亜急性細菌性心内膜炎 SBE,
WordNet
- (microbiology) single-celled or noncellular spherical or spiral or rod-shaped organisms lacking chlorophyll that reproduce by fission; important as pathogens and for biochemical properties; taxonomy is difficult; often considered to be plants (同)bacterium
- relating to or caused by bacteria; "bacterial infection"
- less than acute; relating to a disease present in a person with no symptoms of it
- inflammation of the endocardium and heart valves
PrepTutorEJDIC
- 『バクテリア』,細菌
- バクテリアの,細菌の
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2012/12/17 00:39:22」(JST)
[Wiki en表示]
Subacute bacterial endocarditis |
Classification and external resources |
ICD-10 |
I33.0 |
ICD-9 |
421.0 |
MeSH |
D004698 |
Subacute bacterial endocarditis (also called endocarditis lenta) is a type of endocarditis (more specifically, infective endocarditis).
It can be confused with essential mixed cryoglobulinemia.[1]
It can be considered a form of Type III hypersensitivity.[2]
Contents
- 1 Diagnosis
- 2 Causes
- 3 Prognosis
- 4 Treatment
- 5 References
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Diagnosis
Osler's nodes can indicate this condition.[3] Nail clubbing is also often seen in subacute endocarditis.
Causes
It is usually caused by a form of streptococci viridans bacteria that normally live in the mouth and throat (Streptococcus mutans, mitis, sanguis or milleri). Other strains of streptococci (bovis and equines) can also cause subacute endocarditis, usually in patients who have a form of gastrointestinal cancer.
Prognosis
Underlying structural valve disease is usually present in patients before developing subacute endocarditis. It is less likely to lead to septic emboli than is acute endocarditis, but subacute endocarditis has a relatively slow process of infection and, if left untreated, can worsen for up to one year before it is fatal.
Summary
In cases of subacute bacterial endocarditis, the causative organism (streptococcus viridans) needs a previous heart valve disease to colonize and cause such disease.
On the other hand, in cases of acute bacterial endocarditis, the organism can colonize on the healthy heart valve, causing the disease.
Treatment
The standard treatment is with a minimum of four weeks of high-dose intravenous penicillin with an aminoglycoside such as gentamicin. The use of high-dose antibiotics is largely based upon animal models.[4] Leo Loewe of Brooklyn Jewish Hospital was the first to successfully treat subacute bacterial endocarditis with penicillin. Loewe reported seven cases in 1944.[5]
References
- ^ Agarwal A, Clements J, Sedmak DD, et al. (December 1997). "Subacute bacterial endocarditis masquerading as type III essential mixed cryoglobulinemia". J. Am. Soc. Nephrol. 8 (12): 1971–6. PMID 9402102. http://jasn.asnjournals.org/cgi/pmidlookup?view=long&pmid=9402102.
- ^ "Definition: immune complex disease from Online Medical Dictionary". http://128.240.24.212/cgi-bin/omd?type+III+hypersensitivity+reaction.
- ^ "Osler nodes" at Dorland's Medical Dictionary
- ^ Verhagen DW, Vedder AC, Speelman P, van der Meer JT (2006). "Antimicrobial treatment of infective endocarditis caused by viridans streptococci highly susceptible to penicillin: historic overview and future considerations". J. Antimicrob. Chemother. 57 (5): 819–24. doi:10.1093/jac/dkl087. PMID 16549513. http://jac.oxfordjournals.org/cgi/pmidlookup?view=long&pmid=16549513.
- ^ LEO LOEWE, M.D.; PHILIP ROSENBLATT, M.D.; HARRY J. GREENE, M.D.; MORTIMER RUSSELL. COMBINED PENICILLIN AND HEPARIN THERAPY OF SUBACUTE BACTERIAL ENDOCARDITIS. JAMA 1944;124(3):144-149
Cardiovascular disease: heart disease · Circulatory system pathology (I00–I52, 390–429)
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Ischaemic |
CD/CHD
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CAD · Coronary thrombosis · Coronary vasospasm · Coronary artery aneurysm · Coronary artery dissection · Myocardial Bridge
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Active ischemia
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Angina pectoris (Prinzmetal's angina, Stable angina) · Acute coronary (Unstable angina, Myocardial infarction / heart attack)
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Sequelae
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hours (Myocardial stunning, Hibernating myocardium) · days (Myocardial rupture) · weeks (Aneurysm of heart/Ventricular aneurysm, Dressler's syndrome)
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Layers |
Pericardium
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Pericarditis (Acute, Chronic/Constrictive) · Pericardial effusion (Hemopericardium, Cardiac tamponade)
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Myocardium
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Myocarditis (Chagas disease)
Cardiomyopathy: Dilated (Alcoholic) · Hypertrophic · Restrictive (Loeffler endocarditis, Cardiac amyloidosis, Endocardial fibroelastosis)
Arrhythmogenic right ventricular dysplasia
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Endocardium/
valves
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Endocarditis
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Infective endocarditis (Subacute bacterial endocarditis) · noninfective endocarditis (Nonbacterial thrombotic endocarditis, Libman-Sacks endocarditis)
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Valves
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mitral (regurgitation, prolapse, stenosis) · aortic (stenosis, insufficiency) · tricuspid (stenosis, insufficiency) · pulmonary (stenosis, insufficiency)
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Conduction/
arrhythmia |
Bradycardia
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Sinus bradycardia · Sick sinus syndrome
Heart block: Sinoatrial · AV (1°, 2°, 3°) · Intraventricular (Bundle branch/Right/Left, Left anterior fascicular/Left posterior fascicular, Bifascicular/Trifascicular) · Adams–Stokes syndrome
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Tachycardia
(paroxysmal and sinus)
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Supraventricular
