small ubiquitin-like modifier

• 低分子ユビキチン様修飾因子

関

small ubiquitin-related modifier、SUMO

WordNet

1. want to have; "Id like a beer now!"
2. a kind of person; "Well not see his like again"; "I cant tolerate people of his ilk" (同)ilk
3. a similar kind; "dogs, foxes, and the like", "we dont want the likes of you around here" (同)the like, the likes of
4. equal in amount or value; "like amounts"; "equivalent amounts"; "the same amount"; "gave one six blows and the other a like number"; "the same number" (同)same
5. resembling or similar; having the same or some of the same characteristics; often used in combination; "suits of like design"; "a limited circle of like minds"; "members of the cat family have like dispositions"; "as like as two peas in a pod"; "doglike devotion"; "a dreamlike quality" (同)similar
6. be fond of; "I like my nephews"
7. feel about or towards; consider, evaluate, or regard; "How did you like the Presidents speech last night?"
8. find enjoyable or agreeable; "I like jogging"; "She likes to read Russian novels"
9. slight or limited; especially in degree or intensity or scope; "a series of death struggles with small time in between"
10. a garment size for a small person
11. the slender part of the back
12. limited or below average in number or quantity or magnitude or extent; "a little dining room"; "a little house"; "a small car"; "a little (or small) group" (同)little
13. have fine or very small constituent particles; "a small misty rain"
14. on a small scale; "think small"
15. a gene that modifies the effect produced by another gene (同)modifier_gene
16. a content word that qualifies the meaning of a noun or verb (同)qualifier
17. a moderator who makes less extreme or uncompromising
18. a feeling of pleasure and enjoyment; "Ive always had a liking for reading"; "she developed a liking for gin"
19. found pleasant or attractive; often used as a combining form; "a well-liked teacher"

PrepTutorEJDIC

1. …‘を'『好む』,‘が'好きである / 《しばしば否定文で,またwould,《英》shouldと共に用いて》…‘を'望む,…したい / 『好む』;望む / 《複数形で》好み,好きな事
2. (外観・性質などが)…『に似た』,のような / (やり方,程度などが)…『と同じように』 / …『らしい』,にふさわいし / 《おもに話》たとえば…のような / 《名詞の前にのみ用いて》(性質・外観などが)同じの,(数量が)等しい / 《補語にのみ用いて》似ている,そっくりで / たぶん,おそらく(probably) / (…に)似た人(物),(…と)同等の人(物),匹敵する人(物)《+『of』+『名』》 / …のように / あたかも…のように
3. (大きさが)『小さい』,小形の;(量が)『少ない』,わずかな / 『取るに足りない』,ささいな(trivial) / 《名詞の前にのみ用いて》(仕事・活動などが)『小規模の』,ささやかな / 心が狭い,利己的な / (音・声が)弱い,小さい / (文字が)小型の,小文字の / 《the~》小さいもの;(…の)細い部分《+『of』+『名』》 / 《複数形で》《英》(衣類・ハンカチなどの)小物,小間物 / 小さく,細かく / (声などが)低く,弱く / 小規模に,こぢんまりと
4. 修飾語[句](形容詞・副詞など)
5. (…の)『好み』,趣味《+『for』(『to』)+『名』》

UpToDate Contents

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English Journal

• Spatiotemporal distribution of SUMOylation components during mouse brain development.

• Hasegawa Y1, Yoshida D, Nakamura Y, Sakakibara S.
• The Journal of comparative neurology.J Comp Neurol.2014 Sep 1;522(13):3020-36. doi: 10.1002/cne.23563.
• Posttranslational modification of proteins might play an important role in brain cellular dynamics via the rapid turnover or functional change of critical proteins controlling neuronal differentiation or synaptic transmission. Small ubiquitin-like modifier protein (SUMO) is a family of ubiquitin-lik
• PMID 24639124

• Structural analysis of poly-SUMO chain recognition by the RNF4-SIMs domain.

• Kung CC, Naik MT1, Wang SH2, Shih HM1, Chang CC3, Lin LY4, Chen CL, Ma C4, Chang CF4, Huang TH.
• The Biochemical journal.Biochem J.2014 Aug 15;462(1):53-65. doi: 10.1042/BJ20140521.
• The E3 ubiquitin ligase RNF4 (RING finger protein 4) contains four tandem SIM [SUMO (small ubiquitin-like modifier)-interaction motif] repeats for selective interaction with poly-SUMO-modified proteins, which it targets for degradation. We employed a multi-faceted approach to characterize the struct
• PMID 24844634

• Multiple Arkadia/RNF111 Structures Coordinate Its Polycomb Body Association and Transcriptional Control.

