前体節中胚葉
WordNet
- the middle germ layer that develops into muscle and bone and cartilage and blood and connective tissue (同)mesoblast
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English Journal
- Context-Dependent Functional Divergence of the Notch Ligands DLL1 and DLL4 In Vivo.
- Preuße K1, Tveriakhina L1, Schuster-Gossler K1, Gaspar C2, Rosa AI2, Henrique D2, Gossler A1, Stauber M1.
- PLoS genetics.PLoS Genet.2015 Jun 26;11(6):e1005328. doi: 10.1371/journal.pgen.1005328. eCollection 2015.
- Notch signalling is a fundamental pathway that shapes the developing embryo and sustains adult tissues by direct communication between ligand and receptor molecules on adjacent cells. Among the ligands are two Delta paralogues, DLL1 and DLL4, that are conserved in mammals and share a similar structu
- PMID 26114479
- Dynamics of the slowing segmentation clock reveal alternating two-segment periodicity.
- Shih NP1, François P2, Delaune EA3, Amacher SL4.
- Development (Cambridge, England).Development.2015 May 15;142(10):1785-93. doi: 10.1242/dev.119057.
- The formation of reiterated somites along the vertebrate body axis is controlled by the segmentation clock, a molecular oscillator expressed within presomitic mesoderm (PSM) cells. Although PSM cells oscillate autonomously, they coordinate with neighboring cells to generate a sweeping wave of cyclic
- PMID 25968314
- MBTPS1/SKI-1/S1P proprotein convertase is required for ECM signaling and axial elongation during somitogenesis and vertebral development†.
- Achilleos A1, Huffman NT2, Marcinkiewicyz E3, Seidah NG3, Chen Q2, Dallas SL2, Trainor PA4, Gorski JP5.
- Human molecular genetics.Hum Mol Genet.2015 May 15;24(10):2884-98. doi: 10.1093/hmg/ddv050. Epub 2015 Feb 4.
- Caudal regression syndrome (sacral agenesis), which impairs development of the caudal region of the body, occurs with a frequency of about 2 live births per 100 000 newborns although this incidence rises to 1 in 350 infants born to mothers with gestational diabetes. The lower back and limbs can be a
- PMID 25652402
Japanese Journal
- Intronic delay is essential for oscillatory expression in the segmentation clock.
- Takashima Yoshiki,Ohtsuka Toshiyuki,González Aitor,Miyachi Hitoshi,Kageyama Ryoichiro
- Proceedings of the National Academy of Sciences of the United States of America 108(8), 3300-3305, 2011-02-22
- … The basic helix-loop-helix repressor gene Hes7 is cyclically expressed in the presomitic mesoderm (PSM) and regulates the somite segmentation. …
- NAID 120002970830
- 2P309 前体節中胚葉の2次元モデルによる分節時計の振動メカニズムの研究(数理生物学,第48回日本生物物理学会年会)
- Sonoda Yoshihiro,Itoh Kazuhito,Terada Tomoki P,Sasai Masaki
- 生物物理 50(SUPPLEMENT_2), S137, 2010-08-15
- NAID 110008102893
- 脊椎動物の発生過程における分節時計の分子システム(生命現象,一般)
- 伊坂 弥花子,山尾 将隆,作村 諭一 [他],金 雄,松井 貴輝,別所 康全,石井 信
- 電子情報通信学会技術研究報告. NLP, 非線形問題 108(477), 71-76, 2009-03-03
- 体節は、脊椎動物の身体が構築される過程で形成され、背骨や骨格筋、肋骨のように分節構造をもつ器官の基礎となる。発生初期では、身体の前後軸に沿って未分節中胚葉(PSM)と呼ばれる一続きの組織が存在するが、時間が経過するにつれ、前側から逐次的に分節化していくことにより体節が形成される。分節化のタイミングが周期性を示すことから、細胞内には時を刻む機構(分節時計)が存在すると考えられている。マウスの場合、H …
- NAID 110007324853
Related Links
- Watch the introductory video to learn more about our database of embryonic development for stem cell research and regenerative medicine × ... The presomitic mesoderm (PSM) is a mesoderm-derived mesenchymal tissue located ...
- Hoxa10 activity in the presomitic versus somitic mesoderm To test this idea, we used a transgenic approach in which Hoxa10 was expressed under the control of the Dll1 promoter (Beckers et al. 2000). This promoter has been shown ...
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