prepregnancy

妊娠前

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1. 妊婦の肥満：合併症と母胎管理 obesity in pregnancy complications and maternal management
2. 妊娠中の栄養 nutrition in pregnancy
3. 妊娠前の外来診察 the preconception office visit
4. Prenatal care: Patient education, health promotion, and safety of commonly used drugs
5. Familial hypercholesterolemia in adults: Treatment

English Journal

History of Infertility and Risk of Gestational Diabetes Mellitus: A Prospective Analysis of 40,773 Pregnancies.

Tobias DK, Chavarro JE, Williams MA, Buck Louis GM, Hu FB, Rich-Edwards J, Missmer SA, Zhang C.AbstractStudies of delayed conception and risk of gestational diabetes (GDM) are sparse, although common underlying mechanisms are plausible, including insulin resistance and inflammation. The association between a history of infertility and GDM was assessed prospectively among 40,773 eligible pregnancies in the US Nurses' Health Study II cohort (1989-2001). Biennial questionnaires provided updated information on infertility and several lifestyle and health-related characteristics. Multivariable log-binomial models with generalized estimating equations were used to compute risk ratios and 95% confidence intervals, adjusting for age, prepregnancy body mass index (weight (kg)/height (m)2), and additional potential confounders. GDM occurred among 1,405 (5.2%) women. A prepregnancy history of infertility was reported by 5,497 (20.5%) participants and was significantly associated with a 39% greater risk of GDM (risk ratio (RR) = 1.39, 95% confidence interval (CI): 1.24, 1.57; P < 0.001). Underlying reasons for infertility associated with GDM included ovulation disorders (RR = 1.52, 95% CI: 1.23, 1.87; P < 0.001) and tubal blockage (RR = 1.83, 95% CI: 1.20, 2.77; P = 0.005). The association of cervical mucus disorder with GDM was of borderline significance (RR = 1.70, 95% CI: 0.88, 3.30; P = 0.11). Endometriosis (RR = 1.27, 95% CI: 0.70, 2.31; P = 0.43) and male factor infertility (RR = 1.12, 95% CI: 0.78, 1.61; P = 0.55) were not associated with GDM risk. These novel findings suggest that infertility, particularly from ovulation disorders and tubal blockage, is associated with an increased GDM risk. Further research is needed to identify mechanisms or common underlying metabolic dysfunction explaining these observations.
American journal of epidemiology.Am J Epidemiol.2013 Oct 15;178(8):1219-1225. Epub 2013 Aug 15.
Studies of delayed conception and risk of gestational diabetes (GDM) are sparse, although common underlying mechanisms are plausible, including insulin resistance and inflammation. The association between a history of infertility and GDM was assessed prospectively among 40,773 eligible pregnancies i
PMID 23956097

Interpregnancy Weight Change and Risk for Adverse Perinatal Outcome.

Bogaerts A, Van den Bergh BR, Ameye L, Witters I, Martens E, Timmerman D, Devlieger R.SourceKHLim, Limburg Catholic University College, PHL University College, Department of Healthcare Research, Hasselt, the Departments of Psychology and Development and Regeneration, KU Leuven, the Center of Human Genetics, University Hospitals Leuven, and the Department of Obstetrics & Gynaecology-Division of Mother & Child, University Hospitals, Leuven, and the Department of Welfare, Public Health and Family, Flemish Government, and the Flemish Study Center for Perinatal Epidemiology, Brussels, Belgium; and the Department of Psychology, Tilburg University, Tilburg, The Netherlands.
Obstetrics and gynecology.Obstet Gynecol.2013 Oct 7. [Epub ahead of print]
OBJECTIVE:: To examine the association between interpregnancy weight change and the risk for adverse maternal and neonatal outcomes.METHODS:: All live-born singleton births delivered at 21-42 weeks of gestation in women who had their first two consecutive births between 2009 and 2011 in Flanders (th
PMID 24104777

Risk factors for urinary incontinence 1 year after the first vaginal delivery in a cohort of primiparous Danish women.

Svare JA, Hansen BB, Lose G.SourceDepartment of Obstetrics and Gynaecology, Copenhagen University Hospital Herlev, Herlev Ringvej 75, 2730, Herlev, Denmark, jens.svare@dadlnet.dk.
International urogynecology journal.Int Urogynecol J.2013 Oct 2. [Epub ahead of print]
INTRODUCTION AND HYPOTHESIS: The objective was to examine the relationship between maternal and perinatal factors and the occurrence of stress (SUI) or mixed (MUI) urinary incontinence (UI) 1 year after the first vaginal delivery in primiparous women.METHODS: Participants in this prospective cohort
PMID 24085146