English Journal

Effects of tolvaptan on systemic and renal hemodynamic function in dogs with congestive heart failure.

Onogawa T1, Sakamoto Y, Nakamura S, Nakayama S, Fujiki H, Yamamura Y.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy.Cardiovasc Drugs Ther.2011 Dec;25 Suppl 1:S67-76. doi: 10.1007/s10557-011-6350-4.
PURPOSE: We investigated the effects of tolvaptan, a vasopressin V(2)-receptor antagonist, on diuretic response and systemic and renal hemodynamic characteristics in conscious dogs with congestive heart failure (CHF). We also compared these effects with those of furosemide, a loop diuretic.METHODS:
PMID 22120095

[Influence of the angiotensin converting enzyme inhibition on the functional proteinuria in rats].

Kutina AV, Natochin IuV, Shakhmatova EI.
Rossiĭskii fiziologicheskiĭ zhurnal imeni I.M. Sechenova / Rossiĭskaia akademiia nauk.Ross Fiziol Zh Im I M Sechenova.2009 Oct;95(10):1151-9.
Influence of enalaprilat, angiotensin converting enzyme inhibitor, on a functional proteinuria associated with increase in diuresis unduced by furosemide, 1-deamino-arginine vasotocin (1d-AVT) injection or water loading was investigated in experiments with Wistar rats. Intraperitoneal injection of 0
PMID 19957902

Sindić A1, Schlatter E.
Current opinion in nephrology and hypertension.Curr Opin Nephrol Hypertens.2007 Jan;16(1):10-5.
PURPOSE OF REVIEW: Guanylin peptides are secreted from the intestine and influence electrolyte and water transport in intestine and kidney, suggesting that these peptides act as intestinal natriuretic peptides. This review presents recent research on renal guanylin and uroguanylin effects.RECENT FIN
PMID 17143065

Japanese Journal

Kau Sen,Yochim Christopher,Do My Linh,Leszczynska Krystyna,Andruskiewicz Chester,Schwartz Jack,Li Jack,Howe Burton
The Japanese Journal of Pharmacology 57(3), 263-277, 1991
… In saline-loaded rats, the magnitude of water diuresis and saluresis produced by ICI 181, 037 (10 mg/kg, p.o.) was equal to that of hydrochlorothiazide. … Water diuresis and saluresis produced by ICI 181, 037 were enhanced with SKF 525A, ampicillin or neomycin plus lincomycin, suggesting that ICI 181, 037 is an active diuretic. …
NAID 130000833229

A new diuretic that does not reduce renal handling of uric acid in rats, S-8666.

YONETANI Yukio,IWAKI Kazumi,ISHII Mitsuo,HARADA Hiroshi
The Japanese Journal of Pharmacology 43(4), 399-405, 1987
… Diuretic thiazides such as trichlormethiazide and hydrochlorothiazide and loop diuretics such as furosemide and indacrinone clearly reduced the renal function for uric acid excretion in treatment which produced major effects such as diuresis, saluresis and hypotension. …
NAID 130000833356

Multiple dose comparison of two oral formulations of the Salidiuretic Piretanide.

MÜLLER F. O.,MEYER B. H.,GRIGOLEIT H.-G.,HEPTNER W.,MALERCZYK V.,MERKEL W.
臨床薬理 15(3), 463-468, 1984
… The duration of the diuretic effect is more than doubled in comparison to the standard tablet without loss of overall pharmacodynamic activity (diuresis and saluresis). …
NAID 130002047591