Harvard business review.Harv Bus Rev.2011 Apr;89(4):76-83, 137.
It's hardly news that business leaders work in increasingly uncertain environments, where failures are bound to be more common than successes. Yet if you ask executives how well, on a scale of one to 10, their organizations learn from failure, you'll often get a sheepish "Two-or maybe three" in resp
Sheepish B cells: evidence for antigen-independent antibody diversification in humans and mice.
Tarlinton D.
The Journal of experimental medicine.J Exp Med.2008 Jun 9;205(6):1251-4. doi: 10.1084/jem.20081057. Epub 2008 Jun 2.
Antibody diversity is first generated by rearrangement of immunoglobulin (Ig) genes during B cell development in the bone marrow, and later by antigen-driven diversification in germinal centers (GCs). New data in humans and mice now identify specific B cell populations that may have undergone antige
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