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Simulation of particle diversity and mixing state over Greater Paris: a model-measurement inter-comparison.

Zhu S1, Sartelet KN1, Healy RM2, Wenger JC3.
Faraday discussions.Faraday Discuss.2016 Apr 25. [Epub ahead of print]
Air quality models are used to simulate and forecast pollutant concentrations, from continental scales to regional and urban scales. These models usually assume that particles are internally mixed, i.e. particles of the same size have the same chemical composition, which may vary in space and time.
PMID 27108651

Preparation of multiparticulate systems for oral delivery of a micronized or nanosized poorly soluble drug.

Cerea M1,2, Pattarino F3, Foglio Bonda A3, Palugan L1, Segale L3, Vecchio C2.
Drug development and industrial pharmacy.Drug Dev Ind Pharm.2016 Feb 18:1-10. [Epub ahead of print]
The purpose of the present work was to prepare multiparticulate drug delivery systems for oral administration of a poorly soluble drug such as itraconazole. Multiparticulate systems were prepared by extrusion/spheronization technique using a mix of crospovidone, low viscosity hypromellose, microcrys
PMID 26786555

Nanonized itraconazole powders for extemporary oral suspensions: Role of formulation components studied by a mixture design.

Foglio Bonda A1, Rinaldi M1, Segale L1, Palugan L2, Cerea M2, Vecchio C3, Pattarino F4.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.Eur J Pharm Sci.2016 Feb 15;83:175-83. doi: 10.1016/j.ejps.2015.12.030. Epub 2015 Dec 30.
Itraconazole (ITZ) nanocrystal-containing powders were prepared through the combined use of high pressure homogenization (HPH) and spray drying (SD). These powders were intended as base materials for the preparation of extemporary oral suspensions of the drug. The role and the effect of stabilizers
PMID 26742430