- 亜ミトコンドリアの
English Journal
- Role of mitochondria in the leishmanicidal effects and toxicity of acyl phloroglucinol derivatives: nemorosone and guttiferone A.
- Monzote L1, Lackova A2, Staniek K2, Cuesta-Rubio O3, Gille L2.
- Parasitology.Parasitology.2015 Jun 1:1-10. [Epub ahead of print]
- Nemorosone (Nem) and guttiferone A (GutA) are acyl phloroglucinol derivatives (APD) that are present in different natural products. For both compounds anti-cancer and anti-microbial properties have been reported. In particular, an anti-leishmanial activity of both compounds was demonstrated. The aim
- PMID 26027642
- Amilorides bind to the quinone binding pocket of bovine mitochondrial complex I.
- Murai M1, Murakami S1, Ito T1, Miyoshi H1.
- Biochemistry.Biochemistry.2015 May 5;54(17):2739-46. doi: 10.1021/acs.biochem.5b00187. Epub 2015 Apr 16.
- Amilorides, well-known inhibitors of Na(+)/H(+) antiporters, were previously shown to inhibit bacterial and mitochondrial NADH-quinone oxidoreductase (complex I) but were markedly less active for complex I. Because membrane subunits ND2, ND4, and ND5 of bovine complex I are homologous to Na(+)/H(+)
- PMID 25849763
- Selective inhibition of deactivated mitochondrial complex I by biguanides.
- Matsuzaki S1, Humphries KM1.
- Biochemistry.Biochemistry.2015 Mar 24;54(11):2011-21. doi: 10.1021/bi501473h. Epub 2015 Mar 9.
- Biguanides are widely used antihyperglycemic agents for diabetes mellitus and prediabetes treatment. Complex I is the rate-limiting step of the mitochondrial electron transport chain (ETC), a major source of mitochondrial free radical production, and a known target of biguanides. Complex I has two r
- PMID 25719498
Japanese Journal
- Changes in Small Heat Shock Proteins HSPB1, HSPB5 and HSPB8 in Mitochondria of the Failing Heart Following Myocardial Infarction in Rats
- Biological and Pharmaceutical Bulletin 36(4), 529-539, 2013
- NAID 130003361384
- 農作物防腐剤オルトフェニルフェノール(OPP)のミトコンドリア毒性
- 鹿児島純心女子大学看護栄養学部紀要 16, 46-52, 2012
- NAID 120005566889
- Protective Effect of Salvianic Acid A on Acute Liver Injury Induced by Carbon Tetrachloride in Rats(Pharmacology)
- Biological & pharmaceutical bulletin 30(1), 44-47, 2007-01-01
- NAID 110006153264
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- A submitochondrial particle is a compartmentalized membranous product of exposing mitochondria to ultrasound. This causes the cristae to pinch off forcing the inner mitochondrial membrane inside out. As a consequence, the F1 particle ...
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