WordNet
- a harmful or corrupting agency; "bigotry is a virus that must not be allowed to spread"; "the virus of jealousy is latent in everyone"
- (virology) ultramicroscopic infectious agent that replicates itself only within cells of living hosts; many are pathogenic; a piece of nucleic acid (DNA or RNA) wrapped in a thin coat of protein
- a software program capable of reproducing itself and usually capable of causing great harm to files or other programs on the same computer; "a true virus cannot spread to another computer without human assistance" (同)computer virus
- of or relating to recombinant DNA
- a cell or organism in which genetic recombination has occurred
PrepTutorEJDIC
- ビールス,ろ過性病原体
- 遺伝子の新結合による
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/07/27 13:59:14」(JST)
[Wiki en表示]
A recombinant virus is a virus produced by recombining pieces of DNA using recombinant DNA technology. This may be used to produce viral vaccines or gene therapy vectors.
It is also used to refer to naturally occurring recombination between virus genomes in a cell infected by more than one virus strain. This occurs either by homologous crossing over of the nucleic acid strands or by reassortment of genomic segments. Both these and mutation within the virus have been suggested as ways in which influenza and other viruses evolve. An example of a recombinant virus is Western equine encephalitis virus (WEE), which is a recombinant virus between two other closely related yet distinct encephalitis viruses. In addition, reassortment is most important for pandemic influenza viruses.
See also
References
- Recombination Resulting in Virulence Shift in Avian Influenza Outbreak, Chile. Suarez et al 2009
- Homologous Recombination as an Evolutionary Force in the Avian Influenza A Virus. He at al 2008
External links
- Dr. Jeffery Taubenberger on: A Recombinant Virus
- Viral Genetics
- Transmission of Influenza A Viruses Between Animals and People
Microbiology: Virus
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Components |
- Viral envelope
- Capsid
- Viral protein
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Viral life cycle |
- Viral entry
- Viral replication
- Viral shedding
- Virus latency
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Genetics |
- Reassortment
- Antigenic shift
- Antigenic drift
- Phenotype mixing
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By host |
- Bacteriophage
- Virophage
- Mycovirus
- Plant virus (Plant to Human)
- Animal virus
- Human virome
- Archea virus
- Amoeba virus
- Chromalveolata virus
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Other |
- Viral disease
- Helper virus
- Laboratory diagnosis of viral infections
- Viral load
- Virus-like particle
- Viral quantification
- Antiviral drug
- Neurotropic virus
- Oncovirus
- History of viruses
- Satellite virus
- Giant viruses
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Index of viral disease
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Description |
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Disease |
- Systemic
- Cutaneous
- Zoster
- Human papillomavirus
- Zoonotic
- Symptoms and signs
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Treatment |
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UpToDate Contents
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English Journal
- The transcription regulation analysis of Ctenopharyngodon idellus PKR and PKZ genes.
- Liu D1, Mao H1, Gu M1, Xu X1, Sun Z1, Lin G1, Wang H1, Xie D1, Hou Q1, Wang X1, Mi Y1, Liu X1, Hu C2.
- Gene.Gene.2016 Jan 15;576(1 Pt 3):512-9. doi: 10.1016/j.gene.2015.10.070. Epub 2015 Nov 4.
- Protein kinase R (PKR), the double-stranded RNA-activated protein kinase, exists in mammalian and fish. PKZ, a PKR-like protein kinase containing Z-DNA binding domains, just exists in fish. PKR and PKZ work synergistically in the antiviral defense by inhibiting intracellular protein translation. The
- PMID 26546976
- Novel interactions of domain III from the envelope glycoprotein of dengue 2 virus with human plasma proteins.
- Huerta V1, Ramos Y2, Yero A2, Pupo D2, Martín D2, Toledo P2, Fleitas N2, Gallien S3, Martín AM2, Márquez GJ2, Pérez-Riverol Y2, Sarría M2, Guirola O2, González LJ2, Domon B3, Chinea G2.
- Journal of proteomics.J Proteomics.2016 Jan 10;131:205-13. doi: 10.1016/j.jprot.2015.11.003. Epub 2015 Nov 3.
- Blood cells and plasma are important media for the four serotypes of dengue virus (DENV1-4) spreading into an infected person. Thus, interactions with human plasma proteins are expected to be decisive in the course of the viral infection. Affinity purification followed by MS analysis (AP/MS) was use
- PMID 26546555
- New broadly reactive neutralizing antibodies against hepatitis B virus surface antigen.
- Kucinskaite-Kodze I1, Pleckaityte M1, Bremer CM2, Seiz PL2, Zilnyte M1, Bulavaite A1, Mickiene G1, Zvirblis G1, Sasnauskas K1, Glebe D2, Zvirbliene A3.
- Virus research.Virus Res.2016 Jan 4;211:209-21. doi: 10.1016/j.virusres.2015.10.024. Epub 2015 Nov 2.
- Hepatitis B virus (HBV) surface antigen (HBsAg) is considered to be the most important target for the diagnosis and immune prophylaxis of HBV infection. HBsAg-specific monoclonal antibodies (MAbs) are extensively used for studying the complex structure of the HBsAg, mapping the neutralizing epitopes
- PMID 26541316
Japanese Journal
- Challenges in retinal circuit regeneration: linking neuronal connectivity to circuit function
- ,
- Biological and Pharmaceutical Bulletin advpub(0), 2015
- … Recombinant viral vectors are powerful tools not only for controlling gene expression and reprogramming cells, but also for tracing cell fates and neuronal connectivity, monitoring biological functions, and manipulating the physiological state of a specific cell population. … These virus-based approaches, combined with electrophysiology and optical imaging, will provide circuit-level insight into neural regeneration and facilitate new strategies for achieving vision restoration in the adult retina. …
- NAID 130004872295
- Challenges in Retinal Circuit Regeneration:Linking Neuronal Connectivity to Circuit Function
- ,
- Biological and Pharmaceutical Bulletin 38(3), 341-357, 2015
- … Recombinant viral vectors are powerful tools not only for controlling gene expression and reprogramming cells, but also for tracing cell fates and neuronal connectivity, monitoring biological functions, and manipulating the physiological state of a specific cell population. … These virus-based approaches, combined with electrophysiology and optical imaging, will provide circuit-level insight into neural regeneration and facilitate new strategies for achieving vision restoration in the adult retina. …
- NAID 130004872275
- Adjuvant effects of recombinant giant panda (Ailuropoda melanoleuca) IL-18 on the canine distemper disease vaccine in mice
- , , [他], , , , , , ,
- Journal of Veterinary Medical Science 77(2), 187-192, 2015
- … Canine distemper virus (CDV) is a morbillivirus known to cause morbidity and mortality in a broad range of animals. …
- NAID 130004781039
Related Links
- A recombinant virus is a virus produced by recombining pieces of DNA using recombinant DNA technology. This may be used to produce viral vaccines or gene therapy vectors. It is also used to refer to naturally occurring recombination ...
- Here is a quick overview of the recombinant SFV vector system. For a detailed protocol, click here. Before reading this, you may want to check out the normal SFV life cycle. As a reminder, here is the wild type genome: ...
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