関: terminal stria

WordNet

relating to or occurring in a term or fixed period of time; "terminal examinations"; "terminal payments"
a contact on an electrical device (such as a battery) at which electric current enters or leaves (同)pole
station where transport vehicles load or unload passengers or goods (同)terminus, depot
electronic equipment consisting of a device providing access to a computer; has a keyboard and display
being or situated at an end; "the endmost pillar"; "terminal buds on a branch"; "a terminal station"; "the terminal syllable"
causing or ending in or approaching death; "a terminal patient"; "terminal cancer"
of or relating to or situated at the ends of a delivery route; "freight pickup is a terminal service"; "terminal charges"
any of a number of tiny parallel grooves such as: the scratches left by a glacier on rocks or the streaks or ridges in muscle tissue (同)striation

PrepTutorEJDIC

『終りの』,末端の / 毎期の,定期の;学期末の / 『死に至る』, / 末端 / (電池の)端子 / (町の中心に近い)空港バス発着場;(一般に,鉄道・バスの)終点,終着駅
(平行に並んでいる)細い溝(筋) / 条線(氷河運動により岩の表面についたかき傷;鉱物の結晶面に走る平行線) / (円柱についている)縦溝

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/01/29 11:42:15」(JST)

wiki en

The stria terminalis (or terminal stria) is a structure in the brain consisting of a band of fibers running along the lateral margin of the ventricular surface of the thalamus. Serving as a major output pathway of the amygdala, the stria terminalis runs from its centromedial division to the ventral medial nucleus of the hypothalamus.

Anatomy

The stria terminalis covers the thalamostriate vein, marking a line of separation between the thalamus and the caudate nucleus as seen upon gross dissection of the ventricles of the brain, viewed from the superior aspect.

The stria terminalis extends from the region of the interventricular foramina to the temporal horn of the lateral ventricle, carrying fibers from the amygdala to the septal nuclei, hypothalamic, and thalamic areas of the brain. It also carries fibers projecting from these areas back to the amygdala.

Functions

The activity of the bed nucleus of the stria terminalis correlates with anxiety in response to threat monitoring.^[1] It is thought to act as a relay site within the hypothalamic-pituitary-adrenal axis and regulate its activity in response to acute stress.^[2] It is also thought to promote behavioral inhibition in response to unfamiliar individuals, by input from the orbitofrontal cortex.^[3] Bilateral disruption of this pathway has been shown to attenuate reinstatement of drug seeking behaviour in rodents.^[4]

Bed nucleus of the stria terminalis (BNST)

The central subdivision of the bed nucleus of the stria terminalis (BSTc) is sexually dimorphic. On average, the BSTc is twice as large in men as in women and contains twice the number of somatostatin neurons.^[5] A sample of six male-to-female transsexuals taking estrogen were found to have female-typical number of cells in the BSTc, whereas a female-to-male transsexual taking testosterone was found to have a male-typical number.^[6]^[7] The authors (W. Chung, G. De Vries, Dick Swaab) also examined subjects with hormone-related disorders and found no pattern between those disorders and the BSTc while the single untreated male-to-female transsexual had a female-typical number of cells. They concluded that the BSTc provides evidence for a neurobiological basis of gender identity disorder and proposed that such was determined before birth.

Criticisms of the former statement suggest^[8] the study used an unrepresentative sample and did not adequately control for hormone replacement therapy, which has been shown to influence hypothalamic size,^[9] even though the study tried to do this by including non-transsexual male and female controls which, for a variety of medical reasons, had experienced hormone reversal.^[6] The statement about the neurobiological basis from birth has later been brought to question, though not refuted, by a follow up study by the same group which found that the sexual dimorphism of the BSTc is not present before adulthood (approximately 22 years of age) even though transsexuals report being aware of their gender identity since childhood.^[10]

Reduction of the size of the bed nucleus of the stria terminalis has been observed in pedophilic male perpetrators, in addition to reductions in the right amygdala, hypothalamus and abnormalities in related structures. The authors propose that childhood deficits in the BNST and medial amygdala may cause inhibition of sexual maturity.^[11]

Additional images

Deep dissection of brain-stem. Lateral view.
Dissection of brain-stem. Dorsal view.
Human brain left dissected midsagittal view

