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1. リポ蛋白および止血因子に対する運動の影響 effects of exercise on lipoproteins and hemostatic factors
2. 血液疾患における免疫グロブリンの静脈内投与 intravenous immune globulin in hematologic disorders
3. 閉経期のホルモン療法と心血管リスク menopausal hormone therapy and cardiovascular risk
4. HDL代謝およびHDLコレステロール値異常の患者に対するアプローチ hdl metabolism and approach to the patient with abnormal hdl cholesterol levels
5. 尿毒症毒素 uremic toxins

English Journal

In vitro inhibitory effect on pancreatic lipase activity of subfractions from ethanol extracts of fermented oats (Avena sativa L.) and synergistic effect of three phenolic acids.

Cai S, Wang O, Wang M, He J, Wang Y, Zhang D, Zhou F, Ji B.AbstractThe purpose of the present work is to study the pancreatic lipase inhibitory effects of different subfractions (n-hexane, ethyl acetate (EA), n-butanol, and water subfraction) from ethanol extracts of non-fermented and fungi-fermented oats, and to delineate the interactions of three primary phenolic acids in the EA subfractions. The EA subfraction showed the highest inhibitory effect on pancreatic lipase activity at 1.5 mg/mL compared to the other subfractions, regardless of fermentation or not. Meanwhile, both of the EA subfractions of two fungi-fermented oats demonstrated more effective inhibitory activity than that of non-fermented oats. A positive correlation between the total phenolics content and inhibitory activity was found. The inhibitory ability of the EA subfraction from non-fermented or fermented oats also displayed a dose-dependent effect. The standards of caffeic, ferulic, and p-coumaric acids, mainly included in EA subfractions of fermented oats, also displayed a dose-dependent inhibitory effect. A synergistic effect of each binary combination of p-coumaric, ferulic, and caffeic acid was observed, especially at 150.0 μg/mL. Those results indicate that fungi-fermented oats have a more effective inhibitory ability on pancreatic lipase, polyphenols may be the most effective component, and could be potentially used for dietary therapy of obesity.
Journal of agricultural and food chemistry.J Agric Food Chem.2012 Jul 5. [Epub ahead of print]
The purpose of the present work is to study the pancreatic lipase inhibitory effects of different subfractions (n-hexane, ethyl acetate (EA), n-butanol, and water subfraction) from ethanol extracts of non-fermented and fungi-fermented oats, and to delineate the interactions of three primary phenolic
PMID 22765648

Gingko biloba Extract Inhibits Oxidative Stress and Ameliorates Impaired Glial Fibrillary Acidic Protein Expression, but Can Not Improve Spatial Learning in Offspring from Hyperhomocysteinemic Rat Dams.

Koz ST, Baydas G, Koz S, Demir N, Nedzvetsky VS.SourceMalatya State Hospital, Physiology Laboratory, 44000, Malatya, Turkey. kozsema@hotmail.com.
Phytotherapy research : PTR.Phytother Res.2012 Jul;26(7):949-55. doi: 10.1002/ptr.3669. Epub 2011 Nov 10.
We aimed to study the effects of gingko biloba extract (EGb) on oxidative stress, astrocyte maturation and cognitive disfunction in offspring of hyperhomocysteinemic rats. Hyperhomocysteinemia was induced in the pregnant rats by administration of methionine (1 gr/kg body weight) dissolved in drink
PMID 22076950

Japanese Journal

Reactivity of Direct Assays for Low-Density Lipoprotein (LDL) Cholesterol Toward Charge-Modified LDL in Hypercholesterolemia

ZHANG Bo,KAWACHI Emi,MATSUNAGA Akira,IMAIZUMI Satoshi,NODA Keita,UEHARA Yoshinari,MIURA Shin-ichiro,YOSHINAGA Kazuhiko,KUROKI Masahide,SAKU Keijiro
Circulation journal : official journal of the Japanese Circulation Society 76(9), 2241-2248, 2012-08-25
Background: The aim of the present study was to compare 2 direct measurements for low-density lipoprotein cholesterol (LDL-C) with the Friedewald calculation (LDL-C [F]) in serum and their relationshi …
NAID 10030697012

Negatively charged low-density lipoprotein is associated with atherogenic risk in hypertensive patients

Urata Jungo,Ikeda Satoshi,Koga Seiji,Nakata Tomoo,Yasunaga Tomohiko,Sonoda Koichiro,Koide Yuji,Ashizawa Naoto,Kohno Shigeru,Maemura Koji
Heart and Vessels 27(3), 235-242, 2012-05
… These data suggest that LDL subfractions are associated with multiple atherogenic risk factors and that treatment to modify these risk factors could result in changes in LDL subfraction levels. …
NAID 120004702413