English Journal

Targeted localized use of therapeutic antibodies: a review of non-systemic, topical and oral applications.

Jones RG1, Martino A1.
Critical reviews in biotechnology.Crit Rev Biotechnol.2016 Jun;36(3):506-20. doi: 10.3109/07388551.2014.992388. Epub 2015 Jan 20.
Therapeutic antibodies provide important tools in the "medicine chest" of today's clinician for the treatment of a range of disorders. Typically monoclonal or polyclonal antibodies are administered in large doses, either directly or indirectly into the circulation, via a systemic route which is well
PMID 25600465

Anti-inflammatory panacea? The expanding therapeutics of interleukin-1 blockade.

Kahlenberg JM1.
Current opinion in rheumatology.Curr Opin Rheumatol.2016 May;28(3):197-203. doi: 10.1097/BOR.0000000000000266.
PURPOSE OF REVIEW: Blockade of interleukin (IL)-1 signaling is one of the oldest biologic therapies, yet the use of these agents is on the rise as the role of IL-1 activation is being recognized in a wide spectrum of inflammatory disorders. This review will cover established and emerging uses of IL-
PMID 26859478

Treatment of Pyoderma Gangrenosum - Retrospective Multicenter Analysis of 121 Patients.

Herberger K1, Dissemond J2, Hohaus K2, Schaller J3, Anastasiadou Z1, Augustin M1.
The British journal of dermatology.Br J Dermatol.2016 Apr 5. doi: 10.1111/bjd.14619. [Epub ahead of print]
Therapeutic strategy of pyoderma gangrenosum (PG) includes suppression of inflammatory disease activity, treatment of associated morbidities, promotion of wound healing and pain relief.1 However, treatment remains challenging due to the lack of approved therapies and difficulty measuring response. O
PMID 27060666

Japanese Journal

臀部慢性膿皮症から生じた有棘細胞癌の1例

川﨑雅人,黒川正人,日下淳子,瀧本浩樹,桂良輔,西尾祐美,塚本吉胤
Skin Cancer 29(1), 24-28, 2014
56歳，男性。約20年前より両側臀部膿皮症を認め，寛解と増悪を繰り返していた。右臀部中央にカリフラワー様腫瘤を認めたため，生検を行った結果，有棘細胞癌であった。全身検索で遠隔転移は認めなかった。手術で右鼠径部のセンチネルリンパ節生検，膿皮症および有棘細胞癌の切除を行い，皮膚欠損部には人工真皮を貼付した。病理組織の結果，リンパ節転移はなく，病期分類はpT3N0M0 Stage IIIと診断した。永久 …
NAID 130004688960

痔瘻を合併し巨大な腫瘤を形成した臀部慢性膿皮症の1例 (特集細菌・抗酸菌・スピロヘータ感染症)

横瀬千美,磯久太郎,飯田沙織 [他]
皮膚科の臨床 55(11), 1363-1366, 2013-11
NAID 40019872900

膿瘍天蓋除去により治療した頭部慢性膿皮症

金子栄,三原祐子,高塚純子 [他]
皮膚科の臨床 54(8), 1081-1085, 2012-08
NAID 40019404463

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Pickel an den Wangen | Tipps auf Pickel Gangrenøs pyodermia Moulage, Pyodermia chronica (Handgelenk вегетирующая (pyodermia пиодермия, pyodermia Pyodermia vegetans - P. Altmeyer Рис. 1 и 2. Ulerythema sycosiforme Pyodermia bullosum (stafylokokki)