UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

1. クロストリジウム性筋肉壊死clostridial myonecrosis [show details]
…(clostridial gas gangrene) consists of progressive invasion and destruction of healthy muscle tissue. Traumatic gas gangrene is most commonly caused by C. perfringens; spontaneous gangrene is most commonly …
2. 壊死性軟部組織感染症necrotizing soft tissue infections [show details]
…polymicrobial (type I) infection include synergistic necrotizing cellulitis and progressive bacterial synergistic gangrene. Monomicrobial (type II) necrotizing infection is usually caused by GAS or other …
3. 成人における結節性多発動脈炎の臨床症状および診断clinical manifestations and diagnosis of polyarteritis nodosa in adults [show details]
… Progressive skin involvement may be severe, including infarction and gangrene of the fingers,… erythematosus, rheumatoid arthritis, systemic sclerosis), infectious diseases (eg, chronic viral hepatitis, bacterial endocarditis), embolic disorders (eg, atherosclerosis and recent arterial catheterization), or thrombotic…
4. HIV非感染の免疫不全患者における発熱および発疹fever and rash in immunocompromised patients without hiv infection [show details]
… gas gangrene). The latter two entities are often associated with a rapidly progressive and fatal outcome .… dysfunction, particularly primary immunoglobulin and complement deficiencies, are at risk for certain bacterial, viral, and parasitic infections, particularly infections with encapsulated bacteria such as Streptococcus …
5. 創傷マネージメントの基本原則basic principles of wound management [show details]
… prevent bacterial overgrowth, ensure proper fluid balance, be cost-efficient, and be manageable for the patient and/or nursing staff. Wounds that demonstrate progressive healing as… warrant antibiotic therapy include local (cellulitis, lymphangitic streaking, purulence, malodor, wet gangrene, osteomyelitis, etc.) and systemic (fever, chills, nausea, hypotension, hyperglycemia, leukocytosis …

English Journal

Aggressive Soft Tissue Infections.

Garcia NM, Cai J.
The Surgical clinics of North America. 2018 Oct;98(5)1097-1108.
Necrotizing soft tissue infections (NSTI) are characterized by rapidly progressive infection that causes tissue necrosis with associated sepsis and multisystem organ failure. A rapid diagnosis is essential to decreasing the morbidity and mortality of NSTIs. There must be a high index of suspicion ba
PMID 30243450

An unusual case of noma caused by Klebsiella pnuemoniae and its management.

Gupta A, Sardana K, Gautam RK.
Tropical doctor. 2018 Jul;48(3)230-232.
Noma or cancrum oris is an orofacial gangrene causing progressive mutilating destruction of the infected tissues. It mainly affects malnourished children with poor oral hygiene and concurrent debilitating systemic illnesses. It is a polymicrobial infection and borrelia vincentii and fusobacterium ar
PMID 29368993

Fournier's Gangrene Does Not Spare Young Adults.

Semenič D, Kolar P.
Wounds : a compendium of clinical research and practice. 2018 Jul;30(7)E73-E76.
Fournier's gangrene is a rare but severe form of necrotizing fasciitis, primarily affecting the perianal, genital, and perineal regions. It is a rapidly progressive disease and can be potentially fatal; therefore, it should be treated as an emergency. Presented herein is the case of a 30-year-old ma
PMID 30059341

Japanese Journal

食道癌分割手術経過中食道瘻周囲皮膚に発症した壊死性軟部組織感染症の1例

満枝怜子,田原正宏,徳永裕貴,大田修平,藤家雅志,藤田博正
日本臨床外科学会雑誌 78(7), 1517-1523, 2017
食道癌術後に連鎖球菌と黄色ブドウ球菌の混合感染による皮膚の壊死性軟部組織感染症を発症した症例を報告した．デブリドマンと強力な抗菌薬が奏効した．症例は80歳の男性，術前の上気道細菌検査で連鎖球菌，黄色ブドウ球菌などの保菌が確認された．第一期手術として右開胸開腹食道亜全摘・胸壁前胃管挙上，頸部食道瘻，胃瘻造設術を行った．術後1週に食道瘻周囲に軽度の炎症を認めた．術後5週には食道瘻周囲皮膚が壊死に陥り， …
NAID 130006329533

無カタラーゼ症に就て

吉屋勝
口腔病学会雑誌 19(1), 18-25, 1952
… They have suffered mildly or severely from a paticular gangrenous inflammation over the oral region caused by bacterial infections, at the beginning of the disturbance, closely resembling alveolar pyorrhoea, but much more malignous. … The disease has tendency more or less to a progressive gangrenous condition unless the infected teeth are extracted. …
NAID 130004280875