References

^ Somerville L, Whalen P, Kelley W (2010). "Human Bed Nucleus of the Stria Terminalis Indexes Hypervigilant Threat Monitoring". Biol Psychiatry 68 (5): 416–424. doi:10.1016/j.biopsych.2010.04.002. PMC 2921460. PMID 20497902.
^ Choi D, Furay A, Evanson N, Ostrander M, Ulrich-Lai Y, Herman J (2007). "Bed Nucleus of the Stria Terminalis Subregions Differentially Regulate Hypothalamic–Pituitary–Adrenal Axis Activity: Implications for the Integration of Limbic Inputs". J Neurosci 27 (8): 2025–34. doi:10.1523/JNEUROSCI.4301-06.2007. PMID 17314298.
^ Fox A, Shelton S, Oakes T, Converse A, DavidsonR, Kalin N (2010). "Orbitofrontal Cortex Lesions Alter Anxiety-Related Activity in the Primate Bed Nucleus of Stria Terminalis". J Neurosci 30 (20): 7023–27. doi:10.1523/JNEUROSCI.5952-09.2010. PMC 2915894. PMID 20484644.
^ Suzanne Erb · Natalina Salmaso · Demetra Rodaros Jane Stewart (2001). "A role for the CRF-containing pathway from central nucleus of the amygdala to bed nucleus of the stria terminalis in the stress-induced reinstatement of cocaine seeking in rats". Psychopharmacology 158 (4): 360–65. doi:10.1007/s002130000642.
^ Swaab D (2007). "Sexual differentiation of the brain and behavior". Best Pract Res Clin Endocrinol Metab 21 (3): 431–44. doi:10.1016/j.beem.2007.04.003. PMID 17875490.
^ ^a ^b Zhou J, Hofman M, Gooren L, Swaab D (1995). "A sex difference in the human brain and its relation to transsexuality". Nature 378 (6552): 68–70. doi:10.1038/378068a0. PMID 7477289.
^ Kruijver F, Zhou J, Pool C, Hofman M, Gooren L, Swaab D (2000). "Male-to-female transsexuals have female neuron numbers in a limbic nucleus". J. Clin. Endocrinol. Metab. 85 (5): 2034–41. doi:10.1210/jc.85.5.2034. PMID 10843193.
^ Lawrence, A. A. (2007). A critique of the brain-sex theory of transsexualism.
^ Hulshoff Pol, H. E., Cohen-Kettenis, P. T., Van Haren, N. E., Peper, J. S., Brans, R. G., Cahn, W., et al. (2006). Changing your sex changes your brain: Influences of testosterone and estrogen on adult human brain structure. European Journal of Endocrinology, 155(Suppl. 1), S107-S114.
^ Chung W, De Vries G, Swaab D (2002). "Sexual differentiation of the bed nucleus of the stria terminalis in humans may extend into adulthood". J Neurosci 22 (3): 1027–33. PMID 11826131.
^ Schiltz, K., Witzel, J., Northoff, G., Zierhut, K., Gubka, U., Fellman, H., Kaufmann, J., Tempelmann, C., Wiebking, C., & Bogerts, B. (2007). Brain pathology in pedophilic offenders: Evidence of volume reduction in the right amygdala and related diencephalic structures. Archives of General Psychiatry, 64, 737–746.

External links

Photo at University of Pennsylvania
Overview at Everything2
Stained brain slice images which include the "stria terminalis" at the BrainMaps project

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

1. 性転換：疫学、病態生理、および診断 transsexualism epidemiology pathophysiology and diagnosis
2. 心房粗動：洞調律維持 atrial flutter maintenance of sinus rhythm
3. 正常洞調律および洞性不整脈 normal sinus rhythm and sinus arrhythmia
4. 限局性心房性頻拍 focal atrial tachycardia
5. 老人性難聴 presbycusis

English Journal

Differential effects of cocaine on extracellular signal-regulated kinase phosphorylation in nuclei of the extended amygdala and prefrontal cortex of psychogenetically selected roman high- and low-avoidance rats.

