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Autonomous assembly of epithelial structures by subrenal implantation of dissociated embryonic inner-ear cells.

Wang L1, Zhang K, Zhu HH, Gao WQ.
Neuroreport.Neuroreport.2015 May 27;26(8):473-7. doi: 10.1097/WNR.0000000000000372.
Microenvironment and cell-cell interactions play an important role during embryogenesis and are required for the stemness and differentiation of stem cells. The inner-ear sensory epithelium, containing hair cells and supporting cells, is derived from the stem cells within the otic vesicle at early e
PMID 25919994

Injectable nanoparticle-loaded hydrogel system for local delivery of sodium alendronate.

Posadowska U1, Parizek M2, Filova E3, Wlodarczyk-Biegun M4, Kamperman M5, Bacakova L6, Pamula E7.
International journal of pharmaceutics.Int J Pharm.2015 May 15;485(1-2):31-40. doi: 10.1016/j.ijpharm.2015.03.003. Epub 2015 Mar 4.
Systemic administration of bisphosphonates, e.g. sodium alendronate (Aln) is characterized by extremely low bioavailability and high toxicity. To omit aforementioned drawbacks an injectable system for the intra-bone delivery of Aln based on Aln-loaded nanoparticles (NPs-Aln) suspended in a hydrogel
PMID 25747455

Stirred suspension bioreactors as a novel method to enrich germ cells from pre-pubertal pig testis.

Dores C1, Rancourt D, Dobrinski I.
Andrology.Andrology.2015 Apr 15. doi: 10.1111/andr.12031. [Epub ahead of print]
To study spermatogonial stem cells the heterogeneous testicular cell population first needs to be enriched for undifferentiated spermatogonia, which contain the stem cell population. When working with non-rodent models, this step requires working with large numbers of cells. Available cell separatio
PMID 25877677