Radioiodination of an endotoxin·MD-2 complex generates a novel sensitive, high-affinity ligand for TLR4.
Teghanemt A1, Weiss JP, Gioannini TL.
Innate immunity.Innate Immun.2013 Oct;19(5):545-60. doi: 10.1177/1753425913475688. Epub 2013 Feb 25.
A purified complex of metabolically labeled [(3)H]lipooligosaccharide (LOS) and recombinant human myeloid differentiation factor 2 (MD-2), [(3)H]LOS·MD-2, has been used to demonstrate pM affinity binding interactions with soluble TLR4 ectodomain (TLR4ecd). For measurement of the binding parameters
Stereoselective synthesis of an iodinated resveratrol analog: preliminary bioevaluation studies of the radioiodinated species.
Dhyani MV1, Kameswaran M, Korde AG, Pandey U, Chattopadhyay S, Banerjee S.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.Appl Radiat Isot.2011 Jul;69(7):996-1001. doi: 10.1016/j.apradiso.2011.01.024. Epub 2011 Feb 2.
Stereoselective synthesis of an E-hydroxystilbene has been carried out using the McMurry reaction. Synthesis of a monoiodinated hydroxystilbene has been carried out by a McMurry cross-coupling reaction. For the purpose of biological evaluation, the facile electrophilic substitution route has been at
Radioiodination of humic substances via azocoupling with 3-[125I] iodoaniline.
Franke K1, Patt JT, Kupsch H, Warwick P.
Environmental science & technology.Environ Sci Technol.2008 Jun 1;42(11):4083-7.
A new method is described for radiolabeling humic substances (HS) with iodine radioisotopes. The method radiolabels the electron-rich aromatic moieties of HS with the 3-[125I]iodobenzenediazonium ion via azocoupling. The method uses four steps: (i) 3-aminobenzenetrimethylstannane is synthesized and
Quizzes & Games Word of the Day Video New Words My Favorites View your list of saved words. (You can log in using Facebook.) Dictionary Thesaurus Medical Concise Encyclopedia New! Spanish Central radioiodinate ra·dio·io ...