". washington.edu.
^ Steriade, Mircea; Llinás, Rodolfo R. (1988). "The Functional States of the Thalamus and the Associated Neuronal Interplay". Physiological Reviews 68 (3): 649–742. PMID 2839857.
^ Leonard, Abigail W. (August 17, 2006). "Your Brain Boots Up Like a Computer". LiveScience.
^ Stein, Thor; Moritz, Chad; Quigley, Michelle; Cordes, Dietmar; Haughton, Victor; Meyerand, Elizabeth (2000). "Functional Connectivity in the Thalamus and Hippocampus Studied with Functional MR Imaging". American Journal of Neuroradiology 21 (8): 1397–401. PMID 11003270.
^ Aggleton, John P.; Brown, Malcolm W. (1999). "Episodic memory, amnesia, and the hippocampal–anterior thalamic axis". Behavioral and Brain Sciences 22 (3): 425–44; discussion 444–89. doi:10.1017/S0140525X99002034. PMID 11301518.
^ Aggleton, John P.; O'Mara, Shane M.; Vann, Seralynne D.; Wright, Nick F.; Tsanov, Marian; Erichsen, Jonathan T. (2010). "Hippocampal-anterior thalamic pathways for memory: Uncovering a network of direct and indirect actions". European Journal of Neuroscience 31 (12): 2292–307. doi:10.1111/j.1460-9568.2010.07251.x. PMC 2936113. PMID 20550571.
^ Burgess, Neil; Maguire, Eleanor A; O'Keefe, John (2002). "The Human Hippocampus and Spatial and Episodic Memory". Neuron 35 (4): 625–41. doi:10.1016/S0896-6273(02)00830-9. PMID 12194864.
^ Evarts, E V; Thach, W T (1969). "Motor Mechanisms of the CNS: Cerebrocerebellar Interrelations". Annual Review of Physiology 31: 451–98. doi:10.1146/annurev.ph.31.030169.002315. PMID 4885774.
^ Orioli, PJ; Strick, PL (1989). "Cerebellar connections with the motor cortex and the arcuate premotor area: An analysis employing retrograde transneuronal transport of WGA-HRP". The Journal of comparative neurology 288 (4): 612–26. doi:10.1002/cne.902880408. PMID 2478593.
^ Asanuma C, Thach WT, Jones EG (May 1983). "Cytoarchitectonic delineation of the ventral lateral thalamic region in the monkey". Brain Research 286 (3): 219–35. doi:10.1016/0165-0173(83)90014-0. PMID 6850357.
^ Kurata, K (2005). "Activity properties and location of neurons in the motor thalamus that project to the cortical motor areas in monkeys". Journal of neurophysiology 94 (1): 550–66. doi:10.1152/jn.01034.2004. PMID 15703228.
^ http://www.optomotorik.de/blicken/anti-rev.htm^{[full citation needed]}
^ Kunimatsu, J; Tanaka, M (2010). "Roles of the primate motor thalamus in the generation of antisaccades". The Journal of neuroscience 30 (14): 5108–17. doi:10.1523/JNEUROSCI.0406-10.2010. PMID 20371831.
^ Kuhlenbeck, Hartwig (1937). "The ontogenetic development of the diencephalic centers in a bird's brain (chick) and comparison with the reptilian and mammalian diencephalon". The Journal of Comparative Neurology 66: 23. doi:10.1002/cne.900660103.
^ Shimamura, K; Hartigan, DJ; Martinez, S; Puelles, L; Rubenstein, JL (1995). "Longitudinal organization of the anterior neural plate and neural tube". Development 121 (12): 3923–33. PMID 8575293.
^ ^a ^b Scholpp, Steffen; Lumsden, Andrew (2010). "Building a bridal chamber: Development of the thalamus". Trends in Neurosciences 33 (8): 373–80. doi:10.1016/j.tins.2010.05.003. PMC 2954313. PMID 20541814.
^ Hirata, T.; Nakazawa, M; Muraoka, O; Nakayama, R; Suda, Y; Hibi, M (2006). "Zinc-finger genes Fez and Fez-like function in the establishment of diencephalon subdivisions". Development 133 (20): 3993–4004. doi:10.1242/dev.02585. PMID 16971467.
^ Jeong, J.-Y.; Einhorn, Z.; Mathur, P.; Chen, L.; Lee, S.; Kawakami, K.; Guo, S. (2007). "Patterning the zebrafish diencephalon by the conserved zinc-finger protein Fezl". Development 134 (1): 127–36. doi:10.1242/dev.02705. PMID 17164418.
^ Acampora, D; Avantaggiato, V; Tuorto, F; Simeone, A (1997). "Genetic control of brain morphogenesis through Otx gene dosage requirement". Development 124 (18): 3639–50. PMID 9342056.
^ Scholpp, S.; Foucher, I.; Staudt, N.; Peukert, D.; Lumsden, A.; Houart, C. (2007). "Otx1l, Otx2 and Irx1b establish and position the ZLI in the diencephalon". Development 134 (17): 3167–76. doi:10.1242/dev.001461. PMID 17670791.
^ Puelles, L; Rubenstein, JL (2003). "Forebrain gene expression domains and the evolving prosomeric model". Trends in neurosciences 26 (9): 469–76. doi:10.1016/S0166-2236(03)00234-0. PMID 12948657.
^ Ishibashi, M; McMahon, AP (2002). "A sonic hedgehog-dependent signaling relay regulates growth of diencephalic and mesencephalic primordia in the early mouse embryo". Development 129 (20): 4807–19. PMID 12361972.
^ Kiecker, C; Lumsden, A (2004). "Hedgehog signaling from the ZLI regulates diencephalic regional identity". Nature Neuroscience 7 (11): 1242–9. doi:10.1038/nn1338. PMID 15494730.
^ Scholpp, S.; Wolf, O; Brand, M; Lumsden, A (2006). "Hedgehog signalling from the zona limitans intrathalamica orchestrates patterning of the zebrafish diencephalon". Development 133 (5): 855–64. doi:10.1242/dev.02248. PMID 16452095.
^ Scholpp, S.; Delogu, A.; Gilthorpe, J.; Peukert, D.; Schindler, S.; Lumsden, A. (2009). "Her6 regulates the neurogenetic gradient and neuronal identity in the thalamus". Proceedings of the National Academy of Sciences 106 (47): 19895–900. doi:10.1073/pnas.0910894106. PMC 2775703. PMID 19903880.
^ Vue, Tou Yia; Bluske, Krista; Alishahi, Amin; Yang, Lin Lin; Koyano-Nakagawa, Naoko; Novitch, Bennett; Nakagawa, Yasushi (2009). "Sonic Hedgehog Signaling Controls Thalamic Progenitor Identity and Nuclei Specification in Mice". Journal of Neuroscience 29 (14): 4484–97. doi:10.1523/JNEUROSCI.0656-09.2009. PMC 2718849. PMID 19357274.
^ Young, Keith A.; Holcomb, Leigh A.; Bonkale, Willy L.; Hicks, Paul B.; Yazdani, Umar; German, Dwight C. (2007). "5HTTLPR Polymorphism and Enlargement of the Pulvinar: Unlocking the Backdoor to the Limbic System". Biological Psychiatry 61 (6): 813–8. doi:10.1016/j.biopsych.2006.08.047. PMID 17083920.
^ Dejerine, J.; Roussy, G. (1906). "Le syndrome thalamique". Revue Neurologique 14: 521–32.
^ Gray, H. & Carter, H. V. (1858), Anatomy Descriptive and Surgical, London: John W. Parker and Son, Retrieved (16 October 2011) [2012-02-10] → [1]