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Atrial (Multifocal) · Junctional (AV nodal reentrant, Junctional ectopic)
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Ventricular
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Torsades de pointes · Catecholaminergic polymorphic · Accelerated idioventricular rhythm
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Premature contraction
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Atrial · Ventricular
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Pre-excitation syndrome
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Wolff-Parkinson-White · Lown-Ganong-Levine
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Flutter/fibrillation
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Atrial flutter · Ventricular flutter · Atrial fibrillation (Familial) · Ventricular fibrillation
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Pacemaker
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Wandering pacemaker · Ectopic pacemaker/Ectopic beat · Parasystole · Multifocal atrial tachycardia · Pacemaker syndrome
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Long QT syndrome
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Romano-Ward syndrome · Andersen-Tawil syndrome · Jervell and Lange-Nielsen syndrome
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Cardiac arrest
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Sudden cardiac death · Asystole · Pulseless electrical activity · Sinoatrial arrest
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Other/ungrouped
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hexaxial reference system (Right axis deviation, Left axis deviation) · QT (Short QT syndrome) · T (T wave alternans) · ST (Osborn wave, ST elevation, ST depression)
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Cardiomegaly |
Ventricular hypertrophy (Left, Right/Cor pulmonale) · Atrial enlargement (Left, Right)
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Other |
Cardiac fibrosis · Heart failure (Diastolic heart failure, Cardiac asthma) · Rheumatic fever
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noco/cong/tumr, sysi/epon, injr
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proc, drug (C1A/1B/1C/1D), blte
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Immune disorders: hypersensitivity and autoimmune diseases (279.5–6)
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Type I/allergy/atopy
(IgE) |
Foreign
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Atopic dermatitis · Allergic urticaria · Hay fever · Allergic asthma · Anaphylaxis · Food allergy (Milk, Egg, Peanut, Tree nut, Seafood, Soy, Wheat), Penicillin allergy
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Autoimmune
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none
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Type II/ADCC
(IgM, IgG) |
Foreign
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Pernicious anemia · Hemolytic disease of the newborn
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Autoimmune
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Cytotoxic
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Autoimmune hemolytic anemia · Idiopathic thrombocytopenic purpura · Bullous pemphigoid · Pemphigus vulgaris · Rheumatic fever · Goodpasture's syndrome
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"Type 5"/receptor
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Graves' disease · Myasthenia gravis
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Type III
(Immune complex) |
Foreign
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Henoch–Schönlein purpura · Hypersensitivity vasculitis · Reactive arthritis · Farmer's lung · Post-streptococcal glomerulonephritis · Serum sickness · Arthus reaction
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Autoimmune
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Systemic lupus erythematosus · Subacute bacterial endocarditis · Rheumatoid arthritis
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Type IV/cell-mediated
(T-cells) |
Foreign
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Allergic contact dermatitis · Mantoux test
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Autoimmune
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Diabetes mellitus type 1 · Hashimoto's thyroiditis · Guillain–Barré syndrome · Multiple sclerosis · Coeliac disease · Giant-cell arteritis
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GVHD
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Transfusion-associated graft versus host disease
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Unknown/
multiple |
Foreign
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Hypersensitivity pneumonitis (Allergic bronchopulmonary aspergillosis) · Transplant rejection · Latex allergy (I+IV)
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Autoimmune
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Sjögren's syndrome · Autoimmune hepatitis · Autoimmune polyendocrine syndrome (APS1, APS2) · Autoimmune adrenalitis · Systemic autoimmune disease
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cell/phys/auag/auab/comp, igrc
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UpToDate Contents
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English Journal
- [Multiple pulmonary emboli complicating infective endocarditis in a child with congenital heart disease.]
- Ajdakar S1, Elbouderkaoui M2, Rada N2, Drais G2, Bouskraoui M2.
- Archives de pediatrie : organe officiel de la Societe francaise de pediatrie.Arch Pediatr.2015 Feb 25. pii: S0929-693X(15)00050-0. doi: 10.1016/j.arcped.2015.01.015. [Epub ahead of print]
- Pulmonary embolism in children is a rare condition, associated with high mortality. Clinical presentation is nonspecific. Pulmonary embolism may present initially similar to bacterial endocarditis of the right heart, septic thrombophlebitis, or osteomyelitis. We report the case of a 6-year-old girl
- PMID 25725970
- Granulicatella adiacens subacute bacterial endocarditis as the underlying cause of type II mixed cryoglobulinaemia.
