suipoxvirus

English Journal

A novel vaccine against Porcine circovirus type 2 (PCV2) and Streptococcus equi ssp. zooepidemicus (SEZ) co-infection.

Lin HX1, Ma Z1, Yang XQ1, Fan HJ2, Lu CP1.
Veterinary microbiology.Vet Microbiol.2014 Jun 25;171(1-2):198-205. doi: 10.1016/j.vetmic.2014.03.018. Epub 2014 Mar 25.
To develop a vaccine against Porcine circovirus type 2 (PCV2) and Streptococcus equi ssp. zooepidemicus (SEZ) co-infection, the genes of porcine IL-18, capsid protein (Cap) of PCV2 and M-like protein (SzP) of SEZ were inserted into the swinepox virus (SPV) genome by homologous recombination. The rec
PMID 24726504

Protection of guinea pigs by vaccination with a recombinant swinepox virus co-expressing HA1 genes of swine H1N1 and H3N2 influenza viruses.

Xu J1, Yang D, Huang D, Xu J, Liu S, Lin H, Zhu H, Liu B, Lu C.
Archives of virology.Arch Virol.2013 Mar;158(3):629-37. doi: 10.1007/s00705-012-1539-9. Epub 2012 Nov 8.
Swine influenza (SI) is an acute respiratory infectious disease of swine caused by swine influenza virus (SIV). SIV is not only an important respiratory pathogen in pigs but also a potent threat to human health. Here, we report the construction of a recombinant swinepox virus (rSPV/H3-2A-H1) co-expr
PMID 23135159

Immune responses and protective efficacy of a recombinant swinepox virus co-expressing HA1 genes of H3N2 and H1N1 swine influenza virus in mice and pigs.

Xu J1, Huang D, Xu J, Liu S, Lin H, Zhu H, Liu B, Chen W, Lu C.
Veterinary microbiology.Vet Microbiol.2013 Feb 22;162(1):259-64. doi: 10.1016/j.vetmic.2012.11.026. Epub 2012 Nov 29.
The recombinant swine poxvirus rSPV/H3-2A-H1 co-expressing HA1 genes of H3N2 and H1N1 subtype SIV has been constructed and identified. Inoculations of rSPV/H3-2A-H1 yielded ELISA and neutralization antibodies against SIV H1N1 and H3N2, and elicited potent H1N1 and H3N2 SIV-specific INF-γ response f
PMID 23265244