somatostatin receptors

WordNet

1. a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response

PrepTutorEJDIC

1. =sense organ / 受信装置

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/11/08 00:32:00」(JST)

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somatostatin receptor 1
Identifiers
Symbol	SSTR1
Entrez	6751
HUGO	11330
OMIM	182451
RefSeq	NM_001049
UniProt	P30872
Other data
Locus	Chr. 14 q13

somatostatin receptor 2
Identifiers
Symbol	SSTR2
Entrez	6752
HUGO	11331
OMIM	182452
RefSeq	NM_001050
UniProt	P30874
Other data
Locus	Chr. 17 q24

somatostatin receptor 3
Identifiers
Symbol	SSTR3
Entrez	6753
HUGO	11332
OMIM	182453
RefSeq	NM_001051
UniProt	P32745
Other data
Locus	Chr. 22 q13.1

somatostatin receptor 4
Identifiers
Symbol	SSTR4
Entrez	6754
HUGO	11333
OMIM	182454
RefSeq	NM_001052
UniProt	P31391
Other data
Locus	Chr. 20 p11.2

somatostatin receptor 5
Identifiers
Symbol	SSTR5
Entrez	6755
HUGO	11334
OMIM	182455
RefSeq	NM_001053
UniProt	P35346
Other data
Locus	Chr. 16 p13.3

There are five known somatostatin receptors:

• SST₁ (SSTR1)
• SST₂ (SSTR2)
• SST₃ (SSTR3)
• SST₄ (SSTR4)
• SST₅ (SSTR5)

All are G protein-coupled seven transmembrane receptors.

References

External links

• Somatostatin Receptor at the US National Library of Medicine Medical Subject Headings (MeSH)

UpToDate Contents

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• 1. ソマトスタチンの生理学とその類縁体 physiology of somatostatin and its analogues
• 2. Somatostatinoma: Clinical manifestations, diagnosis, and management
• 3. 膵神経内分泌腫瘍（膵島細胞腫瘍）の分類、疫学、臨床症状、局在、および病期分類 classification epidemiology clinical presentation localization and staging of pancreatic neuroendocrine tumors islet cell tumors
• 4. 原発不明の神経内分泌腫瘍 neuroendocrine cancer of unknown primary site
• 5. カルチノイド症候群および腫瘍局在の診断 diagnosis of the carcinoid syndrome and tumor localization

English Journal

• Priming increases the anti-tumor effect and therapeutic window of 177Lu-octreotate in nude mice bearing human small intestine neuroendocrine tumor GOT1.

• Dalmo J1, Spetz J2, Montelius M2, Langen B2, Arvidsson Y3, Johansson H2, Parris TZ4, Helou K4, Wängberg B5, Nilsson O3, Ljungberg M2, Forssell-Aronsson E2.
• EJNMMI research.EJNMMI Res.2017 Dec;7(1):6. doi: 10.1186/s13550-016-0247-y. Epub 2017 Jan 5.
• PMID 28097640

• Effects of somatostatin and its analogues on progenitor mesenchymal cells isolated from human pituitary adenomas.

• Orciani M1, Caffarini M2, Sorgentoni G2, Ricciuti RA3, Arnaldi G4, Di Primio R2.
• Pituitary.Pituitary.2017 Apr;20(2):251-260. doi: 10.1007/s11102-016-0770-x.
• PMID 27796709

• Distribution of type I corticotropin-releasing factor (CRF1) receptors on GABAergic neurons within the basolateral amygdala.

• Calakos KC1, Blackman D1, Schulz AM1, Bauer EP1.
• Synapse (New York, N.Y.).Synapse.2017 Apr;71(4). doi: 10.1002/syn.21953. Epub 2017 Feb 20.
• PMID 27997737

Japanese Journal

• Medical Management of Functioning Pituitary Adenoma: An Update

• Neurologia medico-chirurgica, 2014
• NAID 130004922291

• Medical Management of Functioning Pituitary Adenoma: An Update

• Neurologia medico-chirurgica 54(12), 958-965, 2014
• NAID 130004704540

• 痛みの解剖学：私たちが歩んだ道

• PAIN RESEARCH 28(4), 197-217, 2013
• NAID 130004651944

Related Links

• Somatostatin and the Somatostatin Receptors

Pathways No.2 Spring 2006 www.alomone.com 26 Signal Transduction of Somatostatin Receptors As mentioned above, the SSTRs are members of the GPCR superfamily and as such modulate cellular function through multiple ...

• Somatostatin receptors | G protein-coupled receptors ...

Somatostatin (somatotropin release inhibiting factor) is an abundant neuropeptide, which acts on five subtypes of somatostatin receptor (sst 1-sst 5; nomenclature as agreed by the NC-IUPHAR Subcommittee on Somatostatin ...

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