English Journal

Evaluation of diuretic activity of Amaranthus spinosus Linn. aqueous extract in Wistar rats.

Amuthan A, Chogtu B, Bairy KL, Sudhakar, Prakash M.SourceDepartment of Pharmacology, Melaka Manipal Medical College (Manipal Campus), Manipal University, Manipal 576104, Karnataka, India.
Journal of ethnopharmacology.J Ethnopharmacol.2012 Mar 27;140(2):424-7. doi: 10.1016/j.jep.2012.01.049. Epub 2012 Feb 6.
ETHNOPHARMACOLOGICAL RELEVANCE: Traditional Siddha medicine literature claims that the Amaranthus spinosus Linn. (family: Amaranthaceae) whole plant possesses diuretic property.AIM OF THE STUDY: To evaluate the diuretic potential of Amaranthus spinosus aqueous extract (ASAE) in rats.MATERIAL AND MET
PMID 22331031

Natriuretic and saluretic effects of Hemidesmus indicus R. Br. root extracts in rats.

Gadge NB, Jalalpure SS.SourceDepartment of Pharmacognosy and Phytochemistry, KLE University's College of Pharmacy, JNMC Campus, Nehru Nagar, Belgaum- 590 010, Karnataka, India.
Indian journal of pharmacology.Indian J Pharmacol.2011 Nov;43(6):714-7. doi: 10.4103/0253-7613.89833.
OBJECTIVE: The present study was aimed to investigate the diuretic effects of aqueous (AqE) and ethanolic (EtE) crude extracts of Hemidesmus indicus R. Br. roots (family - Asclepiadaceae) using acute model in rats.MATERIALS AND METHODS: A single individual dose of AqE and EtE of H. indicus root (200
PMID 22144781

Jadhav RB, Bhatnagar SP, Surana SJ.SourceBioecology Laboratory, Department of Pharmacognosy, R.C. Patel Institute of Pharmaceutical Education and Research, Shirpur, India. ramjadhav123@yahoo.co.in
Pharmaceutical biology.Pharm Biol.2010 Apr;48(4):417-21. doi: 10.3109/13880200903150427.
Viscum angulatum Heyne ex DC (Viscaceae) is a leafless hemiparasitic shrub traditionally used in Asian countries for the treatment of hypertension. In the present study, the methanol extract of the whole plant was examined for diuretic activity in rats. The activity was evaluated using parameters su
PMID 20645720

Japanese Journal

Kau Sen,Yochim Christopher,Do My Linh,Leszczynska Krystyna,Andruskiewicz Chester,Schwartz Jack,Li Jack,Howe Burton
The Japanese Journal of Pharmacology 57(3), 263-277, 1991
… In conscious dogs, the saluretic activity of ICI d-181, 037 (5 mg/kg, p.o.) was about 80% of the corresponding hydrochlorothiazide value, whereas the 1-isomer demonstrated only minimum saluretic activity. …
NAID 130000833229

TANAKA Satoru,KANDA Akira,ASHIDA Shin-ichiro
The Japanese Journal of Pharmacology 54(3), 307-314, 1990
… These results suggest that DR-3438 exerts uricosuric activity through blocking urate transport in the proximal tubules and diuretic and saluretic activities by inhibiting water and sodium reabsorption in the distal segment of the nephron. …
NAID 130000832944

Studies on Uricosuric Diuretics. II. : 6,7-Dichloro-4-nitro-, 6,7-Dichloro-4-sulfamoyl- and 6,7-Dichloro-4-acyl-2,3-dihydrobenzofuran-2-carboxylic Acids(Medeicinal Chemistry,Chemical)

HARADA HIROSHI,MATSUSHITA YOSHIHIRO,YODO MITSUAKI,NAKAMURA MASUHISA,YONETANI YUKIO
Chemical & pharmaceutical bulletin 35(8), 3215-3226, 1987-08-25
… 2,3-Dihydrobenzofuran-2-carboxylic acids substituted with electronegative nitro, acyl and sulfamoyl groups at the 4-position were synthesized and tested for oral diuretic and saluretic activities in rats and mice. … The 4-nitro compounds (11b, 12b, 13b and 14b) showed more potent saluretic activity than the corresponding 5-nitro compounds (7b, 18b, 19b and 20). … Although the 5-acyl compounds were reported to show potent saluretic activities, the 4-acyl compounds (41a and b) had much lower activities. …
NAID 110006281399