- Sim BW1, Koo RM1, Hawkins C2, Bowden F3, Watson A3.
- BMJ case reports.BMJ Case Rep.2015 Jan 7;2015. pii: bcr2014206091. doi: 10.1136/bcr-2014-206091.
- A 57-year-old man with type II mixed cryoglobulinaemia presented to the emergency department with a history of worsening lethargy, malaise and non-drenching night sweats in a relapsing-remitting pattern. He was diagnosed with type II mixed cryoglobulinaemia 7 months ago following episodes of fever
- PMID 25568266
- Subacute endocarditis of an atrial septal closure device in a patient with a patent foramen ovale.
- Krantz SB1, Lawton JS2.
- The Annals of thoracic surgery.Ann Thorac Surg.2014 Nov;98(5):1821-3. doi: 10.1016/j.athoracsur.2013.12.079. Epub 2014 Oct 30.
- The role of transcatheter closure of a patent foramen ovale for cryptogenic stroke remains controversial. The most common complications include atrial arrhythmia and bleeding. Infectious complications are exceedingly rare. We describe a 37-year-old man with a history of transient ischemic attacks an
- PMID 25441794
Japanese Journal
- Rapidly Progressive Glomerulonephritis Associated with PR3-ANCA Positive Subacute Bacterial Endocarditis
- Fukasawa Hirotaka,Hayashi Maho,Kinoshita Naoko,Ishigaki Sayaka,Isobe Shinsuke,Sakao Yukitoshi,Kato Akihiko,Fujigaki Yoshihide,Furuya Ryuichi
- Internal Medicine 51(18), 2587-2590, 2012
- … Patients with bacterial endocarditis often have renal complications. … This report presents the case of an elderly man with rapidly progressive glomerulonephritis (RPGN) associated with subacute bacterial endocarditis (SBE) due to Enterococcus faecalis infection. …
- NAID 130002062397
- 感染性心内膜炎を合併した顕微鏡的多発血管炎の1剖検例
- 王 克〓,島尻 正平,吉田 敏弥 [他],山田 壮亮,笹栗 靖之
- 産業医科大学雑誌 32(3), 273-279, 2010-09-01
- 症例は87歳の男性.食欲不振と全身倦怠感のため来院となり,血液検査上C-反応性蛋白(CRP)が15.6mg/dlと白血球(WBC)が12500/μlで炎症反応が高値で,CT画像上では気管支肺炎を疑う所見を認めていた.抗生剤ペニシリンを投与したが炎症反応のCRPとWBCの改善を認めず,その後抗好中球細胞質ミエロペルオキシダーゼ抗体(MPO-ANCA)が107U/mlの上昇を認めたため,血管炎が考えら …
- NAID 110007700773
- Sweet's syndrome in a patient with enterococcal subacute bacterial endocarditis
Related Links
- Subacute bacterial endocarditis (also called endocarditis lenta) is a type of endocarditis (more specifically, infective endocarditis). It can be confused with essential mixed cryoglobulinemia. It can be considered a form of Type III hypersensitivity ...
- Definition. Subacute Bacterial Endocarditis (SBE) is a bacterial infection that produces growths on the endocardium (the cells lining the inside of the heart). Subacute bacterial endocarditis usually (but not always) is caused by a viridans ...
Related Pictures
★リンクテーブル★
[★]
- 英
- Roth spot, Roth spots, Roth's spots
- 同
- Roth斑
概念
- ロス斑は白斑を中心と中心とする出血像を示す。ロス斑は綿花状白斑の周りを出血が取り囲んでいる。綿花用白斑は虚血に陥った軸索の膨化(破裂?, bursting)により生じている。毛細血管に入る前の細動脈が虚血により破裂することにより生じている。多くの病態でロス斑が起こるのであって、細菌性心内膜炎に特異的なわけではない。(参考(1))
原因
- 参考3
参考
- http://www.kellogg.umich.edu/theeyeshaveit/optic-fundus/roth-spot.html
- http://www.nejm.org/doi/full/10.1056/NEJMicm040783
- 3. Roland Ling, Bruce James White-centred retinal haemorrhages(Roth spots). Postgrad Med Ja 1998;74:581-582
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2361020/pdf/postmedj00094-0007.pdf
- http://www.uveitis.org/medical/articles/case/Uveitis-%20Roth%20Spots.pdf
- http://www.kellogg.umich.edu/theeyeshaveit/optic-fundus/images/roth-spot.jpg
[★]
- 英
- subacute bacterial endocarditis, SBE
- 関
- 感染性心内膜炎 infective endocarditis
[★]
- 英
- subacute bacterial endocarditis
- 関
- 亜急性細菌性心内膜炎
[★]
[★]
- 関
- bacteria、bacterially、bacterio、bacterium