WordNet
- the quality of being changeable in direction; "the shiftiness of the wind caused the boat to veer unpredictably"
PrepTutorEJDIC
- やりくりのうまさ;ずるさ
English Journal
- Programmed translational -1 frameshifting on hexanucleotide motifs and the wobble properties of tRNAs.
- Licznar P1, Mejlhede N, Prère MF, Wills N, Gesteland RF, Atkins JF, Fayet O.
- The EMBO journal.EMBO J.2003 Sep 15;22(18):4770-8.
- Programmed -1 ribosomal frameshifting, involving tRNA re-pairing from an AAG codon to an AAA codon, has been reported to occur at the sequences CGA AAG and CAA AAG. In this study, using the recoding region of insertion sequence IS3, we have investigated the influence on frameshifting in Escherichia
- PMID 12970189
- 1-Methylguanosine in place of Y base at position 37 in phenylalanine tRNA is responsible for its shiftiness in retroviral ribosomal frameshifting.
- Carlson BA1, Mushinski JF, Henderson DW, Kwon SY, Crain PF, Lee BJ, Hatfield DL.
- Virology.Virology.2001 Jan 5;279(1):130-5.
- Many mammalian retroviruses express their protease and polymerase by ribosomal frameshifting. It was originally proposed that a specialized shifty tRNA promotes the frameshift event. We previously observed that phenylalanine tRNA(Phe) lacking the highly modified wybutoxosine (Y) base on the 3' side
- PMID 11145896
- Yeast asparagine (Asn) tRNA without Q base promotes eukaryotic frameshifting more efficiently than mammalian Asn tRNAs with or without Q base.
- Carlson BA1, Kwon SY, Lee BJ, Hatfield D.
- Molecules and cells.Mol Cells.2000 Feb 29;10(1):113-8.
- In this study, we compare the efficiency of Asn tRNA from mammalian sources with and without the highly modified queuosine (Q) base in the wobble position of its anticodon and Asn tRNA from yeast, which naturally lacks Q base, to promote frameshifting. Interestingly, no differences in the ability of
- PMID 10774757
Related Links
- shift·y (sh f t ). adj. shift·i·er, shift·i·est. 1. Having, displaying, or suggestive of deceitful character; evasive or untrustworthy. 2. Distinguished by frequent changes in direction: shifty winds. 3. Able to accomplish what is needed; resourceful.
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