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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2012/08/18 19:50:21」(JST)

Prednimustine is a drug used in chemotherapy. It is the ester formed from two other drugs, prednisolone and chlorambucil.

It can be associated with myoclonus.^[1]

References

^ Monnerat C, Gander M, Leyvraz S (January 1997). "A rare case of prednimustine-induced myoclonus". J. Natl. Cancer Inst. 89 (2): 173–4. doi:10.1093/jnci/89.2.173. PMID 8998190. http://jnci.oxfordjournals.org/cgi/pmidlookup?view=long&pmid=8998190.

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Impact of first- and second-line treatment for Hodgkin's lymphoma on the incidence of AML/MDS and NHL--experience of the German Hodgkin's Lymphoma Study Group analyzed by a parametric model of carcinogenesis.

Scholz M1, Engert A, Franklin J, Josting A, Diehl V, Hasenclever D, Loeffler M; German Hodgkin's Lymphoma Study Group.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO.Ann Oncol.2011 Mar;22(3):681-8. doi: 10.1093/annonc/mdq408. Epub 2010 Aug 18.
BACKGROUND: Using a parametric carcinogenesis model, we disentangle the superimposing effects of primary and relapse therapies of Hodgkin's disease on secondary neoplasias.PATIENTS AND METHODS: We analyze eight randomized trials of the German Hodgkin's lymphoma study group [5357 individuals, 67 seco
PMID 20720088

Yamaguchi M.
[Rinshō ketsueki] The Japanese journal of clinical hematology.Rinsho Ketsueki.2008 Aug;49(8):553-8.
PMID 18800601

Epstein-Barr virus infected natural killer cell lymphoma in a patient with hypersensitivity to mosquito bite.

Cho JH1, Kim HS, Ko YH, Park CS.
The Journal of infection.J Infect.2006 Jun;52(6):e173-6. Epub 2005 Oct 24.
Hypersensitivity to mosquito bite (HMB) can occur in association with chronic Epstein-Barr virus (EBV) infection and natural killer (NK) cell leukaemia/lymphoma, which was named 'Tokura-Ishihara disease'. This disease is very rare and most previous reports have been documented in Japan. We present a
PMID 16246422

Combination of oral idarubicin and prednimustine in advanced breast cancer: a phase II study.

リンク元	「プレドニムスチン」

Prednimustine
Systematic (IUPAC) name
	(11β)-11,17-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl 4-{4-[bis(2-chloroethyl)amino]phenyl}butanoate
Clinical data
Pregnancy cat.	?
Legal status	?
Identifiers
CAS number	29069-24-7
ATC code	L01AA08
PubChem	CID 34457
UNII	9403SIO2S8
KEGG	C19512
Synonyms	[2-[(8S,9S,10R,11S,13S,14S,17R)-11,17-Dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] 4-[4-[bis(2-chloroethyl)amino]phenyl]butanoate
Chemical data
Formula	C35H45Cl2NO6
Mol. mass	646.64 g/mol
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