pregnanediol

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WordNet

1. a compound found in womens urine during certain phases of the menstrual cycle and in the urine of pregnant women

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/04/13 13:23:09」(JST)

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Pregnanediol is an inactive product that forms when the body breaks down the hormone progesterone. A test can be done to measure the amount of pregnanediol in urine. The urine test offers an indirect way to measure progesterone levels in the body.

Pregnanediol
IUPAC name (3R,5R,8R,9S,10S,13S,14S,17S)-17-[(1S)-1-hydroxyethyl]-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol
Other names 5β-Pregnane-3α,20α-diol
Identifiers
CAS number	80-92-2 Y
PubChem	219833
ChemSpider	190585 Y
UNII	JR3JD1Y22C Y
ChEMBL	CHEMBL269897 Y
Jmol-3D images	Image 1
SMILES O[C@@H]4CC[C@]3([C@H](CC[C@H]2[C@@H]1CC[C@@H]([C@@]1(C)CC[C@@H]23)[C@@H](O)C)C4)C
InChI InChI=1S/C21H36O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h13-19,22-23H,4-12H2,1-3H3/t13-,14+,15+,16-,17+,18-,19-,20-,21+/m0/s1 Y Key: YWYQTGBBEZQBGO-BERLURQNSA-N Y InChI=1/C21H36O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h13-19,22-23H,4-12H2,1-3H3/t13-,14+,15+,16-,17+,18-,19-,20-,21+/m0/s1 Key: YWYQTGBBEZQBGO-BERLURQNBW
Properties
Molecular formula	C21H36O2
Molar mass	320.51 g mol−1
Y (verify) (what is: Y/N?) Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Pregnanediol is a steroid.

References

UpToDate Contents

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• 1. 出産後および流産後の避妊 postpartum and postabortion contraception
• 2. 先天性副腎過形成の稀な原因 uncommon causes of congenital adrenal hyperplasia
• 3. 産後ケアの概要 overview of postpartum care

English Journal

• The role of progestogens in regulating matrix metalloproteinase activity in macrophages and microglial cells.

• Hwang-Levine J, Stanczyk FZ, Hodis HN.SourceDepartment of Pharmacology and Pharmaceutical Sciences, School of Pharmacy, University of Southern California, 1985 Zonal Ave., PSC 612, Los Angeles, CA, 90033, USA, julianah@usc.edu.
• Neurochemical research.Neurochem Res.2011 Oct;36(10):1870-5. Epub 2011 May 27.
• Although the systemic effects of progestogens have been extensively studied, little is known in regards to the cellular effects of these compounds. Using a cellular model for vascular (macrophages) and brain (microglial) cells, we studied the effects of various progestogens, either alone or in combi
• PMID 21617962

• The effects of a long-term psychosocial stress on reproductive indicators in the baboon.

• O'Connor KA, Brindle E, Shofer J, Trumble BC, Aranda JD, Rice K, Tatar M.SourceDepartment of Anthropology, University of Washington, Seattle, WA 98195, USA. oconnork@u.washington.edu
• American journal of physical anthropology.Am J Phys Anthropol.2011 Aug;145(4):629-38. doi: 10.1002/ajpa.21538. Epub 2011 Jun 23.
• Psychosocial stress is thought to negatively impact fecundity, but human studies are confounded by variation in nutrition and lifestyle. Baboons offer a useful model to test the effect of prolonged mild stress on reproductive indicators in a controlled setting. Following relocation from social group
• PMID 21702002

Japanese Journal

• プレグナンジオール(P2),プレグナントリオール(P3) (広範囲 血液・尿化学検査 免疫学的検査(第7版・4)その数値をどう読むか) -- (内分泌学的検査 性線・胎盤関係)

• 藤間 芳郎,矢内原 巧
• 日本臨床 68(-) (982), 466-470, 2010-07
• NAID 40017200786

• ジャイアントパンダ(Ailuropoda melanoleuca)における人工授精と死産

• 浜 夏樹,黄 炎,兼光 秀泰,大山 裕二郎,馬 強,羅 波,李 果,太田 宜伯,楠 比呂志,川上 博司,ACOSTA Tomas J.,奥田 潔,王 鵬彦,石川 理
• Japanese journal of zoo and wildlife medicine 14(2), 119-123, 2009-09
• 神戸市立王子動物園のジャイアントパンダにおいて2007年の発情時に新鮮および冷蔵保存した精液を用いて3日間連続で人工授精(AI)を行った。AIの適期は尿中エストロングルクロニド濃度の測定から推測した。人工授精後は尿中プレグナンジオールグルクロニド(PdG)濃度の変化を監視した。PdG濃度は妊娠後期に過去6年間と比べると異常な変動を示した。結果的に最終AI後137日目に破水し,さらにその9日後に死産 …
• NAID 110007465857

Related Links

• Pregnanediol - Wikipedia, the free encyclopedia

Pregnanediol is an inactive product that forms when the body breaks down the hormone progesterone. A test can be done to measure the amount of pregnanediol in urine. The urine test offers an indirect way to measure progesterone levels in ...

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