External links

Stained brain slice images which include the "thalamus" at the BrainMaps project

UpToDate Contents

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1. 感覚消失患者へのアプローチ approach to the patient with sensory loss
2. 後方循環系の脳血管症候群 posterior circulation cerebrovascular syndromes
3. ラクナ梗塞 lacunar infarcts
4. 新生児における脳卒中 stroke in the newborn
5. 特発性脳出血：病因、臨床的特徴、および診断 spontaneous intracerebral hemorrhage pathogenesis clinical features and diagnosis

English Journal

Different susceptibility of medial temporal lobe and basal ganglia atrophy rates to vascular risk factors.

de Jong LW, Forsberg LE, Vidal JS, Sigurdsson S, Zijdenbos AP, Garcia M, Eiriksdottir G, Gudnason V, van Buchem MA, Launer LJ.SourceDepartment of Radiology, Leiden University Medical Center, Leiden, the Netherlands.
Neurobiology of aging.Neurobiol Aging.2014 Jan;35(1):72-8. doi: 10.1016/j.neurobiolaging.2013.07.009. Epub 2013 Aug 28.
Atrophy of the medial temporal lobe (MTL) and basal ganglia (BG) are characteristic of various neurodegenerative diseases in older people. In search of potentially modifiable factors that lead to atrophy in these structures, we studied the association of vascular risk factors with atrophy of the MTL
PMID 23992618

Maladaptive connectivity of Broca's area in schizophrenia during audiovisual speech perception: An fMRI study.

