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English Journal

Autocrine Secretion of Progastrin Promotes the Survival and Self-Renewal of Colon Cancer Stem-like Cells.

Giraud J1, Failla LM2, Pascussi JM1, Lagerqvist EL1, Ollier J1, Finetti P3, Bertucci F3, Ya C1, Gasmi I1, Bourgaux JF4, Prudhomme M4, Mazard T5, Ait-Arsa I5, Houhou L6, Birnbaum D3, Pélegrin A5, Vincent C5, Ryall JG7, Joubert D1, Pannequin J8, Hollande F9.
Cancer research.Cancer Res.2016 Jun 15;76(12):3618-28. doi: 10.1158/0008-5472.CAN-15-1497. Epub 2016 May 4.
Subpopulations of cancer stem-like cells (CSC) are thought to drive tumor progression and posttreatment recurrence in multiple solid tumors. However, the mechanisms that maintain stable proportions of self-renewing CSC within heterogeneous tumors under homeostatic conditions remain poorly understood
PMID 27197176

New ARCHITECT plasma pro-gastrin-releasing peptide assay for diagnosing and monitoring small-cell lung cancer.

Nisman B1, Nechushtan H1, Biran H2, Peled N2, Gantz-Sorotsky H1, Doviner V3, Perelman M4, Bar J2, Onn A2, Uziely B1, Peretz T1.
British journal of cancer.Br J Cancer.2016 Feb 16;114(4):469-76. doi: 10.1038/bjc.2016.7. Epub 2016 Jan 26.
BACKGROUND: Progastrin-releasing peptide (ProGRP) is a potential marker for small-cell lung cancer (SCLC) in serum; however, it may be more stable in plasma. We investigated a new plasma assay (ProGRPp) and its usefulness in diagnosing and monitoring SCLC.METHODS: The marker concentrations were dete
PMID 26812573

Role of a serum-based biomarker panel in the early diagnosis of lung cancer for a cohort of high-risk patients.

Yang DW1,2, Zhang Y1,2, Hong QY1,2, Hu J1,2, Li C1,2, Pan BS3, Wang Q4, Ding FH1, Ou JX1, Liu FL1, Zhang D1, Zhou JB1, Song YL1,2, Bai CX1,2,5.
Cancer.Cancer.2015 Sep 1;121 Suppl 17:3113-21. doi: 10.1002/cncr.29551.
BACKGROUND: This study applied a combined cancer biomarker panel to clinically identify small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC) in a high-risk population.METHODS: The serum levels of 4 biomarkers (progastrin-releasing peptide [ProGRP], carcinoembryonic antigen [CEA], squ
PMID 26331818

Long-term Survival of a Patient with Typical Lung Carcinoid Tumor and Supraclavicular Lymph Node Metastasis Treated by Surgical Resection

頭頸部がん用の2種類の熱可塑性マスクにおけるCone-beam CTを用いたinter/intrafraction setup errorの評価, Velec M, Waldron JN, O'Sullivan B et al., Int. J. Radiation Oncology Biol. Phys., 2010;76(3):949-955(世界の論文シリーズ)