• Sun H1, Liu Y2, Hunter T1.
• Molecular and cellular biology.Mol Cell Biol.2014 Aug 15;34(16):2981-95. doi: 10.1128/MCB.00036-14. Epub 2014 Jun 9.
• The RING domain protein Arkadia/RNF111 is a ubiquitin ligase in the transforming growth factor β (TGFβ) pathway. We previously identified Arkadia as a small ubiquitin-like modifier (SUMO)-binding protein with clustered SUMO-interacting motifs (SIMs) that together form a SUMO-binding domain (SBD).
• PMID 24912682

Japanese Journal

• Expression and characterization of SUMO-conjugated metal-responsive transcription factor 1 : SIM-dependent cross-interaction and distinct DNA binding activity

• Lin Chang-Yi,Liu Ya-Chuan,Lin Meng-Chieh [他]
• The journal of biochemistry 153(4), 361-369, 2013-04
• NAID 40019622699

• イネSUMO遺伝子の単離および発現と細胞局在性の解析

• 五十嵐 雄太,野口 夏希,ATTIA Kotb [他],北島-古賀 彩,三ツ井 敏明,伊藤 紀美子,Ikarashi Yuta,Noguchi Natsuki,Attia Kotb,Kitajima-Koga Aya,Mitsui Toshiaki,Itoh Kimiko
• 新潟大学農学部研究報告 65(1), 77-83, 2012-09
• … Small ubiquitin-related modifier (SUMO) is a type of ubiquitin-like proteins and regulates various protein functions through post-translational modification. … In the case of DsRed:SUMO3, the DsRed signal was detected mainly in nucleus, and formed sub-nuclear domain like structure. …
• NAID 120005285466

• All the Little Pieces : Regulation of Mitochondrial Fusion and Fission by Ubiquitin and Small Ubiquitin-Like Modifier and Their Potential Relevance in the Heart

• ZUNGU Makhosazan,SCHISLER Jonathan,WILLIS Monte S.
• Circulation journal : official journal of the Japanese Circulation Society 75(11), 2513-2521, 2011-10-25
• … In this review, we discuss how these proteins are regulated by post-translational modification with ubiquitin and SUMO (small ubiquitin-like modifier). … We then present what is known about the ubiquitin and SUMO ligases that regulate these post-translational modifications and regulation of mitochondrial fusion and fission, exploring their potential as therapeutic targets of cardiac disease. …
• NAID 10030031649

Related Links

• SUMO protein - Wikipedia, the free encyclopedia

Small Ubiquitin-like Modifier (or SUMO) proteins are a family of small proteins that are covalently attached to and detached from other proteins in cells to modify their function. SUMOylation is a post-translational modification involved in various ...

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★リンクテーブル★

リンク元	「SUMO」「低分子ユビキチン様修飾因子」「small ubiquitin-related modifier」
関連記事	「like」「modifier」「small」

「SUMO」

　　[★]

• 低分子ユビキチン様修飾因子、ユビキチン様タンパク質

関

small ubiquitin-like modifier、small ubiquitin-related modifier、ubiquitin-like protein

「低分子ユビキチン様修飾因子」

　　[★]

英

small ubiquitin-related modifier、small ubiquitin-like modifier、SUMO

関

ユビキチン様タンパク質

「small ubiquitin-related modifier」

　　[★]

• 低分子ユビキチン様修飾因子

関

small ubiquitin-like modifier、SUMO

「like」

　　[★]

• v.

• 好む

• prep.

• 似ている、同様の

関

alike、as well as、care for、correspond、correspondingly、equally、favor、identically、likewise、prefer、resemble、same、similar、similarly、such

　 　 　 　 　 　 　 　 　 　

「modifier」

　　[★]

• n.

• 修飾因子、変更因子、(遺伝子;表現型に影響する因子)モディファイヤー

関

effect modifier、modifying factor、modulator

　 　 　 　

「small」

　　[★]

• adj.

• 小さい

関

little、petit、tiny