radioimmune

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1. シャーガス病：自然史と診断 chagas disease natural history and diagnosis
2. 小児におけるヒトヘルペスウイルス6感染：臨床症状、診断および治療 human herpesvirus 6 infection in children clinical manifestations diagnosis and treatment
3. シャーガス病の疫学および管理 epidemiology and control of chagas disease
4. 免疫グロブリンの機能および臨床応用 function and clinical applications of immunoglobulins
5. IgG サブクラス欠乏症 igg subclass deficiency

Molecular Imaging of Death Receptor 5 Occupancy and Saturation Kinetics In Vivo by Humanized Monoclonal Antibody CS-1008.

Burvenich IJ, Lee FT, Cartwright GA, O'Keefe GJ, Makris D, Cao D, Gong S, Chueh AC, Mariadason JM, Brechbiel MW, Beckman RA, Fujiwara K, von Roemeling R, Scott AM.SourceAuthors' Affiliations: Tumour Targeting Laboratory and Oncogenic Transcription Laboratory, Ludwig Institute for Cancer Research; Department of Nuclear Medicine and Centre for PET, Austin Health, Melbourne, Australia; Radioimmune & Inorganic Chemistry Section, Radiation Oncology Branch, Cancer Research Centre, Bethesda, Maryland; Clinical Development-Oncology, Daiichi Sankyo Pharmaceutical Development, Edison, New Jersey; and Global Project Management Department, Daiichi Sankyo Co. Ltd., Tokyo, Japan.
Clinical cancer research : an official journal of the American Association for Cancer Research.Clin Cancer Res.2013 Nov 1;19(21):5984-93. doi: 10.1158/1078-0432.CCR-12-3104. Epub 2013 Sep 17.
PURPOSE: CS-1008 (tigatuzumab; phase I/II), an antihuman death receptor 5 (DR5) agonist, induces apoptosis and has cytotoxic activity against human cancer cell lines. This study reports on the preclinical validation of (111)In-labeled anti-DR5 humanized antibody CS-1008 as a diagnostic tool to study
PMID 24045184

Kanatsuna N, Taneera J, Vaziri-Sani F, Wierup N, Larsson HE, Delli A, Skärstrand H, Balhuizen A, Bennet H, Steiner DF, Törn C, Fex M, Lernmark Å.SourceFrom the Department of Clinical Sciences, Lund University Diabetes Center, Lund University, Skåne University Hospital SUS, SE-205 02 Malmö, Sweden and.
The Journal of biological chemistry.J Biol Chem.2013 Oct 4;288(40):29013-23. doi: 10.1074/jbc.M113.478222. Epub 2013 Aug 9.
Insulin is a major autoantigen in islet autoimmunity and progression to type 1 diabetes. It has been suggested that the insulin B-chain may be critical to insulin autoimmunity in type 1 diabetes. INS-IGF2 consists of the preproinsulin signal peptide, the insulin B-chain, and eight amino acids of the
PMID 23935095

Mapping biological behaviors by application of longer-lived positron emitting radionuclides.

Zhou Y, Baidoo KE, Brechbiel MW.SourceRadioimmune & Inorganic Chemistry Section, ROB, NCI, NIH, Bethesda, MD 20892-1002, USA.
Advanced drug delivery reviews.Adv Drug Deliv Rev.2013 Jul;65(8):1098-111. doi: 10.1016/j.addr.2012.10.012. Epub 2012 Nov 2.
With the technological development of positron emission tomography (PET) and the advent of novel antibody-directed drug delivery systems, longer-lived positron-emitting radionuclides are moving to the forefront to take important roles in tracking the distribution of biotherapeutics such as antibodie
PMID 23123291

梅澤慎一,金森晃,藤井英,田中啓司,平井法博,矢島義忠
北里医学 25(6), 491-497, 1995-12-31
間接凝集法(PHA法)によるサイロイドテスト(TGHA)やマイクロゾームテスト(MCHA)に代わって,最近,ラジオイムノアッセイ(RIA法)により,TGHAはTgAb,MCHAはTPOAbとして定量的測定が可能となったため,自己免疫性甲状腺疾患における陽性率をPHA法と比較検討した。TgAbはTGHAと,TPOAbはMCHAと共に有意な正の相関が認められた(r=0.895,r=0.907,p&lt …
NAID 110004696846

MATSUOKA Yasuhiro,IDOTA Tadashi
Journal of Nutritional Science and Vitaminology 41(2), 241-251, 1995
The concentration of epidermal growth factor (EGF) in human milk was measured by radioreceptor assay (RRA). Human milk samples collected from healthy Japanese mothers who delivered at full term were d …
NAID 130001369997