WordNet
- one behind the other; "ride tandem on a bicycle built for two"; "riding horses down the path in tandem" (同)in tandem
- an arrangement of two or more objects or persons one behind another
- the act of copying or making a duplicate (or duplicates) of something; "this kind of duplication is wasteful" (同)gemination
PrepTutorEJDIC
- 前後一留に; / 縦並びの,前後に座席のある / 縦につないだ2頭の馬;縦列2頭立ての馬車 / 二人乗り自転車
- 〈U〉複製(複写)すること / 〈C〉複製した物
UpToDate Contents
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English Journal
- The antitumor compound triazoloacridinone C-1305 inhibits FLT3 kinase activity and potentiates apoptosis in mutant FLT3-ITD leukemia cells.
- Augustin E1, Skwarska A1, Weryszko A1, Pelikant I1, Sankowska E1, Borowa-Mazgaj B1.
- Acta pharmacologica Sinica.Acta Pharmacol Sin.2015 Feb 2. doi: 10.1038/aps.2014.142. [Epub ahead of print]
- Aim:FMS-like receptor tyrosine kinase (FLT3) is expressed in some normal hematopoietic cell types and plays an important role in the pathogenesis of acute myeloid leukemia (AML). In this study, we examined the effects of triazoloacridinone C-1305, an antitumor compound, on AML cells with different F
- PMID 25640477
- Maintenance lenalidomide in combination with 5-azacitidine as post-remission therapy for acute myeloid leukaemia.
- Wei A1, Tan P, Perruzza S, Govindaraj C, Fleming S, McManus J, Avery S, Patil S, Stevenson W, Plebanski M, Spencer A.
- British journal of haematology.Br J Haematol.2015 Feb 2. doi: 10.1111/bjh.13281. [Epub ahead of print]
- In this Phase 1b study, the safety and tolerability of maintenance therapy, comprising lenalidomide (0-25 mg, days 5-25) in combination with azacitidine (50-75 mg/m2 , days 1-5) every 28 d, was explored in 40 patients with acute myeloid leukaemia (AML) in complete remission after chemotherapy. El
- PMID 25643589
- Tandem Duplication of Exons 1-7 Neither Impairs ATP7A Expression Nor Causes a Menkes Disease Phenotype.
- Choi EY1, Patel K, Haddad MR, Yi L, Holmes C, Goldstein DS, Dutra A, Pak E, Kaler SG.
- JIMD reports.JIMD Rep.2015 Feb 1. [Epub ahead of print]
- ATP7A duplications are estimated to represent the molecular cause of Menkes disease in 4-10% of affected patients. We identified a novel duplication of ATP7A exons 1-7 discovered in the context of a challenging prenatal diagnostic situation. All other reported ATP7A duplications (n = 24) involved in
- PMID 25638460
Japanese Journal
- Mimicking the evolution of a thermally stable monomeric four-helix bundle by fusion of four identical single-helix peptides
- AKANUMA Satoshi,MATSUBA Taku,UENO Emi,UMEDA Naoki,YAMAGISHI Akihiko
- The journal of biochemistry 147(3), 371-379, 2010-03-01
- NAID 10027874484
- Origin and Genetic Evolution of the Vertebrate Skeleton
- Wada Hiroshi
- Zoological science 27(2), 119-123, 2010-02
- … In contrast, the cassette for bone recruited new genetic material produced by tandem duplication of the SPARC/osteonectin genes. … Comparative genome analysis revealed similar molecular evolutionary histories for the genetic cassettes for cartilage and bone, namely duplication of the ancestral genetic cassette and recruitment of novel genetic material. …
- NAID 40017358562
- Complete mitochondrial genomes and novel gene rearrangements in two dicroglossid frogs, Hoplobatrachus tigerinus and Euphlyctis hexadactylus, from Bangladesh
- Alam Mohammad Shafiqul,Kurabayashi Atsushi,Hayashi Yoko,Sano Naomi,Khan Md. Mukhlesur Rahman,Fujii Tamotsu,Sumida Masayuki
- Genes & Genetic Systems 85(3), 219-232, 2010
- … hexadactylus can be explained by the tandem duplication and random loss model, except translocation of tRNA-Pro in E. …
- NAID 130000413750
Related Links
- Model for the involvement of strand slippage during DNA replication in the tandem duplication process. The tandem duplication mechanism may be a two-step process. A,the presence of the R6K γ origin of replication in the vicinity ...
- tandem duplication [′tan·dəm ‚dü·plə′kā·shən] (cell and molecular biology) The occurrence of two identical sequences, one following the other, in a ... About EPZ-5676 Epizyme is developing EPZ-5676, a small molecule inhibitor of ...
Related Pictures
★リンクテーブル★
[★]
- 英
- tandem duplication
- 関
- 縦列重複
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- 英
- tandem duplication
- 関
- 直列重複
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遺伝子内縦列重複
- 関
- ITD
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- 関
- tandemly