硫酸アデニルトランスフェラーゼ、硫酸アデニリルトランスフェラーゼ
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/06/02 21:39:46」(JST)
| sulfate adenylyltransferase (ATP) | |||||||||
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| Identifiers | |||||||||
| EC number | 2.7.7.4 | ||||||||
| CAS number | 9012-39-9 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / EGO | ||||||||
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| ATP-sulfurylase | |||||||||
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crystal structure of atp sulfurylase from thermus thermophillus hb8 in complex with aps
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| Identifiers | |||||||||
| Symbol | ATP-sulfurylase | ||||||||
| Pfam | PF01747 | ||||||||
| InterPro | IPR002650 | ||||||||
| SCOP | 1i2d | ||||||||
| SUPERFAMILY | 1i2d | ||||||||
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In enzymology, a sulfate adenylyltransferase (EC 2.7.7.4) is an enzyme that catalyzes the chemical reaction
Thus, the two substrates of this enzyme are ATP and sulfate, whereas its two products are diphosphate and adenylyl sulfate.
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). The systematic name of this enzyme class is ATP:sulfate adenylyltransferase. Other names in common use include adenosine-5'-triphosphate sulfurylase, adenosinetriphosphate sulfurylase, adenylylsulfate pyrophosphorylase, ATP sulfurylase, ATP-sulfurylase, and sulfurylase. This enzyme participates in 3 metabolic pathways: purine metabolism, selenoamino acid metabolism, and sulfur metabolism.
Some sulfate adenylyltransferases are part of a bifunctional polypeptide chain associated with adenosyl phosphosulfate (APS) kinase. Both enzymes are required for PAPS (phosphoadenosine-phosphosulfate) synthesis from inorganic sulfate.[1][2]
As of late 2007, 18 structures have been solved for this class of enzymes, with PDB accession codes 1G8F, 1G8G, 1G8H, 1I2D, 1J70, 1JEC, 1JED, 1JEE, 1JHD, 1M8P, 1R6X, 1TV6, 1V47, 1X6V, 1XJQ, 1XNJ, 1ZUN, and 2GKS.
ATP sulfurylase is one of the enzymes used in pyrosequencing.
This enzyme-related article is a stub. You can help Wikipedia by expanding it.
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This article incorporates text from the public domain Pfam and InterPro IPR002650
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| リンク元 | 「硫酸アデニルトランスフェラーゼ」「硫酸アデニリルトランスフェラーゼ」「sulfurylase」「ATP sulfurylase」 |
| 関連記事 | 「sulfate」「adenylyltransferase」「sulfated」「sulfa」 |