糖尿病性浮腫性硬化症
WordNet
- a skin disease marked by hard edema of the tissue usually beginning in the face
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/10/14 19:39:40」(JST)
[Wiki en表示]
Not to be confused with Scleroderma.
| Scleredema |
| Classification and external resources |
| Specialty |
rheumatology, pediatrics |
| ICD-10 |
M34.8, P83.0 |
| DiseasesDB |
31361 |
| eMedicine |
article/1066175 |
| MeSH |
D012592 |
Scleredema, also known as Buschke disease, scleredema of Buschke, and scleredema adultorum,[1][2] is a rare, self-limiting skin condition defined by progressive thickening and hardening of the skin, usually on the areas of the upper back, neck, shoulders and face.[3] The skin may also change color to red or orange. The disease was discovered by Abraham Buschke. Although the cause of scleredema is unknown, it is usually associated with a disease, usually diabetes,[4] a viral illness or strep throat.[5] It is usually not fatal, but it may cause death if the disease spreads to the internal organs.[3] It may also cause an infection.[5]
Contents
- 1 Diagnosis
- 2 Treatment
- 3 See also
- 4 References
Diagnosis
The scleredema is usually proposed as a diagnosis based on the appearance of the skin and the patient's medical history. To confirm the diagnosis, the doctor performs a skin biopsy, in which hematoxylin and eosin staining will show a thick reticular dermis with thick collagen bundles separated by clear spaces.[6] The patient's blood may be examined for diseases that may appear after the onset of symptoms, such as multiple myeloma.[5]
Treatment
Although many types of medications have been tried as treatments, none of them have been proven effective in treating scleredema. Those treatments, such as corticosteroids, may benefit the patient, but will not cure their condition. If the affected area is infected, it is usually treated immediately. The symptoms of the condition usually resolve within six months to two years after onset. However, patients whose condition was associated to diabetes may suffer for longer periods of time.[5]
Myocarditis resulting as a complication from the disease has been successfully treated with penicillin and steroids.[7]
See also
References
- ^ Turchin I, Adams SP, Enta T (September 2003). "Dermacase. Scleredema adultorum, or Bushke disease". Can Fam Physician 49: 1089, 1093. PMC 2214291. PMID 14526859.
- ^ Pegum JS (June 1972). "Scleredema of Buschke". Proc. R. Soc. Med. 65 (6): 528. PMC 1643957. PMID 5044976.
- ^ a b "Scleredema". Retrieved 2009-05-18.
- ^ Meguerditchian, C; Jacquet P; Béliard S; et al. (November 2006). "Scleredema adultorum of Buschke: an under recognized skin complication of diabetes". Diabetes and Metabolism 32 (5): 481–484. doi:10.1016/S1262-3636(07)70307-5. PMID 17110904.
- ^ a b c d "Scleredema". Retrieved 2009-05-18.
- ^ Schmults CA (October 2003). "Scleredema". Dermatol. Online J. 9 (4): 11. PMID 14594584.
- ^ "Buschke's Sclerema with right-sided heart failure.". Retrieved 2009-05-18.
UpToDate Contents
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English Journal
- Tran K, Boyd KP, Robinson MR, Whitlow M.Author information New York University School of Medicine.AbstractWe present a case of scleredema with a leonine facies in a 56-year-old man with a history of poorly controlled diabetes mellitus. The patient initially presented with erythematous, edematous papules and plaques on the face, neck, and upper back.
- Dermatology online journal.Dermatol Online J.2013 Dec 16;19(12):20718.
- We present a case of scleredema with a leonine facies in a 56-year-old man with a history of poorly controlled diabetes mellitus. The patient initially presented with erythematous, edematous papules and plaques on the face, neck, and upper back.
- PMID 24365009
- Dermatologic manifestations of diabetes mellitus: a review.
- Murphy-Chutorian B, Han G, Cohen SR.Author information University of California, Irvine, Irvine, CA 92697, USA.AbstractDiabetes mellitus affects every organ of the body including the skin. Certain skin manifestations of diabetes are considered cutaneous markers of the disease, whereas others are nonspecific conditions that occur more frequently among individuals with diabetes compared with the general population. Diabetic patients have an increased susceptibility to some bacterial and fungal skin infections, which account, in part, for poor healing. Skin complications of diabetes provide clues to current and past metabolic status. Recognition of cutaneous markers may slow disease progression and ultimately improve the overall prognosis by enabling earlier diagnosis and treatment.
- Endocrinology and metabolism clinics of North America.Endocrinol Metab Clin North Am.2013 Dec;42(4):869-98. doi: 10.1016/j.ecl.2013.07.004.
- Diabetes mellitus affects every organ of the body including the skin. Certain skin manifestations of diabetes are considered cutaneous markers of the disease, whereas others are nonspecific conditions that occur more frequently among individuals with diabetes compared with the general population. Di
- PMID 24286954
- Complete remission of multiple myeloma associated scleredema after bortezomib-based treatment.
- Szturz P, Adam Z, Vašků V, Feit J, Krejčí M, Pour L, Hájek R, Mayer J.
- Leukemia & lymphoma.Leuk Lymphoma.2013 Jun;54(6):1324-6. doi: 10.3109/10428194.2012.738816. Epub 2012 Nov 15.
- PMID 23061634
Japanese Journal
- Scleredema diabeticorum successfully treated with ultraviolet A1 phototherapy
Related Links
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★リンクテーブル★
[★]
- 英
- diabetic scleredema
- ラ
- scleredema diabeticorum
- 関
- 浮腫性硬化症、糖尿病性浮腫性硬化症