WordNet

an early symptom that a disease is developing or that an attack is about to occur (同)prodroma

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1. ハンチントン病：臨床的特徴および診断 huntington disease clinical features and diagnosis
2. アルツハイマー病の疫学、病理、および病因 epidemiology pathology and pathogenesis of alzheimer disease
3. 異染性白質ジストロフィー metachromatic leukodystrophy
4. クラッベ病 krabbe disease
5. アルツハイマー病の遺伝学 genetics of alzheimer disease

Attitudes to Alzheimer's disease testing of Australian general practice patients: a cross-sectional questionnaire-based study.

Magin P1,2, Juratowitch L1, Dunbabin J1, McElduff P1, Goode S1, Tapley A2, Pond D1.
International journal of geriatric psychiatry.Int J Geriatr Psychiatry.2016 Apr;31(4):361-6. doi: 10.1002/gps.4335. Epub 2015 Aug 10.
OBJECTIVE: In view of proposed screening for presymptomatic Alzheimer's disease (AD) with advanced imaging, and blood and cerebral spinal fluid analysis, we aimed to establish levels, and associations, of acceptance of AD testing modalities by general practice patients.METHODS: A cross-sectional que
PMID 26258761

Illness representations, knowledge and motivation to perform presymptomatic testing for late-onset genetic diseases.

Leite Â1,2, Dinis MA3, Sequeiros J2,4,5, Paúl C4.
Psychology, health & medicine.Psychol Health Med.2016 Mar 7:1-6. [Epub ahead of print]
This study addresses the relation between illness representations, knowledge and motivation to perform the presymptomatic testing (PST) of subjects at-risk for Familial Amyloydotic Polyneuropathy (FAP), Huntington's disease (HD) and Machado-Joseph disease (MJD), compared with subjects at-risk for He
PMID 26947204

Presymptomatic activation of the PDGF-CC pathway accelerates onset of ALS neurodegeneration.

Lewandowski SA1, Nilsson I2, Fredriksson L3,4, Lönnerberg P3, Muhl L2, Zeitelhofer M2, Adzemovic MZ2, Nichterwitz S5, Lawrence DA4, Hedlund E5, Eriksson U6.
Acta neuropathologica.Acta Neuropathol.2016 Mar;131(3):453-64. doi: 10.1007/s00401-015-1520-2. Epub 2015 Dec 19.
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with unknown origins. Neurodegeneration in ALS mouse models occurs together with signs of disrupted blood-spinal cord barrier (BSCB) and regressed capillary network, but the molecular pathways contributing to these vascular pat
PMID 26687981

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