Szycik GR, Ye Z, Mohammadi B, Dillo W, Te Wildt BT, Samii A, Frieling H, Bleich S, Münte TF.SourceDepartment of Psychiatry, Social Psychiatry and Psychotherapy, Medical School Hannover, Hanover, Germany.
Neuroscience.Neuroscience.2013 Dec 3;253:274-82. doi: 10.1016/j.neuroscience.2013.08.041. Epub 2013 Aug 30.
Speech comprehension relies on auditory as well as visual information, and is enhanced in healthy subjects, when audiovisual (AV) information is present. Patients with schizophrenia have been reported to have problems regarding this AV integration process, but little is known about which underlying
PMID 23994183

Neuropathologic studies of the encephalopathy of prematurity in the late preterm infant.

Haynes RL, Sleeper LA, Volpe JJ, Kinney HC.SourceDepartment of Pathology, Boston Children's Hospital, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA. Electronic address: Robin.haynes@childrens.harvard.edu.
Clinics in perinatology.Clin Perinatol.2013 Dec;40(4):707-22. doi: 10.1016/j.clp.2013.07.003. Epub 2013 Sep 20.
It has been widely suggested that brain damage in survivors of late preterm deliveries is similar to that in early preterm infants, only less severe. This report addresses this concept through reanalysis of published neuropathologic data obtained according to late preterm in comparison with early pr
PMID 24182957

Japanese Journal

症例病初期に髄液細胞数の上昇を認めず,MRIで前頭・頭頂・後頭葉,視床に病変を呈した単純ヘルペスウイルス脳炎の1例

澤田潤,浅野目明日香,髙橋佳恵 [他]
内科 115(1), 171-173, 2015-01
NAID 40020306134

デジタル演算回路実装に適した大脳皮質及び視床の神経細胞モデル

名波拓哉,河野崇
生産研究 67(3), 297-300, 2015
シリコン神経ネットワーク等に用いられる神経細胞モデルには，神経活動の再現性と計算効率との間にトレードオフが存在し，発展途上である．本研究では，大脳皮質及び視床に存在する4 つの神経細胞クラスを再現する多変数の神経細胞モデルに対し，次元縮約を行い3 変数モデルを導出し，分岐解析により数理構造を解析した．そして，デジタル演算回路で実装効率のよいDSSN モデルと，この3 変数モデルの数理構造が一致する …
NAID 130005074274

Visualization of Periventricular Collaterals in Moyamoya Disease with Flow-sensitive Black-blood Magnetic Resonance Angiography: Preliminary Experience

FUNAKI Takeshi,FUSHIMI Yasutaka,TAKAHASHI Jun C.,TAKAGI Yasushi,ARAKI Yoshio,YOSHIDA Kazumichi,KIKUCHI Takayuki,MIYAMOTO Susumu
Neurologia medico-chirurgica advpub(0), 2015
… It depicted abnormal collaterals as extended lenticulostriate, thalamic perforating, or choroidal arteries, which were all connected to the medullary or insular artery in the periventricular area and supplied the cortex. …
NAID 130004922313

Related Pictures

★リンクテーブル★

リンク元	「thalamo」
拡張検索	「reticular thalamic nucleus」「functional hypothalamic amenorrhea」
関連記事	「thalami」

「thalamo」

Thalamus
	thalamus marked (MRI cross-section)
	anterolateral view
Details
Latin	thalamus dorsalis
Part of	Diencephalon
Components	See List of thalamic nuclei
Artery	Posterior cerebral artery and branches
Identifiers
Gray's	p.808
MeSH	A08.186.211.730.385.826
NeuroNames	hier-283
NeuroLex ID	Thalamus
TA	A14.1.08.101; A14.1.08.601
FMA	62007
	Anatomical terms of neuroanatomy

　　[★]

視床

関: thalami、thalamic、thalamus

「reticular thalamic nucleus」

　　[★]

視床網様核

関: thalamic reticular nucleus、TRN

「functional hypothalamic amenorrhea」

　　[★] 機能性視床下部性無月経

「thalami」

　　[★]

視床

関: thalamic、thalamo、thalamus

[1] Harper - index & University of Washington Faculty Web Server & Search engine search page + Perseus Project tufts.edu Retrieved 2012-02-09

[Poetics-2] Sherman, S. (2006). "Thalamus". Scholarpedia 1 (9): 1583. doi:10.4249/scholarpedia.1583.

