WordNet

an adrenergic drug used in many preparations to relieve allergic reactions or respiratory infections; "drugs containing phenylpropanolamine are being recalled"

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2012/07/06 01:11:38」(JST)

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English Journal

A randomized, controlled trial of oral propranolol in infantile hemangioma.

Léauté-Labrèze C1, Hoeger P, Mazereeuw-Hautier J, Guibaud L, Baselga E, Posiunas G, Phillips RJ, Caceres H, Lopez Gutierrez JC, Ballona R, Friedlander SF, Powell J, Perek D, Metz B, Barbarot S, Maruani A, Szalai ZZ, Krol A, Boccara O, Foelster-Holst R, Febrer Bosch MI, Su J, Buckova H, Torrelo A, Cambazard F, Grantzow R, Wargon O, Wyrzykowski D, Roessler J, Bernabeu-Wittel J, Valencia AM, Przewratil P, Glick S, Pope E, Birchall N, Benjamin L, Mancini AJ, Vabres P, Souteyrand P, Frieden IJ, Berul CI, Mehta CR, Prey S, Boralevi F, Morgan CC, Heritier S, Delarue A, Voisard JJ.
The New England journal of medicine.N Engl J Med.2015 Feb 19;372(8):735-46. doi: 10.1056/NEJMoa1404710.
BACKGROUND: Oral propranolol has been used to treat complicated infantile hemangiomas, although data from randomized, controlled trials to inform its use are limited.METHODS: We performed a multicenter, randomized, double-blind, adaptive, phase 2-3 trial assessing the efficacy and safety of a pediat
PMID 25693013

The utility of intra-operative three-dimensional transoesophageal echocardiography for dynamic measurement of stroke volume.

Suehiro K1, Tanaka K, Yamada T, Matsuura T, Funao T, Mori T, Nishikawa K.
Anaesthesia.Anaesthesia.2015 Feb;70(2):150-9. doi: 10.1111/anae.12857. Epub 2014 Sep 29.
Measurement of left ventricular stroke volume and cardiac output is very important for managing haemodynamically unstable or critically ill patients. The aims of this study were to compare stroke volume measured by three-dimensional transoesophageal echocardiography with stroke volume measured using
PMID 25265890

Reply to letter: "propranolol: a novel antihemangioma agent with multiple potential mechanisms of action".

Chim H1.
Annals of surgery.Ann Surg.2015 Feb;261(2):e53. doi: 10.1097/SLA.0000000000000453.
PMID 24374536

Japanese Journal

カリウムチャンネル遮断剤の分子設計と開発

海宝龍夫,宮本充彦,昇忠仁 [他],片上功
有機合成化学協会誌 62(1), 27-37, 2004-01-01
… Since MS-3579 lacks potency as a class III agent and its (aryloxy) propanolamine moiety was thought to be the typical β-blocking pharmacophore, we decided to manipulate this moiety to diminish β-blocking activity and potentiate class III activity. …
NAID 10011952251

Synthesis and Anticonvulsant Activity of Novel 1-Substituted-1,2-dihydro-pyridazine-3,6-diones(Medicinal Chemistry)

Sivakumar Ramaiah,Anbalagan Navaneetharaman,Gunasekaran Vedachalam [他],LEONARD Joseph Thomas
Biological & pharmaceutical bulletin 26(10), 1407-1411, 2003-10-01
The synthesis and pharmacological evaluation of novel 1-substituted-l,2-dihydro-pyridazine-3,6-diones (4a-I, 5a-j) as potential anticonvulsant agents are described. The compounds were tested in vivo f …
NAID 110003608315

Total Syntheses of Spidamine and Joramine, Polyamine Toxins from the Joro Spider, Nephila clavata

CHIBA Tadashige,AKIZAWA Toshifumi,MATSUKAWA Motomi,NISHI Masatoshi,KAWAI Nobufumi,YOSHIOKA Masanori
Chemical & pharmaceutical bulletin 44(5), 972-979, 1996-05-15
… A synthon of the common side chain was synthesized by starting with n-propanolamine which was converted to 7-azido-N-benzyloxycarbonyl-4-azaheptanoic acid N-hydroxysuccinimidyl ester. … The protected spidamine was catalytically hydrogenated to remove protective groups, affording spidamine itself in 13% yield from n-propanolamine. …
NAID 110003632004

Related Pictures

is the step of preparing a propanolamine Propanolamines (aminopropanols) Caffeine cas. No. 58-08-2, manufacturer propanolamine phenyl propanolamine bp usp Propanolamine Hydrochloride CAS number 154 File:Pindolol.png - Wikimedia Commons