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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/02/23 22:14:05」(JST)

English Journal

Stearic acid and high molecular weight PEO as matrix for the highly water soluble metoprolol tartrate in continuous twin-screw melt granulation.

Monteyne T1, Adriaensens P2, Brouckaert D3, Remon JP4, Vervaet C5, De Beer T6.
International journal of pharmaceutics.Int J Pharm.2016 Oct 15;512(1):158-67. doi: 10.1016/j.ijpharm.2016.07.035. Epub 2016 Jul 21.
Granules with release-sustaining properties were developed by twin screw hot melt granulation (HMG) using a combination of stearic acid (SA) and high molecular weight polyethylene oxide (PEO) as matrix for a highly water soluble model drug, metoprolol tartrate (MPT). Earlier studies demonstrated tha
PMID 27452420

The secondary structure and the thermal unfolding parameters of the S-layer protein from Lactobacillus salivarius.

Lighezan L1, Georgieva R2, Neagu A3.
European biophysics journal : EBJ.Eur Biophys J.2016 Sep;45(6):491-509. doi: 10.1007/s00249-016-1117-2. Epub 2016 Mar 18.
Surface layer (S-layer) proteins have been identified in the cell envelope of many organisms, such as bacteria and archaea. They self-assemble, forming monomolecular crystalline arrays. Isolated S-layer proteins are able to recrystallize into regular lattices, which proved useful in biotechnology. H
PMID 26992716

Improving the granule strength of roller-compacted ibuprofen sodium for hot-melt coating processing.

Lopes DG1, Garsuch V2, Becker K3, Paudel A4, Stehr M5, Zimmer A3, Salar-Behzadi S6.
International journal of pharmaceutics.Int J Pharm.2016 Aug 20;510(1):285-95. doi: 10.1016/j.ijpharm.2016.06.049. Epub 2016 Jun 21.
Solvent-free hot-melt coating processing is a novel and cost-efficient approach to manufacturing taste-masked multiparticulate systems. However, most API powders are fine and cohesive and not processable by hot-melt coating. The aim of this study was to produce dense and abrasion-resistant granules
PMID 27346416