[3] Sherman, S. Murray; Guillery, R. W. (2000). Exploring the Thalamus. Academic Press. ISBN 978-0-12-305460-9. ^{[page needed]}

[4] Percheron, G. (1982). "The arterial supply of the thalamus". In Schaltenbrand; Walker, A. E. Stereotaxy of the human brain. Stuttgart: Thieme. pp. 218–32.

[5] Knipe, H Jones, J et al. Thalamus http://radiopaedia.org/articles/thalamus

[6] Herrero, María-Trinidad; Barcia, Carlos; Navarro, Juana (2002). "Functional anatomy of thalamus and basal ganglia". Child's Nervous System 18 (8): 386. doi:10.1007/s00381-002-0604-1.

[7] Jones Edward G.(2007) "The Thalamus" Cambridge Uni. Press^{[page needed]}

[8] Percheron, G. (2003). "Thalamus". In Paxinos, G.; May, J. The human nervous system (2nd ed.). Amsterdam: Elsevier. pp. 592–675.

[pmid21255590-9] Carlesimo, GA; Lombardi, MG; Caltagirone, C (2011). "Vascular thalamic amnesia: A reappraisal". Neuropsychologia 49 (5): 777–89. doi:10.1016/j.neuropsychologia.2011.01.026. PMID 21255590.

[10] University of Washington (1991). "Thalamocortical radiations". washington.edu.

[11] Steriade, Mircea; Llinás, Rodolfo R. (1988). "The Functional States of the Thalamus and the Associated Neuronal Interplay". Physiological Reviews 68 (3): 649–742. PMID 2839857.

[12] Leonard, Abigail W. (August 17, 2006). "Your Brain Boots Up Like a Computer". LiveScience.

[13] Stein, Thor; Moritz, Chad; Quigley, Michelle; Cordes, Dietmar; Haughton, Victor; Meyerand, Elizabeth (2000). "Functional Connectivity in the Thalamus and Hippocampus Studied with Functional MR Imaging". American Journal of Neuroradiology 21 (8): 1397–401. PMID 11003270.

[14] Aggleton, John P.; Brown, Malcolm W. (1999). "Episodic memory, amnesia, and the hippocampal–anterior thalamic axis". Behavioral and Brain Sciences 22 (3): 425–44; discussion 444–89. doi:10.1017/S0140525X99002034. PMID 11301518.

[15] Aggleton, John P.; O'Mara, Shane M.; Vann, Seralynne D.; Wright, Nick F.; Tsanov, Marian; Erichsen, Jonathan T. (2010). "Hippocampal-anterior thalamic pathways for memory: Uncovering a network of direct and indirect actions". European Journal of Neuroscience 31 (12): 2292–307. doi:10.1111/j.1460-9568.2010.07251.x. PMC 2936113. PMID 20550571.

[16] Burgess, Neil; Maguire, Eleanor A; O'Keefe, John (2002). "The Human Hippocampus and Spatial and Episodic Memory". Neuron 35 (4): 625–41. doi:10.1016/S0896-6273(02)00830-9. PMID 12194864.

[17] Evarts, E V; Thach, W T (1969). "Motor Mechanisms of the CNS: Cerebrocerebellar Interrelations". Annual Review of Physiology 31: 451–98. doi:10.1146/annurev.ph.31.030169.002315. PMID 4885774.

[18] Orioli, PJ; Strick, PL (1989). "Cerebellar connections with the motor cortex and the arcuate premotor area: An analysis employing retrograde transneuronal transport of WGA-HRP". The Journal of comparative neurology 288 (4): 612–26. doi:10.1002/cne.902880408. PMID 2478593.

[19] Asanuma C, Thach WT, Jones EG (May 1983). "Cytoarchitectonic delineation of the ventral lateral thalamic region in the monkey". Brain Research 286 (3): 219–35. doi:10.1016/0165-0173(83)90014-0. PMID 6850357.

[20] Kurata, K (2005). "Activity properties and location of neurons in the motor thalamus that project to the cortical motor areas in monkeys". Journal of neurophysiology 94 (1): 550–66. doi:10.1152/jn.01034.2004. PMID 15703228.

[21] ttp://www.optomotorik.de/blicken/anti-rev.htm^{[full citation needed]}

[22] Kunimatsu, J; Tanaka, M (2010). "Roles of the primate motor thalamus in the generation of antisaccades". The Journal of neuroscience 30 (14): 5108–17. doi:10.1523/JNEUROSCI.0406-10.2010. PMID 20371831.

