- 関
- chromatic agglutination、karyopyknosis、pyknosis
WordNet
- of or relating to or exhibiting pyknosis (同)pycnotic
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2017/08/16 20:02:53」(JST)
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Morphological characteristics of pyknosis and other forms of nuclear destruction
Pyknosis, or karyopyknosis, is the irreversible condensation of chromatin in the nucleus of a cell undergoing necrosis[1] or apoptosis.[2] It is followed by karyorrhexis, or fragmentation of the nucleus. Pyknosis (from Greek pyknono meaning "to thicken up, to close or to condense") is also observed in the maturation of erythrocytes (a red blood cell) and the neutrophil (a type of white blood cell). The maturing metarubricyte (a stage in RBC maturation) will condense its nucleus before expelling it to become a reticulocyte. The maturing neutrophil will condense its nucleus into several connected lobes that stay in the cell until the end of its cell life.
Pyknotic nuclei are often found in the zona reticularis of the adrenal gland. They are also found in the keratinocytes of the outermost layer in parakeratinised epithelium.
See also
References
- ^ Kumar V, Abbas A, Nelson F, Mitchell R (2007). "Robbins Basic Pathology". Robbins Basic Pathology (8th ed.): 6, 9–10 (table 1–1).
- ^ Kroemer G, Galluzzi L, Vandenabeele P, et al. (January 2009). "Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009". Cell Death Differ. 16 (1): 3–11. PMC 2744427 . PMID 18846107. doi:10.1038/cdd.2008.150.
Pathology
|
Principles of pathology |
- Disease
- Infection
- Neoplasia
- Cause
- Pathogenesis
- Hemodynamics
- Inflammation
- Cell damage
- Wound healing
- Cellular adaptation
- Atrophy
- Hypertrophy
- Hyperplasia
- Dysplasia
- Metaplasia
- Squamous
- Glandular
- Cell death
- Necrosis
- Coagulative necrosis
- Liquefactive necrosis
- Gangrenous necrosis
- Caseous necrosis
- Fat necrosis
- Fibrinoid necrosis
- Programmed cell death
- Apoptosis
- Pyknosis
- Karyorrhexis
- Karyolysis
- Accumulations
- pigment
- Hemosiderin
- Lipochrome/Lipofuscin
- Melanin
- Steatosis
|
Anatomical pathology |
- Surgical pathology
- Cytopathology
- Autopsy
- Molecular pathology
- Forensic pathology
- Oral and maxillofacial pathology
- Gross examination
- Histopathology
- Immunohistochemistry
- Electron microscopy
- Immunofluorescence
- Fluorescence in situ hybridization
|
Clinical pathology |
- Clinical chemistry
- Hematopathology
- Transfusion medicine
- Medical microbiology
- Diagnostic immunology
- Immunopathology
- Enzyme assay
- Mass spectrometry
- Chromatography
- Flow cytometry
- Blood bank
- Microbiological culture
- Serology
|
UpToDate Contents
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English Journal
- Exposure to E2 and EE2 environmental concentrations affect different components of the Brain-Pituitary-Gonadal axis in pejerrey fish (Odontesthes bonariensis).
- Gárriz Á1, Del Fresno PS1, Miranda LA2.
- Ecotoxicology and environmental safety.Ecotoxicol Environ Saf.2017 Oct;144:45-53. doi: 10.1016/j.ecoenv.2017.06.002. Epub 2017 Jun 8.
- PMID 28601516
- Antimicrobial agents, triclosan, chloroxylenol, methylisothiazolinone and borax, used in cleaning had genotoxic and histopathologic effects on rainbow trout.
- Capkin E1, Ozcelep T2, Kayis S3, Altinok I4.
- Chemosphere.Chemosphere.2017 Sep;182:720-729. doi: 10.1016/j.chemosphere.2017.05.093. Epub 2017 May 15.
- PMID 28531838
- N-nitrosamines induced infertility and hepatotoxicity in male rabbits.
- Sheweita SA1, El Banna YY1, Balbaa M2, Abdullah IA1, Hassan HE1.
- Environmental toxicology.Environ Toxicol.2017 Sep;32(9):2212-2220. doi: 10.1002/tox.22436. Epub 2017 Jun 2.
- PMID 28573719
Japanese Journal
- N,N'-Bis(2-chloroethyl)-N-nitrosourea (BCNU)-induced Apoptosis of Neural Progenitor Cells in the Developing Fetal Rat Brain
- YAMAGUCHI Tsuyoshi,KANEMITSU Hiroyuki,YAMAMOTO Satoshi,KOMATSU Masahiko,UEMURA Hiroyuki,TAMURA Kazutoshi,SHIRAI Tomoyuki
- Journal of toxicologic pathology 23(1), 25-30, 2010-03-01
- … The number of pyknotic cells in the telencephalon peaked at 24 h and then gradually decreased until 72 h. … The majority of these pyknotic cells were positive for cleaved caspase-3, a key executioner of apoptosis. … The pyknotic cells showed the ultrastructural characteristics of apoptosis. …
- NAID 10030978555
- Distribution and Sequence of Pyknotic Cells in Rat Fetuses Exposed to Busulfan
- OHIRA Toko,ANDO Ryo,ANDOH Rie,NAKAZAWA Tomomi,NISHIHARA Kaori,YAMAMOTO Satoshi,NAKAMURA Norihiko,TAMURA Kazutoshi
- Journal of toxicologic pathology 22(3), 167-171, 2009-09-01
- NAID 10030978100
- Distribution and Sequence of Pyknotic Cells in Rat Fetuses Exposed to Busulfan
- Ohira Toko,Ando Ryo,Andoh Rie,Nakazawa Tomomi,Nishihara Kaori,Yamamoto Satoshi,Nakamura Norihiko,Tamura Kazutoshi
- Journal of Toxicologic Pathology 22(3), 167-172, 2009
- … In the present study, we examined the distribution and sequence of pyknotic cells in rat fetal tissues exposed to busulfan. … Most of the pyknotic cells were considered to be apoptotic cells judging from the results of TUNEL staining and electron microscopic examination. …
- NAID 130000137717
Related Links
- The nuclei are small, pyknotic, and dark blue, and the cytoplasm is large and light blue (figure 1).
- Definition of Pyknotic with photos and pictures, translations, sample usage, and additional links for more information.
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- pyknosis、karyopyknosis、chromatic agglutination、pyknotic
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