porokeratosis

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/05/21 00:27:50」(JST)

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Porokeratosis
Classification and external resources
A porokeratosis lesion in a patient with disseminated superficial actinic porokeratosis.
DiseasesDB	31356
eMedicine	article/1059123
MeSH	D017499

Porokeratosis is a specific disorder of keratinization that is characterized histologically by the presence of a cornoid lamella, a thin column of closely stacked, parakeratotic cells extending through the stratum corneum with a thin or absent granular layer.

Types

Porokeratosis may be divided into the following clinical types:

• Classic porokeratosis Mibelli
• Disseminated superficial actinic porokeratosis
• Disseminated superficial porokeratosis
• Porokeratosis palmaris et plantaris disseminata
• Linear porokeratosis
• Punctate porokeratosis

However, additional types have also been described:

• Porokeratosis plantaris discreta

Pathology

Micrograph of a case of porokeratosis showing a characteristic cornoid lamella (dark pink/red structure in the right/upper portion of the image). H&E stain.

Porokeratosis has a characteristic histomorphologic feature known as a cornoid lamella.

See also

• List of cutaneous conditions
• List of cutaneous conditions associated with increased risk of nonmelanoma skin cancer

References

UpToDate Contents

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• 1. 汗孔角化症 porokeratosis
• 2. 線状苔癬 lichen striatus
• 3. 環状皮膚病変が認められる患者に対するアプローチ approach to the patient with annular skin lesions
• 4. 肝移植後の皮膚障害の概要 overview of dermatologic problems following liver transplantation
• 5. 疣贅状表皮発育異常症 epidermodysplasia verruciformis

English Journal

• Altered gene expression in squamous cell carcinoma arising from congenital unilateral linear porokeratosis.

• Scola N, Skrygan M, Wieland U, Kreuter A, Gambichler T.SourceDepartment of Dermatology, Venereology and Allergology, Ruhr-University Bochum, Germany Institute of Virology, National Reference Centre for Papilloma- and Polyomaviruses, University of Cologne, Cologne, Germany.
• Clinical and experimental dermatology.Clin Exp Dermatol.2012 Oct;37(7):781-5. doi: 10.1111/j.1365-2230.2012.04393.x.
• Congenital unilateral linear porokeratosis (CULP) is a rare disorder of keratinization that shares clinical and molecular similarities with psoriasis. It also has an increased risk for malignant transformation to cutaneous squamous cell carcinoma (SCC). We investigated the expression of psoriasin, h
• PMID 22998543

Japanese Journal

• 治療 日光表在播種型汗孔角化症の1例 : イミキモドクリームによる治療の試み

• 勝野 正子,宇津宮 まりか,竹下 芳裕 [他]
• 皮膚科の臨床 56(8), 1155-1158, 2014-08
• NAID 40020180601

• 基底細胞癌を発生した表在播種型汗孔角化症の1例 (特集 角化症・炎症性角化症)

• 中村 保夫,水野 みどり,森 如
• 皮膚科の臨床 56(8), 1106-1109, 2014-08
• NAID 40020180329

• 5%イミキモドクリーム外用が奏効したと考えられた汗孔角化症の1例 (特集 角化症・炎症性角化症)

• 金子 綾,上野 孝,船坂 陽子 [他]
• 皮膚科の臨床 56(8), 1102-1105, 2014-08
• NAID 40020180319

Related Links

• Porokeratosis - Medscape Reference

26 Oct 2012 ... Porokeratosis. Porokeratosis is a clonal disorder of keratinization characterized by one or more atrophic patches surrounded by a clinically and histologically distinctive hyperkeratotic ridgelike border called the cornoid ...

• Porokeratosis - Wikipedia, the free encyclopedia

Porokeratosis is a specific disorder of keratinization that is characterized histologically by the presence of a cornoid lamella, a thin column of closely stacked, parakeratotic cells extending through the stratum corneum with a thin or absent ...

Related Pictures