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relating to or existing on or affecting the skin; "cutaneous nerves"; "a cutaneous infection" (同)cutaneal, dermal
any of several forms of ulcerative skin disease
less than acute; relating to a disease present in a person with no symptoms of it
a constellation in the southern hemisphere near Centaurus

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皮膚の,皮膚を冒す
狼瘡(ろうそう)(皮膚結核の一種)

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/02/05 12:31:14」(JST)

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Subacute cutaneous lupus erythematosus (SCLE) is a clinically distinct subset of cases of lupus erythematosus that is most often present in white women aged 15 to 40, consisting of skin lesions that are scaly and evolve as polycyclic annular lesions or psoriasiform plaques.^[1]

Characteristically the lesions appear in sun-exposed areas such as the vee of the neckline or the forearms, but not the face. It may be brought on by sun-sensitizing medications, but is usually associated with autoimmune disorders such as rheumatoid arthritis and Sjögren's syndrome.^[2]

Treatment generally involves sun avoidance/protection and topical corticosteroids.^[2] Sometimes systemic drug treatment is necessary. Besides corticosteroids other immunosuppressants such as methotrexate are also used.^[3]

Lesions of SCLE may have an annular configuration, with raised red borders and central clearing.^[4]^[5]

References

^ James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. Page 160. ISBN 0-7216-2921-0.
^ ^a ^b Burkhalter NW, McKenzie JT, Lane JE (2009). "Subacute cutaneous lupus erythematosus". Consultant 49 (3).
^ Boehm IB, Boehm GA, Bauer R (1998). "Management of cutaneous lupus erythematosus with low-dose methotrexate: indication for modulation of inflammatory mechanisms". Rheumatology International 18 (2): 59–62. doi:10.1007/s002960050058. PMID 9782534.
^ Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. p. 563. ISBN 1-4160-2999-0.
^ Sontheimer RD, Thomas JR, Gilliam JN (December 1979). "Subacute cutaneous lupus erythematosus: a cutaneous marker for a distinct lupus erythematosus subset". Arch Dermatol 115 (12): 1409–15. doi:10.1001/archderm.1979.04010120007006. PMID 533284.

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1. 皮膚エリテマトーデスの概要overview of cutaneous lupus erythematosus [show details]
…Generalized ACLE; Toxic epidermal necrolysis-like ACLE; Subacute cutaneous lupus erythematosus (SCLE) Annular SCLE; Papulosquamous SCLE ; Drug-induced SCLE; Less common variants: erythrodermic, poikilodermatous …
2. 円板状ループスおよび亜急性皮膚ループスの初期マネージメントinitial management of discoid lupus and subacute cutaneous lupus [show details]
… Discoid lupus erythematosus (DLE) and subacute cutaneous lupus erythematosus (SCLE) are variants of cutaneous lupus that may occur independently or as manifestations of systemic lupus erythematosus. DLE …
3. 難治性円板状ループスおよび亜急性皮膚ループスのマネージメントmanagement of refractory discoid lupus and subacute cutaneous lupus [show details]
… Discoid lupus erythematosus (DLE) and subacute cutaneous lupus erythematosus (SCLE) are variants of cutaneous lupus erythematosus (LE) that may occur independently or as manifestations of systemic lupus …
4. 光線過敏症（光線皮膚症）：臨床症状、診断、および治療photosensitivity disorders photodermatoses clinical manifestations diagnosis and treatment [show details]
…presented separately. Drug-induced subacute cutaneous lupus erythematosus (SCLE) presents with a photosensitive cutaneous eruption identical to idiopathic SCLE . Among the medications reported to induce …
5. 薬物誘発性ループスdrug induced lupus [show details]
…systemic lupus erythematosus (SLE), although subacute cutaneous lupus erythematosus (SCLE) is often drug-induced. Subacute cutaneous lupus erythematosus (SCLE) may be drug-induced in a substantial proportion …

English Journal

Dermoscopy of subacute cutaneous lupus erythematosus.

Errichetti E1, Piccirillo A2, Viola L2, Stinco G3.
International journal of dermatology.Int J Dermatol.2016 Nov;55(11):e605-e607. doi: 10.1111/ijd.13331.
PMID 27260752

JAK3 as an Emerging Target for Topical Treatment of Inflammatory Skin Diseases.

Alves de Medeiros AK1,2, Speeckaert R1,2, Desmet E2, Van Gele M2, De Schepper S1, Lambert J1,2.
PloS one.PLoS One.2016 Oct 6;11(10):e0164080. doi: 10.1371/journal.pone.0164080. eCollection 2016.
The recent interest and elucidation of the JAK/STAT signaling pathway created new targets for the treatment of inflammatory skin diseases (ISDs). JAK inhibitors in oral and topical formulations have shown beneficial results in psoriasis and alopecia areata. Patients suffering from other ISDs might a
PMID 27711196

Chronic Pruritus and Connective Tissue Disorders: Review, Gaps, and Future Directions.

Haber JS1, Valdes-Rodriguez R1, Yosipovitch G2.
American journal of clinical dermatology.Am J Clin Dermatol.2016 Oct;17(5):445-449.
Chronic itch is a common skin manifestation in many connective tissue diseases. However, the cause of chronic itch in these diseases is still not fully understood. The complex, and in some cases incomplete understanding of, pathogenesis in each condition makes it difficult to target specific mediato
PMID 27260190

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