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English Journal
- N-Acetylcysteine and allopurinol up-regulated the Jak/STAT3 and PI3K/Akt pathways via adiponectin and attenuated myocardial postischemic injury in diabetes.
- Wang T, Mao X, Li H, Qiao S, Xu A, Wang J, Lei S, Liu Z, Ng KF, Wong GT, Vanhoutte PM, Irwin MG, Xia Z.SourceDepartment of Anesthesiology, The University of Hong Kong, Hong Kong SAR, China; Department of Anesthesiology and Critical Care, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
- Free radical biology & medicine.Free Radic Biol Med.2013 Oct;63:291-303. doi: 10.1016/j.freeradbiomed.2013.05.043. Epub 2013 Jun 6.
- N-Acetylcysteine (NAC) and allopurinol (ALP) synergistically reduce myocardial ischemia reperfusion (MI/R) injury in diabetes. However, the mechanism is unclear. We postulated that NAC and ALP attenuated diabetic MI/R injury by up-regulating phosphatidylinositol 3-kinase/Akt (PI3K/Akt) and Janus kin
- PMID 23747931
- TIFA upregulation after hypoxia-reoxygenation is TLR4- and MyD88-dependent and associated with HMGB1 upregulation and release.
- Ding N, Zhang Y, Loughran PA, Wang Q, Tsung A, Billiar TR.SourceDepartment of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA; Department of Anesthesiology, Guangzhou First People's Hospital, Guangzhou Medical University, Guangzhou 510180, China. Electronic address: dingninggz@hotmail.com.
- Free radical biology & medicine.Free Radic Biol Med.2013 Oct;63:361-7. doi: 10.1016/j.freeradbiomed.2013.05.029. Epub 2013 May 28.
- TRAF-interacting protein with a forkhead-associated domain (TIFA) is a tumor necrosis factor receptor-associated factor 6 (TRAF6) binding protein that mediates IL-1 signaling. We recently reported that TIFA mRNA is significantly upregulated early in the liver after trauma and hemorrhagic shock. In t
- PMID 23722163
Japanese Journal
- Chronic treatment with a water-soluble extract from the culture medium of Ganoderma lucidum mycelia (MAK) prevents apoptosis and necroptosis in hypoxia/ischemia-induced injury of type 2 diabetic mouse brain
- 玄 美燕,岡﨑 真理,岩田 直洋,浅野 哲,神内 伸也,松崎 広和,坂本 武史,Miyano Yoshiyuki,飯塚 博,日比野 康英
- Evidence-based complementary and alternative medicine 2015(865986), 1-29, 2015-02-03
- … H/I was induced by a combination of unilateral common carotid artery ligation with hypoxia (8% O2 for 20 min) and subsequent reoxygenation. … Pretreatment with MAK (1 g/kg, p.o.) for a week significantly reduced H/I-induced neurological deficits and brain infarction volume assessed at 24 h of reoxygenation. …
- NAID 120005590299
- 炎症・サイトカインと睡眠呼吸障害 (特集 循環器疾患と睡眠呼吸障害)
- Protective HSP70 Induction by Z-Ligustilide against Oxygen Glucose Deprivation Injury via Activation of the MAPK Pathway but Not of HSF1
- Yu Jie,Jiang Zhuyun,Ning Ling,Zhao Zhilong,Yang Na,Chen Lu,Ma Hui,Li Li,Fu Ya,Zhu Huifeng,Qi Hongyi
- Biological and Pharmaceutical Bulletin advpub(0), 2015
- … Meanwhile, Z-ligustilide enhanced the cell viability of PC12 cells insulted by oxygen glucose deprivation-reoxygenation (OGD-Reoxy) and decreased apoptotic and necrotic cell death. …
- NAID 130005089209
Related Links
- reoxygenation /re·ox·y·gen·a·tion/ (re-ok″sĭ-jen-a´shun) in radiobiology, the phenomenon in which hypoxic (and thus radioresistant) tumor cells become more exposed to oxygen (and thus more radiosensitive) by coming into closer ...
- ABSTRACT 様々の臓器における虚血後再酸素化(ischemia/reoxygenation; I/R)時の細胞や機能の傷害は,発生する種々のフリーラジカルや,過酸化脂質によると考えられている.一方,アスコルビン酸(AsA)は,低濃度では過酸化を促進し,高濃度では ...
Related Pictures
★リンクテーブル★
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- 関
- reoxygenation
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- 英
- reoxygenation、reoxygenate