(染色体内でRNA中間体を介して転位するトランスポゾン)レトロポゾン
- 関
- retroelement、retrotransposon
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2014/07/16 06:36:06」(JST)
[Wiki en表示]
Phylogenetic tree of marsupials derived from retroposon data
[1]
Retroposons are repetitive DNA fragments which are inserted into chromosomes after they had been reverse transcribed from any RNA molecule. In contrast to retrotransposons, they never encode reverse transcriptase (RT). Therefore, they are non-autonomous elements with regard to transposition activity (as opposed to transposons).
Non-LTR retrotransposons (such as the human L1 elements) are sometimes falsely referred to as retroposons. Retroposition accounts for approximately 10,000 gene-duplication events in the human genome, of which approximately 2-10% are likely to be functional.[2] Such genes are called retrogenes and represent a certain type of retroposon. A classical event is the retroposition of a spliced pre-mRNA molecule of the c-src gene into the proviral ancestor of the Rous Sarcoma Virus (RSV). The retroposed c-src pre-mRNA still contained a single intron and within RSV is now referred to as v-src gene.
References
- ^ Nilsson, M. A.; Churakov, G.; Sommer, M.; Tran, N. V.; Zemann, A.; Brosius, J. R.; Schmitz, J. R. (2010). "Tracking Marsupial Evolution Using Archaic Genomic Retroposon Insertions". PLoS Biology 8 (7): e1000436. doi:10.1371/journal.pbio.1000436. edit
- ^ Emerson JJ, Kaessmann H, Betrán E, Long M (January 2004). "Extensive gene traffic on the mammalian X chromosome". Science 303 (5657): 537–40. doi:10.1126/science.1090042. PMID 14739461.
English Journal
- A self-encoded capsid derivative restricts Ty1 retrotransposition in Saccharomyces.
- Garfinkel DJ1, Tucker JM2, Saha A2, Nishida Y2, Pachulska-Wieczorek K3, Błaszczyk L4, Purzycka KJ3.
- Current genetics.Curr Genet.2016 May;62(2):321-9. doi: 10.1007/s00294-015-0550-6. Epub 2015 Dec 9.
- Retrotransposons and retroviral insertions have molded the genomes of many eukaryotes. Since retroelements transpose via an RNA intermediate, the additive nature of the replication cycle can result in massive increases in copy number if left unchecked. Host organisms have countered with several defe
- PMID 26650614
- MIR retroposon exonization promotes evolutionary variability and generates species-specific expression of IGF-1 splice variants.
- Annibalini G1, Bielli P2, De Santi M3, Agostini D3, Guescini M3, Sisti D3, Contarelli S3, Brandi G3, Villarini A4, Stocchi V3, Sette C2, Barbieri E5.
- Biochimica et biophysica acta.Biochim Biophys Acta.2016 Apr 2. pii: S1874-9399(16)30059-1. doi: 10.1016/j.bbagrm.2016.03.014. [Epub ahead of print]
- Insulin-like growth factor (IGF-1) -1 is a pleiotropic hormone exerting mitogenic and anti-apoptotic effects. Inclusion or exclusion of exon 5 into the IGF-1 mRNA gives rise to three transcripts, IGF-1Ea, IGF-1Eb and IGF-1Ec, which yield three different C-terminal extensions called Ea, Eb and Ec pep
- PMID 27048986
- APOBEC3A damages the cellular genome during DNA replication.
- Green AM1,2, Landry S3, Budagyan K4, Avgousti DC4, Shalhout S5, Bhagwat AS5,6, Weitzman MD2,4.
- Cell cycle (Georgetown, Tex.).Cell Cycle.2016 Apr 2;15(7):998-1008. doi: 10.1080/15384101.2016.1152426.
- The human APOBEC3 family of DNA-cytosine deaminases comprises 7 members (A3A-A3H) that act on single-stranded DNA (ssDNA). The APOBEC3 proteins function within the innate immune system by mutating DNA of viral genomes and retroelements to restrict infection and retrotransposition. Recent evidence su
- PMID 26918916
Japanese Journal
- 加藤 みゆき,大森 正司,加藤 芳伸
- 日本食品科学工学会誌 : Nippon shokuhin kagaku kogaku kaishi = Journal of the Japanese Society for Food Science and Technology 58(9), 421-427, 2011-09-15
- … 緑茶を対象としてretroposon-like sequence DNA (RLS-DNA)塩基配列の比較解析により品種の判別を試みた.実験には,やぶきた品種のチャ葉より製造した緑茶と,市販されている中国,ベトナム,ミャンマー,台湾の緑茶,そして日本の緑茶用40品種の生茶葉を用いて実験した.RLS-DNAの塩基配列を比較解析することにより,おくみどり,べにふうき等の品種の判別が生茶葉と緑茶葉を用いた場合,共に可能であることが認められ …
- NAID 10029722611
- Anatomic Modifications in the Enteric Nervous System of JF1 Mice with the Classic Piebald Mutation
- DANG Ruihua,SASAKI Nobuya,TORIOE Daisuke,AGUI Takashi
- Journal of Veterinary Medical Science advpub(0), 1110280669, 2011
- … In this study, we identified the insertion of retroposon-like element in intron 1 of the Ednrb gene in JF1 same as classic piebald mutation by PCR. …
- NAID 130001409980
Related Links
- Looking for online definition of retroposon in the Medical Dictionary? retroposon explanation free. What is retroposon? Meaning of retroposon medical term. What does retroposon mean? Retroposon | definition of retroposon by ? ...
- Retroposon definition at Dictionary.com, a free online dictionary with pronunciation, synonyms and translation. Look it up now! ... retroposon ret·ro·po·son (rět'rō-pō'sən) n. A transposition of DNA sequences that does not occur in ...
★リンクテーブル★
[★]
- 英
- retrotransposon
- 関
- retroelement、retroposon
- 転写されたRNAから逆転写でゲノムに組み込まれる自己増殖性の転移因子
[★]
- 英
- retroposon
- 関
- レトロトランスポゾン、レトロエレメント、トランスポゾン
[★]
レトロエレメント
- 関
- retroposon、retrotransposon