English Journal

Melatonin attenuates 60 Co γ-ray-induced hematopoietic, immunological and gastrointestinal injuries in C57BL/6 male mice.

Khan S1,2, Adhikari JS1, Rizvi MA2, Chaudhury NK1.
Environmental toxicology.Environ Toxicol.2016 Mar 7. doi: 10.1002/tox.22254. [Epub ahead of print]
Protection of hematopoietic, immunological, and gastrointestinal injuries from deleterious effects of ionizing radiation is prime rational for developing radioprotector. The objective of this study, therefore, was to evaluate the radioprotective potential of melatonin against damaging effects of rad
PMID 26948951

Assessing the systemic toxicity in rabbits after sub acute exposure to ocular irritant chemicals.

Reshma CS1, Sruthi S1, Syama S1, Gayathri V1, Mohanan PV1.
Toxicological research.Toxicol Res.2015 Mar;31(1):49-59. doi: 10.5487/TR.2015.31.1.049.
Eye is a highly vascularised organ. There are chances that a foreign substance can enter the systemic circulation through the eye and cause oxidative stress and evoke immune response. Here the eyes of rabbits were exposed, for a period of 7 days, to 5 known ocular irritants: Cetyl pyridinium chlorid
PMID 25874033

Vaccination with Leishmania histone H1-pulsed dendritic cells confers protection in murine visceral leishmaniasis.

Agallou M1, Smirlis D, Soteriadou KP, Karagouni E.
Vaccine.Vaccine.2012 Jul 20;30(34):5086-93. doi: 10.1016/j.vaccine.2012.05.075. Epub 2012 Jun 13.
Visceral leishmaniasis is the most severe form of leishmaniases affecting millions of people worldwide often resulting in death despite optimal therapy. Thus, there is an urgent need for the development of effective anti-infective vaccine(s). In the present study, we evaluated the prophylactic value
PMID 22704924