- 関
- retrosynthesis
English Journal
- Modular Synthesis of Constrained Ethyl (cEt) Purine and Pyrimidine Nucleosides.
- Blade H1, Bradley D1, Diorazio L1, Evans T1, Hayter BR1, Howell GP1.
- The Journal of organic chemistry.J Org Chem.2015 May 15;80(10):5337-43. doi: 10.1021/acs.joc.5b00607. Epub 2015 Apr 28.
- A modular and scalable approach to pyrimidine- and purine-containing constrained ethyl (cEt) nucleosides is demonstrated. Minimizing stereochemical adjustments and protecting group manipulations, diacetone glucose is converted to two representative cEt nucleosides via a functionalized, common interm
- PMID 25894018
- Synthesis of the spirastrellolide A, B/C spiroketal: enabling solutions for problematic Au(I)-catalyzed spiroketalizations.
- Butler BB Jr1, Manda JN1, Aponick A1.
- Organic letters.Org Lett.2015 Apr 17;17(8):1902-5. doi: 10.1021/acs.orglett.5b00711. Epub 2015 Apr 3.
- A synthesis of the spirastrellolide A, B/C-ring monounsaturated spiroketal is reported. The key step relies on a Au-catalyzed spiroketalization of a propargyl triol employing an acetonide as a regioselectivity regulator. Through observation and analysis, a set of conditions has been developed that f
- PMID 25839325
- Function through synthesis-informed design.
- Wender PA1, Quiroz RV1, Stevens MC1.
- Accounts of chemical research.Acc Chem Res.2015 Mar 17;48(3):752-60. doi: 10.1021/acs.accounts.5b00004. Epub 2015 Mar 5.
- In 1996, a snapshot of the field of synthesis was provided by many of its thought leaders in a Chemical Reviews thematic issue on "Frontiers in Organic Synthesis". This Accounts of Chemical Research thematic issue on "Synthesis, Design, and Molecular Function" is intended to provide further perspect
- PMID 25742599
Japanese Journal
- MALDI MS-based Composition Analysis of the Polymerization Reaction of Toluene Diisocyanate (TDI) and Ethylene Glycol (EG)
- AHN Yeong Hee,LEE Yeon Jung,KIM Sung Ho
- Analytical Sciences 31(6), 513-520, 2015
- … A new MALDI MS data interpretation method was developed, consisting of a peak-resolving algorithm for overlapping peaks in MALDI MS spectra, a retrosynthetic analysis for the generation of reduced unit mass peaks, and a Gaussian fit-based selection of the most prominent polymer series among the reconstructed unit mass peaks. …
- NAID 130005075715
- Advanced PLS Technique Focusing on Visualization and Chemical Interpretation - SOMPLS Analysis of Serine Protease Inhibitors -
- 長谷川 清,船津 公人
- Journal of Computer Aided Chemistry 11, 56-61, 2010
- … 分子中の特定の部分構造の存在を表すRetrosynthetic Combinatorial Analysis Procedure (RECAP) フラグメントをchemical descriptorとして利用した。 …
- NAID 130004428030
- P-56 クロスカップリングによる共役ジエンの立体選択的合成法の開発とspirofunginC_1-C_9側鎖の合成(ポスター発表の部)
- 宮澤 眞宏,竹端 里紗,横山 初,山口 晴司,平井 美朗
- 天然有機化合物討論会講演要旨集 (50), 707-712, 2008-09-01
- … Retrosynthetic fragmentation of spirofungin A affords three segments. …
- NAID 110007066691
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