English Journal

Neural stem cell- and neurogenesis-related gene expression profiles in the young and aged dentate gyrus.

Shetty GA, Hattiangady B, Shetty AK.SourceInstitute for Regenerative Medicine, Texas A&M Health Science Center College of Medicine at Scott & White, 5701 Airport Road, Module C, Temple, 76502, TX, USA.
Age (Dordrecht, Netherlands).Age (Dordr).2013 Dec;35(6):2165-76. doi: 10.1007/s11357-012-9507-6. Epub 2013 Jan 16.
Hippocampal neurogenesis, important for memory and mood function, wanes greatly in old age. Studies in rat models have implied that this decrease is not due to loss of neural stem cells (NSCs) in the subgranular zone of the dentate gyrus (DG) but rather due to an increased quiescence of NSCs. Additi
PMID 23322452

A single administration of human umbilical cord blood T cells produces long-lasting effects in the aging hippocampus.

Shahaduzzaman M, Golden JE, Green S, Gronda AE, Adrien E, Ahmed A, Sanberg PR, Bickford PC, Gemma C, Willing AE.SourceCenter for Excellence in Aging and Brain Repair, Department of Neurosurgery and Brain Repair, Morsani College of Medicine, University of South Florida, 12901 Bruce B. Downs Blvd, MDC78, Tampa, FL, 33612, USA, mshahad@health.usf.edu.
Age (Dordrecht, Netherlands).Age (Dordr).2013 Dec;35(6):2071-87. doi: 10.1007/s11357-012-9496-5. Epub 2012 Dec 22.
Neurogenesis occurs throughout life but significantly decreases with age. Human umbilical cord blood mononuclear cells (HUCB MNCs) have been shown to increase the proliferation of neural stem cells (NSCs) in the dentate gyrus (DG) of the hippocampus and the subgranular zone of aging rats (Bachstette
PMID 23263793

ZY-1, A Novel Nicotinic Analog, Promotes Proliferation and Migration of Adult Hippocampal Neural Stem/Progenitor Cells.

He N, Wang Z, Wang Y, Shen H, Yin M.SourceSchool of Pharmacy, Shanghai Jiao Tong University, Shanghai, 200240, China.
Cellular and molecular neurobiology.Cell Mol Neurobiol.2013 Nov;33(8):1149-57. doi: 10.1007/s10571-013-9981-0. Epub 2013 Sep 22.
Neural stem/progenitor cells (NSPCs) of the subgranular zone have been implicated in cognitive processes, which represent a potentially important source of regenerative medicine for the treatment of neurodegenerative diseases such as Alzheimer's disease (AD). In our previous studies, ZY-1, a novel n
PMID 24057433

Japanese Journal

Hippocampal Neurogenesis as a Critical Target of Neurotoxicants Contained in Foods

Food Safety 3(1), 1-15, 2015
… Monitoring of granule cell lineage in the subgranular zone (SGZ) and γ-aminobutyric acid (GABA)-ergic interneurons in the dentate hilus is effective for detection of target cell populations of DNT as manifested by disruption of neurogenesis. …
NAID 130005064504

Hippocampal Neurogenesis as a Critical Target of Neurotoxicants Contained in Foods

Food Safety advpub(0), 2015
… Monitoring of granule cell lineage in the subgranular zone (SGZ) and γ-aminobutyric acid (GABA)-ergic interneurons in the dentate hilus is effective for detection of target cell populations of DNT as manifested by disruption of neurogenesis. …
NAID 130005003371

Effects of Bupropion and Pramipexole on Cell Proliferation in the Hippocampus of Adrenocorticotropic Hormone-Treated Rats

, , , , ,
Biological and Pharmaceutical Bulletin 37(2), 327-330, 2014
… In this study, we used the mitotic marker 5-bromo-2′-deoxyridine to investigate the effects of bupropion and pramipexole on cell proliferation in the subgranular zone of the hippocampal dentate gyrus following chronic treatment with ACTH. …
NAID 130003390932