Giorgi O1, Corda MG, Sabariego M, Giugliano V, Piludu MA, Rosas M, Acquas E.
Journal of neuroscience research.J Neurosci Res.2015 May;93(5):714-21. doi: 10.1002/jnr.23526. Epub 2014 Dec 11.
Roman high (RHA)- and low (RLA)-avoidance rats are selectively bred for rapid vs. poor acquisition of active avoidance, respectively, and differ markedly in emotional reactivity, coping style, and behavioral and neurochemical responses to morphine and psychostimulants. Accordingly, acute cocaine ind
PMID 25502299

Microstructural White Matter Abnormalities and Cognitive Dysfunction in Subcortical Ischemic Vascular Disease: an Atlas-Based Diffusion Tensor Analysis Study.

Lin L1, Xue Y, Duan Q, Sun B, Lin H, Chen X, Luo L, Wei X, Zhang Z.
Journal of molecular neuroscience : MN.J Mol Neurosci.2015 Apr 10. [Epub ahead of print]
Recent studies in subcortical ischemic vascular disease (SIVD) suggest the involvement of white matter (WM) abnormalities underlying the pathogenesis of cognitive function impairment. Here, we performed magnetic resonance diffusion tensor imaging (DTI) on detecting WM damage and to investigate the c
PMID 25859933

Extending the amygdala in theories of threat processing.

Fox AS1, Oler JA2, Tromp DP2, Fudge JL3, Kalin NH4.
Trends in neurosciences.Trends Neurosci.2015 Apr 4. pii: S0166-2236(15)00061-2. doi: 10.1016/j.tins.2015.03.002. [Epub ahead of print]
The central extended amygdala is an evolutionarily conserved set of interconnected brain regions that play an important role in threat processing to promote survival. Two core components of the central extended amygdala, the central nucleus of the amygdala (Ce) and the lateral bed nucleus of the str
PMID 25851307

Japanese Journal

Three types of neurochemical projection from the bed nucleus of the stria terminalis to the ventral tegmental area in adult mice.

Kudo Takehiro,Uchigashima Motokazu,Miyazaki Taisuke,Konno Kohtarou,Yamasaki Miwako,Yanagawa Yuchio,Minami Masabumi,Watanabe Masahiko
The Journal of neuroscience : the official journal of the Society for Neuroscience 32(50), 18035-18046, 2012-12-12
… Dopaminergic (DAergic) neurons in the ventral tegmental area (VTA) play crucial roles in motivational control of behaviors, and their activity is regulated directly or indirectly via GABAergic neurons by extrinsic afferents from various sources, including the bed nucleus of the stria terminalis (BST). …
NAID 120005295651

Three Types of Neurochemical Projection from the Bed Nucleus of the Stria Terminalis to the Ventral Tegmental Area in Adult Mice

Kudo Takehiro,Uchigashima Motokazu,Miyazaki Taisuke,Konno Kohtarou,Yamasaki Miwako,Yanagawa Yuchio,Minami Masabumi,Watanabe Masahiko
Journal of Neuroscience 32(50), 18035-18046, 2012-12-12
… Dopaminergic (DAergic) neurons in the ventral tegmental area (VTA) play crucial roles in motivational control of behaviors, and their activity is regulated directly or indirectly via GABAergic neurons by extrinsic afferents from various sources, including the bed nucleus of the stria terminalis (BST). …
NAID 120005295648

痛みによる情動変化の脳内メカニズム (特集痛みの神経学 : 末梢神経から脳まで)

南雅文
Brain and nerve : 神経研究の進歩 64(11), 1241-1247, 2012-11-00
NAID 40019487314

Related Pictures

★リンクテーブル★

リンク元	「分界条」「terminal stria」
拡張検索	「nucleus of stria terminalis」「bed nucleus of stria terminalis」
関連記事	「terminal」

「分界条」

Terminal stria
	Dissection of brain-stem. Lateral view. (Stria terminalis labeled at upper right.)
Details
Latin	stria terminalis
Identifiers
NeuroNames	hier-268
NeuroLex ID	Stria terminalis
Dorlands; /Elsevier	s_26/12763050
TA	A14.1.09.275
FMA	61974
	Anatomical terms of neuroanatomy [edit on Wikidata]