English Journal

Acute and chronic effects of selective serotonin reuptake inhibitor treatment on fear conditioning: Implications for underlying fear circuits.

Burghardt NS, Bauer EP.SourceColumbia University, Departments of Neuroscience and Psychiatry, 1051 Riverside Drive, Unit 87, New York, NY 10032, United States; The New York State Psychiatric Institute, Division of Integrative Neuroscience, New York, NY 10032, United States. Electronic address: nsb2113@columbia.edu.
Neuroscience.Neuroscience.2013 Sep 5;247:253-72. doi: 10.1016/j.neuroscience.2013.05.050. Epub 2013 Jun 1.
Selective serotonin reuptake inhibitors (SSRIs) are widely used for the treatment of a spectrum of anxiety disorders, yet paradoxically they may increase symptoms of anxiety when treatment is first initiated. Despite extensive research over the past 30years focused on SSRI treatment, the precise mec
PMID 23732229

Involvement of prelimbic medial prefrontal cortex in panic-like elaborated defensive behaviour and innate fear-induced antinociception elicited by GABAA receptor blockade in the dorsomedial and ventromedial hypothalamic nuclei: role of the endocannabinoid CB1 receptor.

de Freitas RL, Salgado-Rohner CJ, Hallak JE, de Souza Crippa JA, Coimbra NC.SourceLaboratory of Neuroanatomy and Neuropsychobiology, Department of Pharmacology, Ribeirão Preto Medical School of the University of São Paulo, Brazil.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP).Int J Neuropsychopharmacol.2013 Sep;16(8):1781-98. doi: 10.1017/S1461145713000163. Epub 2013 Mar 25.
It has been shown that GABAA receptor blockade in the dorsomedial and ventromedial hypothalamic nuclei (DMH and VMH, respectively) induces elaborated defensive behavioural responses accompanied by antinociception, which has been utilized as an experimental model of panic attack. Furthermore, the pre
PMID 23521775

Segregation of parallel inputs to the anteromedial and anteroventral thalamic nuclei of the rat.

Wright NF, Vann SD, Erichsen JT, O'Mara SM, Aggleton JP.SourceSchool of Psychology, Cardiff University, Cardiff, United Kingdom.
The Journal of comparative neurology.J Comp Neurol.2013 Sep 1;521(13):2966-86. doi: 10.1002/cne.23325.
Many brain structures project to both the anteroventral thalamic nucleus and the anteromedial thalamic nucleus. In the present study, pairs of different tracers were placed into these two thalamic sites in the same rats to determine the extent to which these nuclei receive segregated inputs. Only in
PMID 23504917

Japanese Journal

Synaptic relationships between axon terminals from the mediodorsal thalamic nucleus and gamma-aminobutyric acidergic cortical cells in the prelimbic cortex of the rat