sodium-bicarbonate cotransporter

• ナトリウム・炭酸水素イオン共輸送体、Na+/HCO3-共輸送体

関

Na-HCO3 cotransporter、Na+-HCO3- cotransporter、sodium-bicarbonate symporter

WordNet

1. a silvery soft waxy metallic element of the alkali metal group; occurs abundantly in natural compounds (especially in salt water); burns with a yellow flame and reacts violently in water; occurs in sea water and in the mineral halite (rock salt) (同)Na, atomic number 11
2. a salt of carbonic acid (containing the anion HCO3) in which one hydrogen atom has been replaced; an acid carbonate (同)hydrogen_carbonate

PrepTutorEJDIC

1. ソジウム,ナトリウム(金属元素;化学記号はNa)
2. 重炭酸塩

UpToDate Contents

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• 1. 腎尿細管性アシドーシスの概要と病態生理、およびカリウムバランスへの影響 overview and pathophysiology of renal tubular acidosis and the effect on potassium balance
• 2. 成人における代謝性アシドーシスへのアプローチ approach to the adult with metabolic acidosis
• 3. 乳酸アシドーシスにおける重炭酸療法 bicarbonate therapy in lactic acidosis
• 4. 乳児や小児の尿細管性アシドーシスの病因および臨床症状 etiology and clinical manifestations of renal tubular acidosis in infants and children
• 5. 成人における高カリウム血症の治療および予防 treatment and prevention of hyperkalemia in adults

English Journal

• Bicarbonate sensing in mouse cortical astrocytes during extracellular acid/base disturbances.

• Theparambil SM1, Naoshin Z1, Defren S1, Schmaelzle J1, Weber T1, Schneider HP1, Deitmer JW1.
• The Journal of physiology.J Physiol.2016 Dec 16. doi: 10.1113/JP273394. [Epub ahead of print]
• Extracellular acid/base status of the mammalian brain undergoes dynamic changes during many physiological and pathological events. Although intracellular pH of astrocytes responds to the alteration of extracellular acid/base changes, mechanisms mediating these changes have remained unresolved. We ha
• PMID 27981578

• Influence of training intensity on adaptations in acid/base transport proteins, muscle buffer capacity, and repeated-sprint ability in active men.

• McGinley C1, Bishop DJ2,3.
• Journal of applied physiology (Bethesda, Md. : 1985).J Appl Physiol (1985).2016 Dec 1;121(6):1290-1305. doi: 10.1152/japplphysiol.00630.2016. Epub 2016 Oct 14.
• McGinley C, Bishop DJ. Influence of training intensity on adaptations in acid/base transport proteins, muscle buffer capacity, and repeated-sprint ability in active men. J Appl Physiol 121: 1290-1305, 2016. First published October 14, 2016; doi:10.1152/japplphysiol.00630.2016-This study measured the
• PMID 27742804

• Oncogenic p95HER2 regulates Na+-HCO3- cotransporter NBCn1 mRNA stability in breast cancer cells via 3'UTR-dependent processes.

• Gorbatenko A1, Olesen CW1, Loebl N1, Sigurdsson HH1, Bianchi C1, Pedraz-Cuesta E1, Christiansen J2, Pedersen SF1.
• The Biochemical journal.Biochem J.2016 Nov 1;473(21):4027-4044. Epub 2016 Sep 8.
• The Na+-HCO3- cotransporter NBCn1 (SLC4A7) is up-regulated in breast cancer, important for tumor growth, and a single nucleotide polymorphism (SNP), rs4973768, in its 3' untranslated region (3'UTR) correlates with increased breast cancer risk. We previously demonstrated that NBCn1 expression and pro
• PMID 27609814

Japanese Journal

• Regulation of the sodium bicarbonate cotransporter kNBC1 function : role of Asp (986), Asp (988) and kNBC1-carbonic anhydrase II binding

• J Physiol (Lond) 544, 679-685, 2002
• NAID 30022484994

• Molecular cloning, chromosomal localization, tissue distribution, and functional expression of the human pancreatic sodium bicarbonate cotransporter

• J. Biol. Chem. 273, 17689-17695, 1998
• NAID 80010436882

• Molecular cloning, chromosomal localization, tissue distribution, and functional expression of the human pancreatic sodium bicarbonate cotransporter

• J Biol Chem 273, 17689-17695, 1998
• NAID 30016325872

Related Links

• SLC4A4 solute carrier family 4 member 4 [ (human)]

This gene encodes a sodium bicarbonate cotransporter (NBC) involved in the regulation of bicarbonate secretion and absorption and intracellular pH. Mutations in this gene are associated with proximal renal tubular ...

• The Sodium Bicarbonate Cotransporter: Structure, Function ...

In summary, cellular, tissue and organ functions are impacted by any abnormality of these transporters. The sodium bicarbonate cotransporter plays an indispensable role in the regulation of intracellular pH. Abnormalities in NBC

• Slc4a7 - Sodium bicarbonate cotransporter 3 - Rattus ...

Electroneutral sodium- and bicarbonate-dependent cotransporter with a Na(+):HCO3(-) 1:1 stoichiometry. Regulates intracellular pH and may play a role in bicarbonate salvage in secretory epithelia. May also have an associated ...

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★リンクテーブル★

リンク元	「Na+-HCO3- cotransporter」「sodium-bicarbonate symporter」「Na+/HCO3-共輸送体」「ナトリウム・炭酸水素イオン共輸送体」
関連記事	「cotransport」「cotransporter」「sodium bicarbonate」

「Na+-HCO3- cotransporter」

　　[★]

• Na+/HCO3-共輸送体、ナトリウム・炭酸水素イオン共輸送体

関

Na-HCO3 cotransporter、sodium-bicarbonate cotransporter、sodium-bicarbonate symporter

「sodium-bicarbonate symporter」

　　[★]

• ナトリウム・炭酸水素イオン共輸送体、Na+/HCO3-共輸送体

関

Na-HCO3 cotransporter、Na+-HCO3- cotransporter、sodium-bicarbonate cotransporter

「Na+/HCO3-共輸送体」

　　[★]

英

Na+-HCO3- cotransporter、sodium-bicarbonate cotransporter、sodium-bicarbonate symporter

関

ナトリウム・炭酸水素イオン共輸送体

「ナトリウム・炭酸水素イオン共輸送体」

　　[★]

英

sodium-bicarbonate cotransporter、sodium-bicarbonate symporter、Na+-HCO3- cotransporter

関

Na+/HCO3-共輸送体

「cotransport」

　　[★]

• 共輸送、等方輸送、共輸送する

関

co-transport、symport

「cotransporter」

　　[★]

• 共輸送体、コトランスポーター

関

co-transporter、symporter

「sodium bicarbonate」

　　[★] 炭酸水素ナトリウム