WordNet

in a powerful manner; "the federal government replaced the powerfully pro-settler Sir Godfrey Huggins with the even tougher and more determined ex-trade unionist" (同)strongly
imposing in scale or scope or degree or power; "massive retaliatory power"; "a massive increase in oil prices"; "massive changes"
imposing in size or bulk or solidity; "massive oak doors"; "Moores massive sculptures"; "the monolithic proportions of Stalinist architecture"; "a monumental scale" (同)monolithic, monumental
being the same substance throughout; "massive silver"
consisting of great mass; containing a great quantity of matter; "Earth is the most massive of the terrestrial planets"
(of a male) capable of copulation (同)virile
having great influence (同)powerful
having or wielding force or authority; "providing the ground soldier with increasingly potent weapons" (同)strong
having a strong physiological or chemical effect; "a potent toxin"; "potent liquor"; "a potent cup of tea", "a stiff drink" (同)strong, stiff
tending to give force or emphasis; "an intensive adverb"
characterized by a high degree or intensity; often used as a combining form; "the questioning was intensive"; "intensive care"; "research-intensive"; "a labor-intensive industry"
of agriculture; intended to increase productivity of a fixed area by expending more capital and labor; "intensive agriculture"; "intensive conditions"
with a possibility of becoming actual; "he is potentially dangerous"; "potentially useful"
in an intensive manner; "he studied the snake intensively"
having great power or force or potency or effect; "the most powerful government in western Europe"; "his powerful arms"; "a powerful bomb"; "the horses powerful kick"; "powerful drugs"; "a powerful argument"

PrepTutorEJDIC

力強く,強力に,強烈に
『大きくて重い』,どっしりした;大規模な / (容ぼう,特に頭が)がっちりした / (精神などが)しっかりした,堂々とした / (投薬量が)定量以上の
《文》(特に政治的に)有力な,強力な / (薬・酒などが)効きめのある / (議論などが)説得力のある,力強い / (男性が)性交可能な
『集中的な』,徹底的な,強度の,激しい / (語が)強意の,強調の / =intensifier
可能性を秘めて,潜在的に
強く,激しく;集中的に
『強力な』,強い / 効果的な,ききめの強い / 勢力のある,有力な

UpToDate Contents

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1. ドラッグを注射している患者における肺疾患の概要 overview of pulmonary disease in injection drug users
2. パーソナリティ障害患者との治療関係へのアプローチ approaches to the therapeutic relationship in patients with personality disorders
3. 妊婦の薬物乱用 substance misuse in pregnant women
4. 特発性肺線維症の予後とモニタリング prognosis and monitoring of idiopathic pulmonary fibrosis
5. 2型糖尿病の予防 prevention of type 2 diabetes mellitus

English Journal

DAMGO in the central amygdala alleviates the affective dimension of pain in a rat model of inflammatory hyperalgesia.

Zhang RX, Zhang M, Li A, Pan L, Berman BM, Ren K, Lao L.SourceCenter for Integrative Medicine, School of Medicine, University of Maryland, Baltimore, MD 21201, USA. Electronic address: Rzhan001@umaryland.edu.
Neuroscience.Neuroscience.2013 Nov 12;252:359-66. doi: 10.1016/j.neuroscience.2013.08.030. Epub 2013 Aug 28.
Pain has sensory-discriminative and emotional-affective dimensions. Recent studies show that the affective component can be assessed with a conditioned place avoidance (CPA) test. We hypothesized that systemic morphine before a post-conditioning test would more potently attenuate the affective aspec
PMID 23994597

Evaluating Effectively Maintained Inequality: School and post-school transitions, socioeconomic background, academic ability and curricular placement.

Marks GN.SourceMelbourne Institute of Applied Economic and Social Research, Faculty of Business and Economics Building, The University of Melbourne, 111 Barry Street, Victoria 3010, Australia. Electronic address: gmarks@unimelb.edu.au.
Social science research.Soc Sci Res.2013 Nov;42(6):1635-49. doi: 10.1016/j.ssresearch.2013.07.004. Epub 2013 Jul 16.
Effectively Maintained Inequality (EMI) is proposed as an explanation for contemporary socioeconomic inequalities in education. Socioeconomic inequalities are 'maintained' by students from lower socioeconomic backgrounds taking less advantageous curricula influencing their post-school destinations.
PMID 24090857

Nucleus accumbens responses differentiate execution and restraint in reward-directed behavior.

Roitman JD, Loriaux AL.SourceUniv. Illinois Chicago.
Journal of neurophysiology.J Neurophysiol.2013 Oct 30. [Epub ahead of print]
Our behavior is powerfully driven by environmental cues that signal the availability of rewarding stimuli. We frequently encounter stimuli - a bowl of candy or smartphone alert - that trigger actions to obtain those rewards, even though there may positive outcomes associated with not acting. The ina
PMID 24174652

Comparative Studies of the Binding of Six Phthalate Plasticizers to Pepsin by Multi-spectroscopic Approach and Molecular Modeling.

Wang Y, Zhang H.AbstractTo explore the binding mechanism of phthalate plasticizers with digestive proteases, their effects on conformation and activity of pepsin by multi-spectroscopic approach and molecular modeling were investigated. Fluorescence spectra combined with UV-vis and circular dichroism (CD) spectra measurements indicated that the six phthalate plasticizers induced the changes of tertiary and secondary structure of pepsin. The solvent polarity of environment around both Trp and Tyr residues on pepsin were affected by phthalate plasticizers. By analyzing the fluorescence quenching and theoretical calculation data, it was concluded that a binding site exists for each phthalate plasticizer in pepsin with different binding ability. The hydrophobic, hydrogen bonding and π-π sticking interactions were involved in the interactions between pepsin and phthalate plasticizers. Moreover, the activity assay indicated that phthalate plasticizers were not powerfully inhibitors or activators for pepsin. These studies demonstrated that phthalate plasticizers could cause some negative effects on pepsin. The present studies may provide a way to analyze the biological safety of phthalate plasticizers on digestive proteases or other proteins.
Journal of agricultural and food chemistry.J Agric Food Chem.2013 Oct 28. [Epub ahead of print]
To explore the binding mechanism of phthalate plasticizers with digestive proteases, their effects on conformation and activity of pepsin by multi-spectroscopic approach and molecular modeling were investigated. Fluorescence spectra combined with UV-vis and circular dichroism (CD) spectra measuremen
PMID 24164277