精祖細胞
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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2014/01/05 21:05:25」(JST)
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Spermatogonium |
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Germinal epithelium of the testicle. 1 basal lamina, 2 spermatogonia, 3 spermatocyte 1st order, 4 spermatocyte 2nd order, 5 spermatid, 6 mature spermatid, 7 Sertoli cell, 8 tight junction (blood testis barrier) |
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Histological section through testicular parenchyma of a boar. 1 Lumen of Tubulus seminiferus contortus, 2 spermatids, 3 spermatocytes, 4 spermatogonia, 5 Sertoli cell, 6 Myofibroblasts, 7 Leydig cells, 8 capillaries |
Gray's |
subject #258 1243 |
MeSH |
Spermatogonia |
A spermatogonium (plural: spermatogonia) is an undifferentiated male germ cell, originating in a seminiferous tubule and dividing into two primary spermatocytes (a kind of germ cell) in the production of spermatozoa.
There are three subtypes:
- Type A(d) cells, with dark nuclei. These cells replicate to ensure a constant supply of spermatogonia to fuel spermatogenesis.
- Type A(p) cells, with pale nuclei. These cells divide by mitosis to produce Type B cells.
- Type B cells, which divide to give rise to primary spermatocytes.
Each primary spermatocyte duplicates its DNA and subsequently undergoes meiosis I to produce two haploid secondary spermatocytes. Each of the two secondary spermatocytes further undergo meiosis II to produce two spermatids (haploid). (1 primary spermatocyte => 4 spermatids)
The spermatids then undergo spermiogenesis to produce spermatozoa.
Additional images[edit]
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Transverse section of a tubule of the testis of a rat. X 250.
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Schematic diagram of Spermatocytogenesis
References[edit]
Male reproductive system (TA A09.3–4, TH H3.07.02, GA 11.1236)
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Internal |
Seminal
tract
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Testes
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- layers
- Tunica vaginalis
- Tunica albuginea
- Tunica vasculosa testis
- Appendix
- Mediastinum
- Lobules
- Septa
- Leydig cell
- Sertoli cell
- Blood-testis barrier
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Spermatogenesis
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- Spermatogonium
- Spermatocytogenesis
- Spermatocyte
- Spermatidogenesis
- Spermatid
- Spermiogenesis
- Spermatozoon
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Other
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- Seminiferous tubules
- Tubuli seminiferi recti
- Rete testis
- Efferent ducts
- Epididymis
- Paradidymis
- Spermatic cord
- Vas deferens
- Ejaculatory duct
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Accessory
glands
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- Seminal vesicles
- Excretory duct of seminal gland
- Prostate
- Urethral crest/Seminal colliculus/Prostatic utricle/Ejaculatory duct
- Prostatic sinus/Prostatic ducts
- Bulbourethral glands
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External |
Penis
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- root
- Crus
- Bulb
- Fundiform ligament
- Suspensory ligament
- body
- Corpus cavernosum
- Corpus spongiosum
- glans
- fascia
- superficial/subcutaneous
- deep/Buck's
- Tunica albuginea
- Septum of the penis
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Urinary
tract
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- Internal urethral orifice
- Urethra
- Prostatic
- Intermediate
- Spongy
- Navicular fossa
- External urethral orifice
- Lacunae of Morgagni
- Urethral gland
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Scrotum
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- layers
- skin
- Dartos
- External spermatic fascia
- Cremaster/Cremasteric fascia
- Internal spermatic fascia
- Perineal raphe
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noco/cong/tumr, sysi/epon
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UpToDate Contents
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- 1. 男性生殖生理学 male reproductive physiology
English Journal
- D-Aspartate Induces Proliferative Pathways in Spermatogonial GC-1 Cells.
- Santillo A1, Falvo S1, Chieffi P2, Di Fiore MM1, Senese R1, Chieffi Baccari G1.
- Journal of cellular physiology.J Cell Physiol.2016 Feb;231(2):490-5. doi: 10.1002/jcp.25095.
- D-aspartate (D-Asp) is an endogenous amino acid present in vertebrate tissues, with particularly high levels in the testis. In vivo studies indicate that D-Asp indirectly stimulates spermatogenesis through the hypothalamic-pituitary-gonadal axis. Moreover, in vitro studies have demonstrated that D-A
- PMID 26189884
- Expression of five acetylcholine receptor subunit genes in Brugia malayi adult worms.
- Li BW1, Rush AC1, Weil GJ1.
- International journal for parasitology. Drugs and drug resistance.Int J Parasitol Drugs Drug Resist.2015 Jun 23;5(3):100-9. doi: 10.1016/j.ijpddr.2015.04.003. eCollection 2015.
- Acetylcholine receptors (AChRs) are required for body movement in parasitic nematodes and are targets of "classical" anthelmintic drugs such as levamisole and pyrantel and of newer drugs such as tribendimidine and derquantel. While neurotransmission explains the effects of these drugs on nematode mo
- PMID 26199859
- Application of three-dimensional culture systems to study mammalian spermatogenesis, with an emphasis on the rhesus monkey (Macaca mulatta).
- Huleihel M1, Nourashrafeddin S, Plant TM2.
- Asian journal of andrology.Asian J Androl.2015 Nov-Dec;17(6):972-80. doi: 10.4103/1008-682X.154994.
- In vitro culture of spermatogonial stem cells (SSCs) has generally been performed using two-dimensional (2D) culture systems; however, such cultures have not led to the development of complete spermatogenesis. It seems that 2D systems do not replicate optimal conditions of the seminiferous tubules (
- PMID 26067870
Japanese Journal
- Characterization and In Vitro Culture of Putative Spermatogonial Stem Cells Derived from Feline Testicular Tissue
- TIPTANAVATTANA Narong,THONGKITTIDILOK Chommanart,TECHAKUMPHU Mongkol [他],THARASANIT Theerawat
- Journal of Reproduction and Development 59(2), 189-195, 2013
- … In experiment 1, testes (n=5) from different pubertal domestic cats were cryosectioned and fluorescently immunolabeled to examine the expression of SSC (GFRα-1), differentiated spermatogonium (c-kit) and germ cell (DDX-4) markers. …
- NAID 130003381843
- Essential Function of Protein 4.1G in Targeting of Membrane Protein Palmitoylated 6 into Schmidt-Lanterman Incisures in Myelinated Nerves
- Terada Nobuo,Saitoh Yurika,Ohno Nobuhiko,Komada Masayuki,Saitoh Sei,Peles Elior,Ohno Shinichi
- MOLECULAR AND CELLULAR BIOLOGY 32(1), 199-205, 2012-01
- … In the seminiferous tubules, MPP6 was localized similarly to protein 4.1G along cell membranes of the spermatogonium and early spermatocytes. …
- NAID 120005440192
- マレーシア産キララシジミ亜科9種(鱗翅目,シジミチョウ科)の染色体調査
- 阿部 東,阿部 玲子
- 蝶と蛾 60(3), 211-221, 2009-09-30
- … jasoda, in spermatogonium, primary and secondary spermatocytes. …
- NAID 110007482600
Related Links
- Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003 ... (spər-māt'ə-gō'nē-əm) Plural spermatogonia Any of the cells of ...
- spermatogonium pl. spermatogonia [Gr.] an undifferentiated male germ cell, originating in a seminal tubule and dividing into a new generation of spermatogonia or into two spermatocytes. sper·ma·to·go·ni·um (sper'mă-tō-gō'nē-ŭm), ...
Related Pictures
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- 英
- spermatogonium (Z), spermatogone
- 関
- 精祖幹細胞、精母細胞。精原細胞。曲精細管
分類