[23] Kuhlenbeck, Hartwig (1937). "The ontogenetic development of the diencephalic centers in a bird's brain (chick) and comparison with the reptilian and mammalian diencephalon". The Journal of Comparative Neurology 66: 23. doi:10.1002/cne.900660103.

[24] Shimamura, K; Hartigan, DJ; Martinez, S; Puelles, L; Rubenstein, JL (1995). "Longitudinal organization of the anterior neural plate and neural tube". Development 121 (12): 3923–33. PMID 8575293.

[cell-25] Scholpp, Steffen; Lumsden, Andrew (2010). "Building a bridal chamber: Development of the thalamus". Trends in Neurosciences 33 (8): 373–80. doi:10.1016/j.tins.2010.05.003. PMC 2954313. PMID 20541814.

[26] Hirata, T.; Nakazawa, M; Muraoka, O; Nakayama, R; Suda, Y; Hibi, M (2006). "Zinc-finger genes Fez and Fez-like function in the establishment of diencephalon subdivisions". Development 133 (20): 3993–4004. doi:10.1242/dev.02585. PMID 16971467.

[27] Jeong, J.-Y.; Einhorn, Z.; Mathur, P.; Chen, L.; Lee, S.; Kawakami, K.; Guo, S. (2007). "Patterning the zebrafish diencephalon by the conserved zinc-finger protein Fezl". Development 134 (1): 127–36. doi:10.1242/dev.02705. PMID 17164418.

[28] Acampora, D; Avantaggiato, V; Tuorto, F; Simeone, A (1997). "Genetic control of brain morphogenesis through Otx gene dosage requirement". Development 124 (18): 3639–50. PMID 9342056.

[29] Scholpp, S.; Foucher, I.; Staudt, N.; Peukert, D.; Lumsden, A.; Houart, C. (2007). "Otx1l, Otx2 and Irx1b establish and position the ZLI in the diencephalon". Development 134 (17): 3167–76. doi:10.1242/dev.001461. PMID 17670791.

[30] Puelles, L; Rubenstein, JL (2003). "Forebrain gene expression domains and the evolving prosomeric model". Trends in neurosciences 26 (9): 469–76. doi:10.1016/S0166-2236(03)00234-0. PMID 12948657.

[31] Ishibashi, M; McMahon, AP (2002). "A sonic hedgehog-dependent signaling relay regulates growth of diencephalic and mesencephalic primordia in the early mouse embryo". Development 129 (20): 4807–19. PMID 12361972.

[32] Kiecker, C; Lumsden, A (2004). "Hedgehog signaling from the ZLI regulates diencephalic regional identity". Nature Neuroscience 7 (11): 1242–9. doi:10.1038/nn1338. PMID 15494730.

[33] Scholpp, S.; Wolf, O; Brand, M; Lumsden, A (2006). "Hedgehog signalling from the zona limitans intrathalamica orchestrates patterning of the zebrafish diencephalon". Development 133 (5): 855–64. doi:10.1242/dev.02248. PMID 16452095.

[34] Scholpp, S.; Delogu, A.; Gilthorpe, J.; Peukert, D.; Schindler, S.; Lumsden, A. (2009). "Her6 regulates the neurogenetic gradient and neuronal identity in the thalamus". Proceedings of the National Academy of Sciences 106 (47): 19895–900. doi:10.1073/pnas.0910894106. PMC 2775703. PMID 19903880.

[35] Vue, Tou Yia; Bluske, Krista; Alishahi, Amin; Yang, Lin Lin; Koyano-Nakagawa, Naoko; Novitch, Bennett; Nakagawa, Yasushi (2009). "Sonic Hedgehog Signaling Controls Thalamic Progenitor Identity and Nuclei Specification in Mice". Journal of Neuroscience 29 (14): 4484–97. doi:10.1523/JNEUROSCI.0656-09.2009. PMC 2718849. PMID 19357274.

[36] Young, Keith A.; Holcomb, Leigh A.; Bonkale, Willy L.; Hicks, Paul B.; Yazdani, Umar; German, Dwight C. (2007). "5HTTLPR Polymorphism and Enlargement of the Pulvinar: Unlocking the Backdoor to the Limbic System". Biological Psychiatry 61 (6): 813–8. doi:10.1016/j.biopsych.2006.08.047. PMID 17083920.

[37] Dejerine, J.; Roussy, G. (1906). "Le syndrome thalamique". Revue Neurologique 14: 521–32.

[38] Gray, H. & Carter, H. V. (1858), Anatomy Descriptive and Surgical, London: John W. Parker and Son, Retrieved (16 October 2011) [2012-02-10] → [1]

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thalamic