English Journal

Short- and medium-chain fatty acids in the energy metabolism - the cellular perspective.

Schoenfeld P1, Wojtczak L2.
Journal of lipid research.J Lipid Res.2016 Apr 14. pii: jlr.R067629. [Epub ahead of print]
Short- and medium-chain fatty acids (SCFAs and MCFAs), independently of their cellular signalling functions, are important substrates of the energy metabolism and anabolic processes in mammals. SCFAs are mostly generated by colonic bacteria and are predominantly metabolized by enterocytes and liver,
PMID 27080715

Assessment of phenolic herbicide toxicity and mode of action by different assays.

Bettiol C1, De Vettori S1, Minervini G2, Zuccon E1, Marchetto D3, Ghirardini AV4, Argese E5.
Environmental science and pollution research international.Environ Sci Pollut Res Int.2016 Apr;23(8):7398-408. doi: 10.1007/s11356-015-5958-5. Epub 2015 Dec 23.
A phytotoxicity assay based on seed germination/root elongation has been optimized and used to evaluate the toxic effects of some phenolic herbicides. The method has been improved by investigating the influence of experimental conditions. Lepidium sativum was chosen as the most suitable species, sho
PMID 26695414

Brain Lipotoxicity of Phytanic Acid and Very Long-chain Fatty Acids. Harmful Cellular/Mitochondrial Activities in Refsum Disease and X-Linked Adrenoleukodystrophy.

Schönfeld P1, Reiser G2.
Aging and disease.Aging Dis.2016 Mar 15;7(2):136-49. doi: 10.14336/AD.2015.0823. eCollection 2016.
It is increasingly understood that in the aging brain, especially in the case of patients suffering from neurodegenerative diseases, some fatty acids at pathologically high concentrations exert detrimental activities. To study such activities, we here analyze genetic diseases, which are due to compr
PMID 27114847

Japanese Journal

S-15176 and its methylated derivative suppress the CsA-insensitive mitochondrial permeability transition and subsequent cytochrome c release induced by silver ion, and show weak protonophoric activity