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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/10/10 18:48:21」(JST)

English Journal

Inhibition of MCP-1/CCR2 signaling pathway is involved in synergistic inhibitory effects of irbesartan with rosuvastatin on vascular remodeling.

Ohshima K, Mogi M, Nakaoka H, Jing F, Iwanami J, Min LJ, Tsukuda K, Kanno H, Ogimoto A, Higaki J, Horiuchi M.SourceDepartment of Molecular Cardiovascular Biology and Pharmacology, Ehime University, Graduate School of Medicine, Tohon, Ehime, Japan.
Journal of the American Society of Hypertension : JASH.J Am Soc Hypertens.2012 Nov-Dec;6(6):375-84. doi: 10.1016/j.jash.2012.10.002. Epub 2012 Oct 26.
Additional beneficial effects of angiotensin II type 1 (AT(1)) receptor blockers beyond AT(1) receptor blockade have been highlighted. Irbesartan is reported to act as an antagonist of the monocyte chemoattractant protein-1 (MCP-1) receptor, C-C chemokine receptor 2 (CCR2). We examined the possible
PMID 23107893

Gliem M, Mausberg AK, Lee JI, Simiantonakis I, van Rooijen N, Hartung HP, Jander S.SourceDepartments of Neurology, Heinrich Heine University, Medical Faculty, Moorenstrasse 5, Düsseldorf, Germany.
Annals of neurology.Ann Neurol.2012 Jun;71(6):743-52. doi: 10.1002/ana.23529.
OBJECTIVE: Inflammation is increasingly viewed as a new therapeutic target in subacute stages of brain infarction. However, apart from causing secondary damage, inflammation could equally promote beneficial lesion remodeling and repair. Distinct subpopulations of monocytes/macrophages (MOs/MPs) may
PMID 22718543

Effects of a lactobacilli, oligosaccharide and organic germanium intake on the immune responses of mice.

Nakamura T, Saito M, Aso H.SourceAsai Germanium Research Institute Co, Ltd, Hakodate, Hokkaido, Japan. nakamura@asai-ge.co.jp
Bioscience, biotechnology, and biochemistry.Biosci Biotechnol Biochem.2012;76(2):375-7. Epub 2012 Feb 7.
The organic germanium compound, Ge-132, has immune-modulating effects. We evaluated the symbiotic effects of Ge-132 with lactobacilli and oligosaccharide (LB/OS) on the immune responses of mice. The highest fecal IgA levels were observed in the mice receiving a low concentration of Ge-132 with LB/OS
PMID 22313762

C-C Chemokine Receptor 2 Inhibitor Improves Diet-Induced Development of Insulin Resistance and Hepatic Steatosis in Mice

Propagermanium, a Specific Inhibitor of CCR2 Chemokine Receptor, Suppresses In-Stent Restenosis in Atherosclerotic Porcine Coronary Arteries

Circulation journal : official journal of the Japanese Circulation Society 67(Supplement_I), 206, 2003-03-01
NAID 110002709261

リンク元	「プロパゲルマニウム」

Propagermanium
	IUPAC name 3-[(2-Carboxyethyl-oxogermyl)oxy-oxogermyl]propanoic acid
	Other names proxigermanium, Ge-132, germanium sesquioxide, 2-carboxyethylgermasesquioxane, SK-818, bis(2-carboxyethylgermanium) sesquioxide
Identifiers
CAS number	12758-40-6
PubChem	83030
Jmol-3D images	Image 1
	SMILES C(C[Ge](=O)O[Ge](=O)CCC(=O)O)C(=O)O ;
Properties
Molecular formula	C6H10O7Ge2
Molar mass	339.4222 g/mol
	(verify) (what is: /?); Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
	Infobox references