propagermanium

プロパゲルマニウム

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/10/10 18:48:21」(JST)

wiki en

[Wiki en表示]

Propagermanium
IUPAC name 3-[(2-Carboxyethyl-oxogermyl)oxy-oxogermyl]propanoic acid
Other names proxigermanium, Ge-132, germanium sesquioxide, 2-carboxyethylgermasesquioxane, SK-818, bis(2-carboxyethylgermanium) sesquioxide
Identifiers
CAS number	12758-40-6
PubChem	83030
Jmol-3D images	Image 1
SMILES C(C[Ge](=O)O[Ge](=O)CCC(=O)O)C(=O)O
Properties
Molecular formula	C6H10O7Ge2
Molar mass	339.4222 g/mol
Y (verify) (what is: Y/N?) Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Propagermanium (INN), also known by a variety of other names including bis(2-carboxyethylgermanium) sesquioxide and 2-carboxyethylgermasesquioxane, is an organometallic compound of germanium that is sold as a complementary medicine. It is a polymeric compound with the formula ((HOOCCH₂CH₂Ge)₂O₃)_n.

References

English Journal

• Inhibition of MCP-1/CCR2 signaling pathway is involved in synergistic inhibitory effects of irbesartan with rosuvastatin on vascular remodeling.

• Ohshima K, Mogi M, Nakaoka H, Jing F, Iwanami J, Min LJ, Tsukuda K, Kanno H, Ogimoto A, Higaki J, Horiuchi M.SourceDepartment of Molecular Cardiovascular Biology and Pharmacology, Ehime University, Graduate School of Medicine, Tohon, Ehime, Japan.
• Journal of the American Society of Hypertension : JASH.J Am Soc Hypertens.2012 Nov-Dec;6(6):375-84. doi: 10.1016/j.jash.2012.10.002. Epub 2012 Oct 26.
• Additional beneficial effects of angiotensin II type 1 (AT(1)) receptor blockers beyond AT(1) receptor blockade have been highlighted. Irbesartan is reported to act as an antagonist of the monocyte chemoattractant protein-1 (MCP-1) receptor, C-C chemokine receptor 2 (CCR2). We examined the possible
• PMID 23107893

• Macrophages prevent hemorrhagic infarct transformation in murine stroke models.

• Gliem M, Mausberg AK, Lee JI, Simiantonakis I, van Rooijen N, Hartung HP, Jander S.SourceDepartments of Neurology, Heinrich Heine University, Medical Faculty, Moorenstrasse 5, Düsseldorf, Germany.
• Annals of neurology.Ann Neurol.2012 Jun;71(6):743-52. doi: 10.1002/ana.23529.
• OBJECTIVE: Inflammation is increasingly viewed as a new therapeutic target in subacute stages of brain infarction. However, apart from causing secondary damage, inflammation could equally promote beneficial lesion remodeling and repair. Distinct subpopulations of monocytes/macrophages (MOs/MPs) may
• PMID 22718543

• Effects of a lactobacilli, oligosaccharide and organic germanium intake on the immune responses of mice.

• Nakamura T, Saito M, Aso H.SourceAsai Germanium Research Institute Co, Ltd, Hakodate, Hokkaido, Japan. nakamura@asai-ge.co.jp
• Bioscience, biotechnology, and biochemistry.Biosci Biotechnol Biochem.2012;76(2):375-7. Epub 2012 Feb 7.
• The organic germanium compound, Ge-132, has immune-modulating effects. We evaluated the symbiotic effects of Ge-132 with lactobacilli and oligosaccharide (LB/OS) on the immune responses of mice. The highest fecal IgA levels were observed in the mice receiving a low concentration of Ge-132 with LB/OS
• PMID 22313762

Japanese Journal

• C-C Chemokine Receptor 2 Inhibitor Improves Diet-Induced Development of Insulin Resistance and Hepatic Steatosis in Mice

• Journal of Atherosclerosis and Thrombosis 17(3), 219-228, 2010
• NAID 130004444414

• Propagermanium : a nonspecific immune modulator for chronic hepatitis B

• Journal of gastroenterology 38(6), 525-532, 2003-06-01
• NAID 10012738259

• Propagermanium, a Specific Inhibitor of CCR2 Chemokine Receptor, Suppresses In-Stent Restenosis in Atherosclerotic Porcine Coronary Arteries

• Circulation journal : official journal of the Japanese Circulation Society 67(Supplement_I), 206, 2003-03-01
• NAID 110002709261

Related Links

• Propagermanium - Wikipedia, the free encyclopedia

Propagermanium. IUPAC name. 3-[(2-Carboxyethyl-oxogermyl)oxy-oxogermyl] propanoic acid. Other names. proxigermanium, Ge-132, germanium sesquioxide, 2-carboxyethylgermasesquioxane, SK-818, bis(2-carboxyethylgermanium) ...

• Propagermanium / Dietary approaches / CAM-Cancer

10 Jan 2013 ... Propagermanium is an organic germanium compound. Germanium compounds are popular as nutritional supplements and proponents advertise beneficial effects on the course of a multiplicity of illnesses. Propagermanium ...

Related Pictures

---

★リンクテーブル★

リンク元	「プロパゲルマニウム」

「プロパゲルマニウム」

　　[★]

英

propagermanium

商

セロシオン、セロシオンカプセル

関

肝臓疾患用剤、ゲルマニウム